Drug Information
Drug General Information | |||||
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Drug ID |
D01QRG
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Former ID |
DCL000284
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Drug Name |
RPR 200765A
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Drug Type |
Small molecular drug
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Indication | Rheumatoid arthritis [ICD9: 710-719, 714; ICD10:M05-M06] | Terminated | [547101] | ||
Company |
Aventis
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Structure |
Download2D MOL |
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Formula |
C24H25FN4O4
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Canonical SMILES |
CC1(COC(OC1)C2=NC(=C(N2)C3=CC=NC=C3)C4=CC=C(C=C4)F)C(=O<br />)N5CCOCC5
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InChI |
1S/C24H25FN4O4/c1-24(23(30)29-10-12-31-13-11-29)14-32-22(33-15-24)21-27-19(16-2-4-18(25)5-3-16)20(28-21)17-6-8-26-9-7-17/h2-9,22H,10-15H2,1H3,(H,27,28)
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InChIKey |
YEQUJOKCSZTBFS-UHFFFAOYSA-N
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CAS Number |
CAS 218160-20-4
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PubChem Compound ID | |||||
PubChem Substance ID | |||||
Target and Pathway | |||||
Target(s) | Prostaglandin G/H synthase 2 | Target Info | Inhibitor | [535126] | |
KEGG Pathway | Arachidonic acid metabolism | ||||
Metabolic pathways | |||||
NF-kappa B signaling pathway | |||||
VEGF signaling pathway | |||||
TNF signaling pathway | |||||
Retrograde endocannabinoid signaling | |||||
Serotonergic synapse | |||||
Ovarian steroidogenesis | |||||
Oxytocin signaling pathway | |||||
Regulation of lipolysis in adipocytes | |||||
Leishmaniasis | |||||
Pathways in cancer | |||||
Chemical carcinogenesis | |||||
MicroRNAs in cancer | |||||
Small cell lung cancer | |||||
PathWhiz Pathway | Arachidonic Acid Metabolism | ||||
References |
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