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| Target General Information |
Top |
| Target ID |
T12581 |
Target Info
|
| Target Name |
IP3 receptor isoform 3 (ITPR3) |
| Synonyms |
Type 3 inositol 1,4,5-trisphosphate receptor; Type 3 InsP3 receptor; InsP3R3; Inositol 1,4,5-trisphosphate receptor type 3; IP3R 3 |
| Target Type |
Literature-reported Target |
| Gene Name |
ITPR3 |
| Biochemical Class |
Ryanodine-inositol triphosphate calcium channel |
| UniProt ID |
|
| Target Interacting Proteins |
Top |
| Alpha-type channels |
[+] 1 Alpha-type channels |
+ |
| Interacting Target Name |
Short transient receptor potential channel 1 (TRPC1) |
Literature-reported Target |
Interacting Protein Info
|
| UniProt ID |
|
| Synonyms |
TrpC1; TRP-1; Transient receptor protein 1 |
| Evidence Score (E-score) |
2 Experimental Evidences |
+ |
| 1 |
Affinity Capture-Western |
[1] |
| 2 |
Reconstituted Complex |
[2] |
| References |
Top |
| REF 1 |
Caveolin-1 scaffold domain interacts with TRPC1 and IP3R3 to regulate Ca2+ store release-induced Ca2+ entry in endothelial cells. Am J Physiol Cell Physiol. 2009 Mar;296(3):C403-13.
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| REF 2 |
Identification of common binding sites for calmodulin and inositol 1,4,5-trisphosphate receptors on the carboxyl termini of trp channels. J Biol Chem. 2001 Jun 15;276(24):21303-10.
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