Drug General Information
Drug ID
D0G2LT
Former ID
DPR000095
Drug Name
RGH-1756
Drug Type
Small molecular drug
Indication Schizophrenia [ICD9: 295; ICD10:F20] Terminated [536463]
Company
Gedeon Richter
Structure
Download
2D MOL

3D MOL

Formula
C15H18N3O3+
Canonical SMILES
COC1=CC=C(C=C1)C2=N[N+](=C(C=C2)N)CCCC(=O)O
InChI
1S/C15H17N3O3/c1-21-12-6-4-11(5-7-12)13-8-9-14(16)18(17-13)10-2-3-15(19)20/h4-9,16H,2-3,10H2,1H3,(H,19,20)/p+1
InChIKey
ACVGNKYJVGNLIL-UHFFFAOYSA-O
CAS Number
CAS 207277-37-0
PubChem Compound ID
PubChem Substance ID
Target and Pathway
Target(s) D(3) dopamine receptor Target Info Antagonist [536463]
KEGG Pathway Neuroactive ligand-receptor interaction
Dopaminergic synapse
Reactome Dopamine receptors
G alpha (i) signalling events
WikiPathways Monoamine GPCRs
GPCRs, Class A Rhodopsin-like
GPCR ligand binding
GPCR downstream signaling
Nicotine Activity on Dopaminergic Neurons
GPCRs, Other
References
Ref 536463The pipeline and future of drug development in schizophrenia. Mol Psychiatry. 2007 Oct;12(10):904-22. Epub 2007 Jul 31.
Ref 536463The pipeline and future of drug development in schizophrenia. Mol Psychiatry. 2007 Oct;12(10):904-22. Epub 2007 Jul 31.

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