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Target General Information |
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Target ID |
T34562 |
Target Info
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Target Name |
Serum paraoxonase/arylesterase 1 (PON1) |
Synonyms |
Serum paraoxonase; Serum aryldialkylphosphatase 1; Serum aryldiakylphosphatase 1; PON 1; PON; K-45; Aromatic esterase 1; A-esterase 1 |
Target Type |
Literature-reported Target |
Gene Name |
PON1 |
Biochemical Class |
Carboxylic ester hydrolase |
UniProt ID |
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The microRNAs (miRNAs) Regulating This Target |
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miRNA Mature ID |
hsa-miR-616-3p |
miRNA Info
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miRNA Mature AC |
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Sequence |
agucauuggaggguuugagcag
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miRNA Species |
Homo sapiens |
Regulation Mechanism |
miR-616 binding to the PON1 3'UTR. |
[1] |
Evidence Score (E-score) |
1 |
+ |
1 |
Luciferase Reporter Assay |
[1] |
Representative Target(s) Regulated by This miRNA |
Serum paraoxonase/arylesterase 1 (PON1)
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Target Info
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References |
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REF 1 |
A functional polymorphism of PON1 interferes with microRNA binding to increase the risk of ischemic stroke and carotid atherosclerosis. Atherosclerosis. 2013 May;228(1):161-7.
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