Drug Information
| Drug General Information | |||||
|---|---|---|---|---|---|
| Drug ID |
D05VSK
|
||||
| Former ID |
DNC010061
|
||||
| Drug Name |
ETHOXYCOUMARIN
|
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| Drug Type |
Small molecular drug
|
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| Indication | Discovery agent | Investigative | [1] | ||
| Structure |
|
Download2D MOL |
|||
| Formula |
C11H10O3
|
||||
| Canonical SMILES |
CCOC1=CC2=C(C=C1)C=CC(=O)O2
|
||||
| InChI |
1S/C11H10O3/c1-2-13-9-5-3-8-4-6-11(12)14-10(8)7-9/h3-7H,2H2,1H3
|
||||
| InChIKey |
LIFAQMGORKPVDH-UHFFFAOYSA-N
|
||||
| PubChem Compound ID | |||||
| Target and Pathway | |||||
| Target(s) | Carbonic anhydrase | Target Info | Inhibitor | [1] | |
| Carbonic anhydrase IX | Target Info | Inhibitor | [1] | ||
| Carbonic anhydrase XIV | Target Info | Inhibitor | [1] | ||
| Carbonic anhydrase XII | Target Info | Inhibitor | [1] | ||
| KEGG Pathway | Nitrogen metabolismhsa00910:Nitrogen metabolismhsa00910:Nitrogen metabolism | ||||
| NetPath Pathway | TGF_beta_Receptor Signaling Pathway | ||||
| Pathway Interaction Database | HIF-1-alpha transcription factor network | ||||
| Reactome | Regulation of gene expression by Hypoxia-inducible Factor | ||||
| Reversible hydration of carbon dioxideR-HSA-1475029:Reversible hydration of carbon dioxideR-HSA-1475029:Reversible hydration of carbon dioxide | |||||
| WikiPathways | Vitamin D Receptor Pathway | ||||
| Reversible Hydration of Carbon Dioxide | |||||
| Regulation of Hypoxia-inducible Factor (HIF) by OxygenWP2770:Reversible Hydration of Carbon DioxideWP2770:Reversible Hydration of Carbon Dioxide | |||||
| miR-targeted genes in muscle cell - TarBase | |||||
| miR-targeted genes in leukocytes - TarBase | |||||
| miR-targeted genes in epithelium - TarBase | |||||
| References | |||||
| REF 1 | J Med Chem. 2010 Jan 14;53(1):335-44.Deciphering the mechanism of carbonic anhydrase inhibition with coumarins and thiocoumarins. | ||||
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