Drug Information
| Drug General Information | |||||
|---|---|---|---|---|---|
| Drug ID |
D0B9AO
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| Former ID |
DAP001257
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| Drug Name |
Saprisartan
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| Synonyms |
Saprisartan potassium; GR 138950; GR-138950; GR-138950C; GR-138950X; 3-[[3-bromo-2-[2-(trifluoromethylsulfonylamino)phenyl]-1-benzofuran-5-yl]methyl]-5-cyclopropyl-2-ethylimidazole-4-carboxamide
|
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| Drug Type |
Small molecular drug
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| Therapeutic Class |
Antihypertensive Agents
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| Structure |
|
Download2D MOL |
|||
| Formula |
C25H22BrF3N4O4S
|
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| InChI |
InChI=1S/C25H22BrF3N4O4S/c1-2-19-31-21(14-8-9-14)22(24(30)34)33(19)12-13-7-10-18-16(11-13)20(26)23(37-18)15-5-3-4-6-17(15)32-38(35,36)25(27,28)29/h3-7,10-11,14,32H,2,8-9,12H2,1H3,(H2,30,34)
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| InChIKey |
DUEWVPTZCSAMNB-UHFFFAOYSA-N
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| CAS Number |
CAS 146623-69-0
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| PubChem Compound ID | |||||
| PubChem Substance ID | |||||
| Target and Pathway | |||||
| Target(s) | Type-1 angiotensin II receptor | Target Info | Antagonist | [534931] | |
| NetPath Pathway | TGF_beta_Receptor Signaling Pathway | ||||
| Pathway Interaction Database | Arf6 trafficking events | ||||
| Arf6 signaling events | |||||
| Angiopoietin receptor Tie2-mediated signaling | |||||
| PathWhiz Pathway | Angiotensin Metabolism | ||||
| Muscle/Heart Contraction | |||||
| References | |||||
| Ref 534931 | Pharmacological properties of angiotensin II receptor antagonists. Can J Cardiol. 1999 Nov;15 Suppl F:26F-8F. | ||||
| Ref 541954 | (http://www.guidetopharmacology.org/) Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 6899). | ||||
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