Target Regulator(s) Information (MicroRNA)

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Target General Information
The microRNAs (miRNAs) Regulating This Target
References
Target General Information  Top
Target ID T77645 Target Info
Target Name TRAIL receptor 1 (TRAIL-R1)
Synonyms Tumor necrosis factor receptor superfamily member 10A; TRAILR1; TNF-related apoptosis-inducing ligand receptor 1; Death receptor 4; DR4; CD261; APO2
Target Type Clinical trial Target
Gene Name TNFRSF10A
Biochemical Class Cytokine receptor
UniProt ID
O00220
The microRNAs (miRNAs) Regulating This Target  Top
miRNA Mature ID hsa-miR-106b-5p miRNA Info
miRNA Mature AC
MIMAT0000680
Sequence uaaagugcugacagugcagau
miRNA Species Homo sapiens
Evidence Score (E-score) 1 +
1 Luciferase Reporter Assay; Western Blot [1]
Representative Target(s) Regulated by This miRNA Amyloid beta A4 protein (APP) Target Info
A4_HUMAN
Apoptosis mediating surface antigen FAS (FAS) Target Info
TNR6_HUMAN
References  Top
REF 1 MiR-106b inhibitors sensitize TRAIL-induced apoptosis in hepatocellular carcinoma through increase of death receptor 4. Oncotarget. 2017 Jun 27;8(26):41921-41931.

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