Drug Information
| Drug General Information | |||||
|---|---|---|---|---|---|
| Drug ID |
D03UHT
|
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| Former ID |
DNC007680
|
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| Drug Name |
MCL-458
|
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| Drug Type |
Small molecular drug
|
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| Indication | Discovery agent | Investigative | [528787] | ||
| Structure |
|
Download2D MOL |
|||
| Formula |
C22H28N2O2
|
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| Canonical SMILES |
C1CCC23CCN(C(C2C1)CC4=CC5=C(C=C34)OC(=O)N5)CC6CCC6
|
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| InChI |
1S/C22H28N2O2/c25-21-23-18-10-15-11-19-16-6-1-2-7-22(16,17(15)12-20(18)26-21)8-9-24(19)13-14-4-3-5-14/h10,12,14,16,19H,1-9,11,13H2,(H,23,25)/t16-,19+,22+/m0/s1
|
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| InChIKey |
PSLNEDDFOIXXGT-DKZVUGQWSA-N
|
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| PubChem Compound ID | |||||
| Target and Pathway | |||||
| Target(s) | Kappa-type opioid receptor | Target Info | Inhibitor | [528787] | |
| Delta-type opioid receptor | Target Info | Inhibitor | [528787] | ||
| Mu-type opioid receptor | Target Info | Inhibitor | [528787] | ||
| NetPath Pathway | TCR Signaling Pathway | ||||
| PANTHER Pathway | Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway | ||||
| Heterotrimeric G-protein signaling pathway-Gq alpha and Go alpha mediated pathway | |||||
| Opioid prodynorphin pathwayP00026:Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway | |||||
| Enkephalin release | |||||
| Opioid proenkephalin pathway | |||||
| Opioid proopiomelanocortin pathwayP00026:Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway | |||||
| Pathway Interaction Database | IL4-mediated signaling events | ||||
| References | |||||
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