| Target Validation Information | |||||
|---|---|---|---|---|---|
| TTD ID | T41201 | ||||
| Target Name | Dehydropeptidase I (DPEP1) | ||||
| Type of Target |
Successful |
||||
| Drug Potency against Target | Cilastatin | Drug Info | IC50 = 100 nM | [1] | |
| References | |||||
| REF 1 | The renal membrane dipeptidase (dehydropeptidase I) inhibitor, cilastatin, inhibits the bacterial metallo-beta-lactamase enzyme CphA. Antimicrob Agents Chemother. 1995 Jul;39(7):1629-31. | ||||
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