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| Target General Information |
Top |
| Target ID |
T56108 |
Target Info
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| Target Name |
Tripartite motif-containing 24 (TRIM24) |
| Synonyms |
Tripartite motif-containing protein 24; Transcription intermediary factor 1-alpha; TIF1A; TIF1-alpha; TIF1; RNF82; RING-type E3 ubiquitin transferase TIF1-alpha; RING finger protein 82; E3 ubiquitin-protein ligase TRIM24 |
| Target Type |
Literature-reported Target |
| Gene Name |
TRIM24 |
| Biochemical Class |
Acyltransferase |
| UniProt ID |
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| The microRNAs (miRNAs) Regulating This Target |
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| miRNA Mature ID |
hsa-miR-511-5p |
miRNA Info
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| miRNA Mature AC |
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| Sequence |
gugucuuuugcucugcaguca
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| miRNA Species |
Homo sapiens |
| Regulation Mechanism |
Tumor suppressive role of miR-511 in gastric cancer by suppressing TRIM24, suggesting that this novel miR-511/TRIM24 axis is critical in the control of gastric cancer tumorigenesis. |
[1] |
| Evidence Score (E-score) |
1 |
+ |
| 1 |
Luciferase Reporter Assay; Western Blot |
[1] |
| Representative Target(s) Regulated by This miRNA |
FK506-binding protein 5 (FKBP5)
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Target Info
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Liver organic anion transporter 1 (SLCO1B1)
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Target Info
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| References |
Top |
| REF 1 |
Regulation of TRIM24 by miR-511 modulates cell proliferation in gastric cancer. J Exp Clin Cancer Res. 2017 Jan 23;36(1):17.
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