Drug Information
Drug General Information | |||||
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Drug ID |
D01XOD
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Former ID |
DNC012025
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Drug Name |
ALPIDEM
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Drug Type |
Small molecular drug
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Indication | Anxiety disorder [ICD9: 300, 311; ICD10:F32, F40-F42] | Approved | [551871] | ||
Structure |
Download2D MOL |
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Formula |
C21H23Cl2N3O
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Canonical SMILES |
CCCN(CCC)C(=O)CC1=C(N=C2N1C=C(C=C2)Cl)C3=CC=C(C=C3)Cl
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InChI |
1S/C21H23Cl2N3O/c1-3-11-25(12-4-2)20(27)13-18-21(15-5-7-16(22)8-6-15)24-19-10-9-17(23)14-26(18)19/h5-10,14H,3-4,11-13H2,1-2H3
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InChIKey |
JRTIDHTUMYMPRU-UHFFFAOYSA-N
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CAS Number |
CAS 82626-01-5
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PubChem Compound ID | |||||
Target and Pathway | |||||
Target(s) | Gamma-aminobutyric acid receptor | Target Info | Inhibitor | [534470] | |
Peripheral-type benzodiazepine receptor | Target Info | Inhibitor | [529656] | ||
KEGG Pathway | Neuroactive ligand-receptor interaction | ||||
HTLV-I infection | |||||
References | |||||
Ref 529656 | J Med Chem. 2008 Sep 25;51(18):5798-806. Epub 2008 Aug 26.Anxiolytic-like effects of N,N-dialkyl-2-phenylindol-3-ylglyoxylamides by modulation of translocator protein promoting neurosteroid biosynthesis. | ||||
Ref 534470 | J Med Chem. 1997 Sep 12;40(19):3109-18.Synthesis and binding affinity of 2-phenylimidazo[1,2-alpha]pyridine derivatives for both central and peripheral benzodiazepine receptors. A new series of high-affinity and selective ligands for the peripheral type. |
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