| Target Validation Information | |||||
|---|---|---|---|---|---|
| TTD ID | T38301 | ||||
| Target Name | Ribonucleoside-diphosphate reductase M2 (RRM2) | ||||
| Type of Target |
Successful |
||||
| Drug Potency against Target | Motexafin gadolinium | Drug Info | IC50 = 6 microM | [1] | |
| References | |||||
| REF 1 | Motexafin gadolinium, a tumor-selective drug targeting thioredoxin reductase and ribonucleotide reductase. J Biol Chem. 2006 Apr 21;281(16):10691-7. | ||||
If You Find Any Error in Data or Bug in Web Service, Please Kindly Report It to Dr. Zhou and Dr. Zhang.