Drug Information
Drug General Information | |||||
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Drug ID |
D09BHB
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Former ID |
DAP000777
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Drug Name |
Tolmetin
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Synonyms |
Tolectin; Tolmetina; Tolmetine; Tolmetino; Tolmetinum; Tolmetina [DCIT]; MCN 2559; McN-2559; Tolectin (TN); Tolmetin Sodium, Dihydrate; Tolmetine [INN-French]; Tolmetino [INN-Spanish]; Tolmetinum [INN-Latin]; Tolmetin (USAN/INN); Tolmetin [USAN:BAN:INN]; Acido 1-metil-5-(p-tolnil)-pirrol-2-acetico; Acido 1-metil-5-(p-tolnil)-pirrol-2-acetico [Spanish]; 1-Methyl-5-(4-methylbenzoyl)-1H-pyrrole-2-acetic acid; 1-Methyl-5-(4-methylbenzoyl)-pyrrole-2-acetic acid; 1-Methyl-5-p-toluoylpyrrole-2-acetic acid; 2-[1-methyl-5-(4-methylbenzoyl)pyrrol-2-yl]acetic acid; 5-(p-Toluoyl)-1-methylpyrrole-2-acetic acid
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Drug Type |
Small molecular drug
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Therapeutic Class |
Antiinflammatory Agents
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Company |
Ortho Mcneil Janssen Pharmaceuticals Inc
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Structure |
Download2D MOL |
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Formula |
C15H15NO3
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InChI |
InChI=1S/C15H15NO3/c1-10-3-5-11(6-4-10)15(19)13-8-7-12(16(13)2)9-14(17)18/h3-8H,9H2,1-2H3,(H,17,18)
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InChIKey |
UPSPUYADGBWSHF-UHFFFAOYSA-N
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CAS Number |
CAS 26171-23-3
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PubChem Compound ID | |||||
PubChem Substance ID |
9358, 4720233, 7849414, 7980812, 8153389, 10516103, 11335388, 11360627, 11363829, 11366391, 11368953, 11371706, 11373936, 11377115, 11461599, 11466884, 11468004, 11484726, 11486528, 11489021, 11490419, 11492174, 11494749, 14774544, 29224552, 46507060, 47365060, 47440134, 47515198, 47810629, 48034985, 48184877, 48259100, 48259101, 49836361, 50037570, 50576757, 57322816, 76715631, 85787331, 85789564, 92309062, 93166626, 103273527, 104136818, 104309430, 126408174, 126650547, 126664366, 129402959
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SuperDrug ATC ID |
M01AB03; M02AA21
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SuperDrug CAS ID |
cas=026171233
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Target and Pathway | |||||
Target(s) | Prostaglandin G/H synthase 2 | Target Info | Inhibitor | [537246] | |
KEGG Pathway | Arachidonic acid metabolism | ||||
Metabolic pathways | |||||
NF-kappa B signaling pathway | |||||
VEGF signaling pathway | |||||
TNF signaling pathway | |||||
Retrograde endocannabinoid signaling | |||||
Serotonergic synapse | |||||
Ovarian steroidogenesis | |||||
Oxytocin signaling pathway | |||||
Regulation of lipolysis in adipocytes | |||||
Leishmaniasis | |||||
Pathways in cancer | |||||
Chemical carcinogenesis | |||||
MicroRNAs in cancer | |||||
Small cell lung cancer | |||||
PathWhiz Pathway | Arachidonic Acid Metabolism | ||||
References | |||||
Ref 538251 | FDA Approved Drug Products from FDA Official Website. 2009. Application Number: (ANDA) 073290. | ||||
Ref 542334 | (http://www.guidetopharmacology.org/) Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 7311). | ||||
Ref 551871 | Drugs@FDA. U.S. Food and Drug Administration. U.S. Department of Health & Human Services. 2015 |
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