| Drug General Information |
| Drug ID |
D02DTR
|
| Former ID |
DNC004229
|
| Drug Name |
3-[3-(4-Imidazol-1-yl-phenoxy)-propyl]-pyridine
|
| Drug Type |
Small molecular drug
|
| Indication |
Discovery agent
|
Investigative |
[1]
|
|---|
| Structure |
|
Download
2D MOL
3D MOL
|
| Formula |
C17H17N3O
|
| Canonical SMILES |
C1=CC(=CN=C1)CCCOC2=CC=C(C=C2)N3C=CN=C3
|
| InChI |
1S/C17H17N3O/c1-3-15(13-18-9-1)4-2-12-21-17-7-5-16(6-8-17)20-11-10-19-14-20/h1,3,5-11,13-14H,2,4,12H2
|
| InChIKey |
GCRYIIOKZWQWIH-UHFFFAOYSA-N
|
| PubChem Compound ID |
|
| Target and Pathway |
| Target(s) |
Cytochrome P450 2D6 |
Target Info |
Inhibitor |
[1]
|
|---|
| Cytochrome P450 3A4 |
Target Info |
Inhibitor |
[1]
|
|
KEGG Pathway
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Metabolism of xenobiotics by cytochrome P450
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Drug metabolism - cytochrome P450
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Serotonergic synapsehsa00140:Steroid hormone biosynthesis
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Linoleic acid metabolism
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Retinol metabolism
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Drug metabolism - other enzymes
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Metabolic pathways
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Bile secretion
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Chemical carcinogenesis
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PathWhiz Pathway
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Caffeine Metabolism
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Retinol Metabolism
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Reactome
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XenobioticsR-HSA-211981:Xenobiotics
|
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Aflatoxin activation and detoxification
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WikiPathways
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Metapathway biotransformation
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Tamoxifen metabolism
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Oxidation by Cytochrome P450
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Vitamin D Receptor Pathway
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Aripiprazole Metabolic Pathway
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Fatty Acid Omega Oxidation
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Codeine and Morphine MetabolismWP702:Metapathway biotransformation
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Aflatoxin B1 metabolism
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Estrogen metabolism
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Benzo(a)pyrene metabolism
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Tryptophan metabolism
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Nuclear Receptors in Lipid Metabolism and Toxicity
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Nuclear Receptors Meta-Pathway
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Farnesoid X Receptor Pathway
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Felbamate Metabolism
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Lidocaine metabolism
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Nifedipine Activity
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Colchicine Metabolic Pathway
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Irinotecan Pathway
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Drug Induction of Bile Acid Pathway
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Codeine and Morphine Metabolism
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| References |
| REF 1 | Bioorg Med Chem Lett. 2004 Jan 19;14(2):333-6.Imidazole derivatives as new potent and selective 20-HETE synthase inhibitors. |
|---|
