Drug Information
| Drug General Information | |||||
|---|---|---|---|---|---|
| Drug ID |
D09XGK
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| Former ID |
DIB004775
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| Drug Name |
Testetrol
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| Synonyms |
Testetrol (oral, hypogonadism); T2 (oral, hypogonadism), Pantarhei; Testetrol (oral, hypogonadism), Pantarhei; Testosterone agonist (oral, hypogonadism), Pantarhei
|
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| Indication | Hypogonadism [ICD9: 257.2; ICD10:E23.0, E28.3, E29.1] | Investigative | [1] | ||
| Company |
Pantarhei Bioscience BV
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| Structure |
|
Download2D MOL |
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| Canonical SMILES |
[C@@]12(C(=CC(=O)CC2)CC[C@@H]2[C@@H]1CC[C@]1([C@H]2C(C[<br />C@@H]1O)O)C)C
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| Target and Pathway | |||||
| Target(s) | Androgen receptor | Target Info | Agonist | [1] | |
| KEGG Pathway | Oocyte meiosis | ||||
| Pathways in cancer | |||||
| Prostate cancer | |||||
| NetPath Pathway | EGFR1 Signaling Pathway | ||||
| AndrogenReceptor Signaling Pathway | |||||
| FSH Signaling Pathway | |||||
| Pathway Interaction Database | Regulation of nuclear SMAD2/3 signaling | ||||
| Coregulation of Androgen receptor activity | |||||
| Regulation of Androgen receptor activity | |||||
| Nongenotropic Androgen signaling | |||||
| Regulation of nuclear beta catenin signaling and target gene transcription | |||||
| FOXA1 transcription factor network | |||||
| Notch-mediated HES/HEY network | |||||
| Reactome | Nuclear Receptor transcription pathway | ||||
| Activated PKN1 stimulates transcription of AR (androgen receptor) regulated genes KLK2 and KLK3 | |||||
| WikiPathways | SIDS Susceptibility Pathways | ||||
| Integrated Pancreatic Cancer Pathway | |||||
| Prostate Cancer | |||||
| Integrated Breast Cancer Pathway | |||||
| Nuclear Receptors | |||||
| Androgen receptor signaling pathway | |||||
| References | |||||
| REF 1 | Estetrol review: profile and potential clinical applications. Climacteric. 2008;11 Suppl 1:47-58. | ||||
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