Drug Information

Drug General Information
Drug ID
D04EZN
Former ID
DNC003326
Drug Name
Dimethylthiambutene
Drug Type
Small molecular drug
Indication Discovery agent Investigative [551393]
Structure
Download
2D MOL

3D MOL
Formula
C14H17NS2
Canonical SMILES
CC(C=C(C1=CC=CS1)C2=CC=CS2)N(C)C
InChI
1S/C14H17NS2/c1-11(15(2)3)10-12(13-6-4-8-16-13)14-7-5-9-17-14/h4-11H,1-3H3
InChIKey
CANBGVXYBPOLRR-UHFFFAOYSA-N
CAS Number
CAS 524-84-5
PubChem Compound ID
10668
PubChem Substance ID
8157707, 10525246, 15269141, 29229137, 46505069, 49866371, 78888081, 99319563, 104323933, 117404181, 126408806, 127596579, 134977985, 137147452, 160698162, 160964710, 179322802, 226413600, 241090595, 250099835
Target and Pathway
Target(s) Delta-type opioid receptor Target Info Agonist [551393]
Mu-type opioid receptor Target Info Agonist [551393]
KEGG Pathway cGMP-PKG signaling pathway
Sphingolipid signaling pathway
Neuroactive ligand-receptor interactionhsa04080:Neuroactive ligand-receptor interaction
Estrogen signaling pathway
Morphine addiction
NetPath Pathway TCR Signaling Pathway
PANTHER Pathway Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway
Heterotrimeric G-protein signaling pathway-Gq alpha and Go alpha mediated pathway
Enkephalin release
Opioid proenkephalin pathway
Opioid proopiomelanocortin pathwayP00026:Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway
Pathway Interaction Database IL4-mediated signaling events
Reactome Peptide ligand-binding receptors
G alpha (i) signalling eventsR-HSA-375276:Peptide ligand-binding receptors
G alpha (i) signalling events
WikiPathways GPCRs, Class A Rhodopsin-like
Peptide GPCRs
GPCR ligand binding
GPCR downstream signalingWP69:TCR Signaling Pathway
Opioid Signalling
GPCR downstream signaling
References
Ref 551393How many drug targets are there? Nat Rev Drug Discov. 2006 Dec;5(12):993-6.
Ref 551393How many drug targets are there? Nat Rev Drug Discov. 2006 Dec;5(12):993-6.

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