Drug General Information
Drug ID
D03GLM
Former ID
DIB015633
Drug Name
BMS-210285
Drug Type
Small molecular drug
Indication Type 2 diabetes [ICD9: 250; ICD10:E11] Terminated [546852]
Company
Bristol-Myers Squibb Co
Structure
Download
2D MOL

3D MOL

Formula
C24H25ClF2N2O5S
Canonical SMILES
S(=O)(=O)(Nc1cc(ccc1O)[C@H](CN[C@@H](c1ccc(OC(F)F)cc1)C<br />c1cc(Cl)ccc1)O)C
CAS Number
CAS 344607-69-8
PubChem Compound ID
Target and Pathway
Target(s) Beta-3 adrenergic receptor Target Info Agonist [551898]
KEGG Pathway Calcium signaling pathway
cGMP-PKG signaling pathway
Neuroactive ligand-receptor interaction
Endocytosis
Salivary secretion
PANTHER Pathway Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway
Beta3 adrenergic receptor signaling pathway
Reactome Adrenoceptors
G alpha (s) signalling events
WikiPathways Monoamine GPCRs
Calcium Regulation in the Cardiac Cell
GPCRs, Class A Rhodopsin-like
GPCR ligand binding
GPCR downstream signaling
References
Ref 546852Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800010623)
Ref 551898CA patent application no. 509835, Nitrogen-containing heterocyclic derivatives, medicinal compositions containing the same and medicinal use thereof.

If You Find Any Error in Data or Bug in Web Service, Please Kindly Report It to Dr. Zhou and Dr. Zhang.