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Target General Information |
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Target ID |
T62912 |
Target Info
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Target Name |
Corticotropin-lipotropin (POMC) |
Synonyms |
Pro-opiomelanocortin |
Target Type |
Literature-reported Target |
Gene Name |
POMC |
UniProt ID |
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The microRNAs (miRNAs) Regulating This Target |
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miRNA Mature ID |
hsa-miR-488-3p |
miRNA Info
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miRNA Mature AC |
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Sequence |
uugaaaggcuauuucuugguc
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miRNA Species |
Homo sapiens |
Regulation Mechanism |
miR-488 reduced the luciferase activity of the pro-opiomelanocortin POMC constructs. |
[2] |
Evidence Score (E-score) |
2 |
+ |
1 |
Literature Reported |
[1] |
2 |
Luciferase Reporter Assay |
[2] |
Representative Target(s) Regulated by This miRNA |
Corticotropin-lipotropin (POMC)
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Target Info
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References |
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REF 1 |
miR-488 determines coat pigmentation by down-regulating the pigment-producing gene pro-opiomelanocortin. Cell Mol Biol (Noisy-le-grand). 2016 Oct 31;62(12):37-43.
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REF 2 |
Human microRNAs miR-22, miR-138-2, miR-148a, and miR-488 are associated with panic disorder and regulate several anxiety candidate genes and related pathways. Biol Psychiatry. 2011 Mar 15;69(6):526-33.
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