Target Validation Information | |||||
---|---|---|---|---|---|
TTD ID | T39977 | ||||
Target Name | Macrophage migration inhibitory factor (MIF) | ||||
Type of Target |
Clinical trial |
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Action against Disease Model | COR100140 | Drug Info | Chemical inhibitors of MIF enzymatic activity:In vitro activity, COR100140 inhibited IL-1-induced synovial fibroblast proliferation of RA patients and IL-1-induced fibroblast expression of COX-2. | [1] | |
References | |||||
REF 1 | Macrophage migration inhibitory factor is a determinant of hypoxia-induced apoptosis in colon cancer cell lines. Clin Cancer Res. 2005 Oct 15;11(20):7264-72. | ||||
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