Drug Information

Drug General Information
Drug ID
D07JVL
Former ID
DIB012028
Drug Name
Diazepam
Synonyms
Diazepam (intranasal, epilepsy)
Drug Type
Small molecular drug
Indication Epilepsy [ICD10:G40] Approved [524426], [540319]
Company
Archimedes Pharma Ltd
Structure
Download
2D MOL

3D MOL
Formula
C16H13ClN2O
InChI
InChI=1S/C16H13ClN2O/c1-19-14-8-7-12(17)9-13(14)16(18-10-15(19)20)11-5-3-2-4-6-11/h2-9H,10H2,1H3
InChIKey
AAOVKJBEBIDNHE-UHFFFAOYSA-N
PubChem Compound ID
3016
PubChem Substance ID
9163, 118340, 442487, 589069, 597369, 866565, 3248698, 5349992, 7847359, 7849643, 7887249, 7945393, 7979063, 8027939, 8150113, 8151919, 10522913, 11336142, 11361381, 11372878, 11374151, 11462353, 11491595, 11492391, 14799843, 24893306, 24894120, 26719642, 29222163, 46386554, 46505210, 47440353, 47515391, 47662377, 48259330, 48413548, 48415873, 48423248, 49742658, 49854346, 50122777, 50660483, 53788455, 56313613, 57321555, 57654125, 81041007, 85788516, 85856297, 92308494
Target and Pathway
Target(s) Peripheral-type benzodiazepine receptor Target Info Agonist [530408]
KEGG Pathway Neuroactive ligand-receptor interaction
HTLV-I infection
References
Ref 524426ClinicalTrials.gov (NCT01939093) Therapeutic Effect of Quetiapine on Methamphetamine-Induced Psychosis. U.S. National Institutes of Health.
Ref 540319(http://www.guidetopharmacology.org/) Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 3364).
Ref 530408Translocator protein (18 kDa) mediates the pro-growth effects of diazepam on Ehrlich tumor cells in vivo. Eur J Pharmacol. 2010 Jan 25;626(2-3):131-8.

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