| Drug General Information |
| Drug ID |
D07TAJ
|
| Former ID |
DNC010070
|
| Drug Name |
Ethyl 7-methoxy-2-oxo-2H-chromene-3-carboxylate
|
| Drug Type |
Small molecular drug
|
| Indication |
Discovery agent
|
Investigative |
[1]
|
|---|
| Structure |
|
Download
2D MOL
3D MOL
|
| Formula |
C13H12O5
|
| Canonical SMILES |
CCOC(=O)C1=CC2=C(C=C(C=C2)OC)OC1=O
|
| InChI |
1S/C13H12O5/c1-3-17-12(14)10-6-8-4-5-9(16-2)7-11(8)18-13(10)15/h4-7H,3H2,1-2H3
|
| InChIKey |
FWFVXBZXJKTVGL-UHFFFAOYSA-N
|
| PubChem Compound ID |
|
| Target and Pathway |
| Target(s) |
Carbonic anhydrase IV |
Target Info |
Inhibitor |
[1]
|
|---|
| Carbonic anhydrase |
Target Info |
Inhibitor |
[1]
|
| Carbonic anhydrase XII |
Target Info |
Inhibitor |
[1]
|
| Carbonic anhydrase XIV |
Target Info |
Inhibitor |
[1]
|
| Carbonic anhydrase VI |
Target Info |
Inhibitor |
[1]
|
| Carbonic anhydrase IX |
Target Info |
Inhibitor |
[1]
|
|
KEGG Pathway
|
Nitrogen metabolism
|
|
Proximal tubule bicarbonate reclamationhsa00910:Nitrogen metabolismhsa00910:Nitrogen metabolismhsa00910:Nitrogen metabolismhsa00910:Nitrogen metabolism
|
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NetPath Pathway
|
TGF_beta_Receptor Signaling Pathway
|
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Pathway Interaction Database
|
HIF-1-alpha transcription factor network
|
|
Reactome
|
Erythrocytes take up carbon dioxide and release oxygen
|
|
Erythrocytes take up oxygen and release carbon dioxide
|
|
Reversible hydration of carbon dioxideR-HSA-1475029:Reversible hydration of carbon dioxideR-HSA-1475029:Reversible hydration of carbon dioxideR-HSA-1475029:Reversible hydration of carbon dioxideR-HSA-1234158:Regulation of gene expression by Hypoxia-inducible Factor
|
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Reversible hydration of carbon dioxide
|
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WikiPathways
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Reversible Hydration of Carbon Dioxide
|
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Uptake of Carbon Dioxide and Release of Oxygen by Erythrocytes
|
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Uptake of Oxygen and Release of Carbon Dioxide by ErythrocytesWP2770:Reversible Hydration of Carbon Dioxide
|
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miR-targeted genes in muscle cell - TarBase
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miR-targeted genes in leukocytes - TarBase
|
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miR-targeted genes in epithelium - TarBaseWP2770:Reversible Hydration of Carbon DioxideWP2770:Reversible Hydration of Carbon DioxideWP2877:Vitamin D Receptor Pathway
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Regulation of Hypoxia-inducible Factor (HIF) by Oxygen
|
| References |
| REF 1 | J Med Chem. 2010 Jan 14;53(1):335-44.Deciphering the mechanism of carbonic anhydrase inhibition with coumarins and thiocoumarins. |
|---|
