Drug Information
| Drug General Information | |||||
|---|---|---|---|---|---|
| Drug ID |
D00RDE
|
||||
| Former ID |
DNC010203
|
||||
| Drug Name |
4-(4'-N-Methylphenyl)diazenylbenzenesulfonamide
|
||||
| Drug Type |
Small molecular drug
|
||||
| Indication | Discovery agent | Investigative | [1] | ||
| Structure |
|
Download2D MOL |
|||
| Formula |
C13H14N4O2S
|
||||
| Canonical SMILES |
CNC1=CC=C(C=C1)N=NC2=CC=C(C=C2)S(=O)(=O)N
|
||||
| InChI |
1S/C13H14N4O2S/c1-15-10-2-4-11(5-3-10)16-17-12-6-8-13(9-7-12)20(14,18)19/h2-9,15H,1H3,(H2,14,18,19)
|
||||
| InChIKey |
RMLHDMTUTOMVIX-UHFFFAOYSA-N
|
||||
| PubChem Compound ID | |||||
| Target and Pathway | |||||
| Target(s) | Carbonic anhydrase XII | Target Info | Inhibitor | [1] | |
| Carbonic anhydrase IX | Target Info | Inhibitor | [1] | ||
| KEGG Pathway | Nitrogen metabolismhsa00910:Nitrogen metabolism | ||||
| NetPath Pathway | TGF_beta_Receptor Signaling Pathway | ||||
| Pathway Interaction Database | HIF-1-alpha transcription factor network | ||||
| Reactome | Reversible hydration of carbon dioxideR-HSA-1234158:Regulation of gene expression by Hypoxia-inducible Factor | ||||
| Reversible hydration of carbon dioxide | |||||
| WikiPathways | Reversible Hydration of Carbon Dioxide | ||||
| miR-targeted genes in muscle cell - TarBase | |||||
| miR-targeted genes in leukocytes - TarBase | |||||
| miR-targeted genes in epithelium - TarBaseWP2877:Vitamin D Receptor Pathway | |||||
| Regulation of Hypoxia-inducible Factor (HIF) by Oxygen | |||||
| References | |||||
| REF 1 | Bioorg Med Chem. 2009 Oct 15;17(20):7093-9. Epub 2009 Sep 6.Carbonic anhydrase inhibitors. Diazenylbenzenesulfonamides are potent and selective inhibitors of the tumor-associated isozymes IX and XIIover the cytosolic isoforms I and II. | ||||
If You Find Any Error in Data or Bug in Web Service, Please Kindly Report It to Dr. Zhou and Dr. Zhang.