Target Validation Information
TTD ID T39977
Target Name Macrophage migration inhibitory factor (MIF)
Type of Target
Clinical trial
Action against Disease Model COR100140 Drug Info Chemical inhibitors of MIF enzymatic activity:In vitro activity, COR100140 inhibited IL-1-induced synovial fibroblast proliferation of RA patients and IL-1-induced fibroblast expression of COX-2. [1]
References
REF 1 Macrophage migration inhibitory factor is a determinant of hypoxia-induced apoptosis in colon cancer cell lines. Clin Cancer Res. 2005 Oct 15;11(20):7264-72.

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