Drug General Information
Drug ID
D03QZB
Former ID
DIB012733
Drug Name
F-1394
Drug Type
Small molecular drug
Indication Arteriosclerosis [ICD9: 440; ICD10:I70] Discontinued in Phase 1 [545396]
Company
Fujirebio KK
Structure
Download
2D MOL

3D MOL

Formula
C33H61N3O6
Canonical SMILES
C(=O)(N[C@@H]1[C@@H](OC(=O)CCNC(=O)[C@@H]2OC(OCC2(C)C)(<br />C)C)CCCC1)N(CC(C)(C)C)CCCCCCCCC
CAS Number
CAS 162490-89-3
PubChem Compound ID
Target and Pathway
Target(s) Liver carboxylesterase Target Info Modulator [526020]
KEGG Pathway Drug metabolism - other enzymes
Metabolic pathways
Pathway Interaction Database E2F transcription factor network
WikiPathways NRF2 pathway
Nuclear Receptors Meta-Pathway
Heroin metabolism
Irinotecan Pathway
Fluoropyrimidine Activity
Phase I biotransformations, non P450
References
Ref 545396Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800003109)
Ref 526020ACAT inhibitor F-1394 prevents intimal hyperplasia induced by balloon injury in rabbits. J Lipid Res. 2001 Apr;42(4):480-8.

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