Drug Information
| Drug General Information | |||||
|---|---|---|---|---|---|
| Drug ID |
D07HFU
|
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| Former ID |
DNC007677
|
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| Drug Name |
MCL-446
|
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| Drug Type |
Small molecular drug
|
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| Indication | Discovery agent | Investigative | [528787] | ||
| Structure |
|
Download2D MOL |
|||
| Formula |
C22H31N3O
|
||||
| Canonical SMILES |
CNC(=O)NC1=CC2=C(CC3C4C2(CCCC4)CCN3CC5CC5)C=C1
|
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| InChI |
1S/C22H31N3O/c1-23-21(26)24-17-8-7-16-12-20-18-4-2-3-9-22(18,19(16)13-17)10-11-25(20)14-15-5-6-15/h7-8,13,15,18,20H,2-6,9-12,14H2,1H3,(H2,23,24,26)/t18-,20+,22+/m0/s1
|
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| InChIKey |
NXVBILHYMWWGLP-CZTZKLFOSA-N
|
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| PubChem Compound ID | |||||
| Target and Pathway | |||||
| Target(s) | Mu-type opioid receptor | Target Info | Inhibitor | [528787] | |
| Delta-type opioid receptor | Target Info | Inhibitor | [528787] | ||
| Kappa-type opioid receptor | Target Info | Inhibitor | [528787] | ||
| NetPath Pathway | TCR Signaling Pathway | ||||
| PANTHER Pathway | Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway | ||||
| Heterotrimeric G-protein signaling pathway-Gq alpha and Go alpha mediated pathway | |||||
| Enkephalin releaseP00026:Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway | |||||
| Enkephalin release | |||||
| Opioid proenkephalin pathway | |||||
| Opioid proopiomelanocortin pathwayP00026:Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway | |||||
| Opioid prodynorphin pathway | |||||
| Pathway Interaction Database | IL4-mediated signaling events | ||||
| References | |||||
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