Drug General Information
Drug ID
D08AOG
Former ID
DNC005433
Drug Name
2,2-Dimethoxy-1,2-diphenyl-ethanone
Drug Type
Small molecular drug
Indication Discovery agent Investigative [527510]
Structure
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2D MOL

3D MOL

Formula
C16H16O3
Canonical SMILES
COC(C1=CC=CC=C1)(C(=O)C2=CC=CC=C2)OC
InChI
1S/C16H16O3/c1-18-16(19-2,14-11-7-4-8-12-14)15(17)13-9-5-3-6-10-13/h3-12H,1-2H3
InChIKey
KWVGIHKZDCUPEU-UHFFFAOYSA-N
PubChem Compound ID
Target and Pathway
Target(s) Liver carboxylesterase Target Info Inhibitor [527510]
KEGG Pathway Drug metabolism - other enzymes
Metabolic pathways
Pathway Interaction Database E2F transcription factor network
WikiPathways NRF2 pathway
Nuclear Receptors Meta-Pathway
Heroin metabolism
Irinotecan Pathway
Fluoropyrimidine Activity
Phase I biotransformations, non P450
References
Ref 527510J Med Chem. 2005 Apr 21;48(8):2906-15.Identification and characterization of novel benzil (diphenylethane-1,2-dione) analogues as inhibitors of mammalian carboxylesterases.
Ref 527510J Med Chem. 2005 Apr 21;48(8):2906-15.Identification and characterization of novel benzil (diphenylethane-1,2-dione) analogues as inhibitors of mammalian carboxylesterases.

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