Target Validation Information | |||||
---|---|---|---|---|---|
TTD ID | T51120 | ||||
Target Name | Thyroid peroxidase (TPO) | ||||
Type of Target |
Successful |
||||
Drug Potency against Target | Methimazole | Drug Info | IC50 = 100 microM | [1] | |
References | |||||
REF 1 | Methimazole and propylthiouracil increase cellular thyroid peroxidase activity and thyroid peroxidase mRNA in cultured porcine thyroid follicles. Thyroid. 1999 May;9(5):513-8. | ||||
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