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| Target General Information |
Top |
| Target ID |
T23995 |
Target Info
|
| Target Name |
Protein kinase C theta (PRKCQ) |
| Synonyms |
Protein kinase C theta type; PRKCT; NPKC-theta |
| Target Type |
Clinical trial Target |
| Gene Name |
PRKCQ |
| Biochemical Class |
Kinase |
| UniProt ID |
|
| Target Interacting Proteins |
Top |
| Other proteins |
[+] 1 Other proteins |
+ |
| Interacting Protein Name |
Caspase recruitment domain-containing protein 11 (CARD11) |
Interacting Protein |
Interacting Protein Info
|
| UniProt ID |
|
| Synonyms |
BENTA; BIMP3; CARMA1; IMD11; PPBL |
| Evidence Score (E-score) |
2 Experimental Evidences |
+ |
| 1 |
Affinity Capture-Western |
[1] |
| 2 |
Biochemical Activity |
[2] |
| References |
Top |
| REF 1 |
NF-kappaB activation in T cells requires discrete control of IkappaB kinase alpha/beta (IKKalpha/beta) phosphorylation and IKKgamma ubiquitination by the ADAP adapter protein. J Biol Chem. 2010 Apr 9;285(15):11100-5.
|
| REF 2 |
Phosphorylation of the CARMA1 linker controls NF-kappaB activation. Immunity. 2005 Dec;23(6):561-74.
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