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Target General Information |
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Target ID |
T55922 |
Target Info
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Target Name |
S-adenosylmethionine decarboxylase proenzyme (AMD1) |
Synonyms |
SamDC; S-adenosylmethioninedecarboxylase; AdoMetDC; AMD |
Target Type |
Successful Target |
Gene Name |
AMD1 |
Biochemical Class |
Carbon-carbon lyase |
UniProt ID |
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The microRNAs (miRNAs) Regulating This Target |
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miRNA Mature ID |
hsa-miR-762 |
miRNA Info
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miRNA Mature AC |
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Sequence |
ggggcuggggccggggccgagc
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miRNA Species |
Homo sapiens |
Regulation Mechanism |
AMD1 translational down-regulation is mediated by miR-762. |
[1] |
Evidence Score (E-score) |
1 |
+ |
1 |
Luciferase Reporter Assay |
[1] |
Representative Target(s) Regulated by This miRNA |
S-adenosylmethionine decarboxylase proenzyme (AMD1)
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Target Info
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References |
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REF 1 |
AMD1 is essential for ESC self-renewal and is translationally down-regulated on differentiation to neural precursor cells. Genes Dev. 2012 Mar 1;26(5):461-73.
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