Drug Information
Drug General Information | |||||
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Drug ID |
D04MSI
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Former ID |
DIB021052
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Drug Name |
threo-3-methylglutamate
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Synonyms |
(+/-)-threo-3-methylglutamic acid
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Drug Type |
Small molecular drug
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Indication | Discovery agent | Investigative | [467811] | ||
Structure |
Download2D MOL |
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Formula |
C6H11NO4
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InChI |
InChI=1S/C6H11NO4/c1-3(2-4(8)9)5(7)6(10)11/h3,5H,2,7H2,1H3,(H,8,9)(H,10,11)
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InChIKey |
FHJNAFIJPFGZRI-UHFFFAOYSA-N
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PubChem Compound ID | |||||
PubChem Substance ID | |||||
Target and Pathway | |||||
Target(s) | Excitatory amino acid transporter 2 | Target Info | Inhibitor | [534384] | |
Excitatory amino acid transporter 4 | Target Info | Inhibitor | [526025] | ||
WikiPathways | Amyotrophic lateral sclerosis (ALS) | ||||
References | |||||
Ref 526025 | Pharmacological characterization of threo-3-methylglutamic acid with excitatory amino acid transporters in native and recombinant systems. J Neurochem. 2001 Apr;77(2):550-7. | ||||
Ref 534384 | Contrasting modes of action of methylglutamate derivatives on the excitatory amino acid transporters, EAAT1 and EAAT2. Mol Pharmacol. 1997 May;51(5):809-15. |
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