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| Target General Information |
Top |
| Target ID |
T96256 |
Target Info
|
| Target Name |
Cytovillin (EZR) |
| Synonyms |
p81; Villin-2; VIL2 |
| Target Type |
Literature-reported Target |
| Gene Name |
EZR |
| UniProt ID |
|
| Target Interacting Proteins |
Top |
| Hydrolysis-driven transporters |
[+] 1 Hydrolysis-driven transporters |
+ |
| Interacting Target Name |
cAMP-dependent chloride channel (CFTR) |
Successful Target |
Interacting Protein Info
|
| UniProt ID |
|
| Synonyms |
Cystic fibrosis transmembrane conductance regulator; Channel conductancecontrolling ATPase; cAMP-dependent chloride channel; cAMPdependent chloride channel; ATP-binding cassette sub-family C member 7; ATPbinding cassette subfamily C member 7; ABCC7 |
| Evidence Score (E-score) |
2 Experimental Evidences |
+ |
| 1 |
Affinity Capture-MS |
[1] |
| 2 |
Affinity Capture-Western |
[2] |
| Other proteins |
[+] 1 Other proteins |
+ |
| Interacting Target Name |
Epithelial cadherin (CDH1) |
Literature-reported Target |
Interacting Protein Info
|
| UniProt ID |
|
| Synonyms |
Uvomorulin; UVO; E-cadherin gene; E-cadherin; CDHE; CD324; CAM 120/80; Cadherin-1 |
| Evidence Score (E-score) |
2 Experimental Evidences |
+ |
| 1 |
Affinity Capture-Western |
[3] |
| 2 |
Proximity Label-MS |
[4] |
| References |
Top |
| REF 1 |
508 CFTR interactome remodelling promotes rescue of cystic fibrosis. Nature. 2015 Dec 24;528(7583):510-6.
|
| REF 2 |
E3KARP mediates the association of ezrin and protein kinase A with the cystic fibrosis transmembrane conductance regulator in airway cells. J Biol Chem. 2000 Sep 22;275(38):29539-46.
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| REF 3 |
Ezrin regulates cell-cell and cell-matrix adhesion, a possible role with E-cadherin/beta-catenin. J Cell Sci. 1999 Sep;112 Pt 18:3081-90.
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| REF 4 |
E-cadherin interactome complexity and robustness resolved by quantitative proteomics. Sci Signal. 2014 Dec 2;7(354):rs7.
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