| Target Validation Information | |||||
|---|---|---|---|---|---|
| TTD ID | T35445 | ||||
| Target Name | Mothers against decapentaplegic homolog 3 (SMAD3) | ||||
| Type of Target |
Preclinical |
||||
| Drug Potency against Target | ELLAGIC ACID | Drug Info | IC50 = 142 nM | [1] | |
| FLUORESCEIN | Drug Info | IC50 = 4890 nM | [1] | ||
| GNF-PF-2272 | Drug Info | IC50 = 38 nM | [1] | ||
| References | |||||
| REF 1 | In silico identification and biochemical evaluation of novel inhibitors of NRH:quinone oxidoreductase 2 (NQO2). Bioorg Med Chem Lett. 2010 Dec 15;20(24):7331-6. | ||||
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