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Target General Information |
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Target ID |
T22978 |
Target Info
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Target Name |
Transforming growth factor beta 3 (TGFB3) |
Synonyms |
Transforming growth factor beta-3 proprotein; Transforming growth factor beta-3; TGF-beta-3; Latency-associated peptide |
Target Type |
Clinical trial Target |
Gene Name |
TGFB3 |
Biochemical Class |
Growth factor |
UniProt ID |
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The microRNAs (miRNAs) Regulating This Target |
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miRNA Mature ID |
hsa-miR-29a-3p |
miRNA Info
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miRNA Mature AC |
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Sequence |
uagcaccaucugaaaucgguua
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miRNA Species |
Homo sapiens |
Regulation Mechanism |
miR-29 targets TGFB3 and TGFB3 was significantly upregulated in DM1 patients. |
[1] |
Evidence Score (E-score) |
1 |
+ |
1 |
qRT-PCR |
[1] |
Representative Target(s) Regulated by This miRNA |
Apoptosis regulator Bcl-2 (BCL-2)
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Target Info
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Aryl hydrocarbon receptor (AHR)
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Target Info
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References |
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REF 1 |
Dysregulation and cellular mislocalization of specific miRNAs in myotonic dystrophy type 1. Neuromuscul Disord. 2011 Feb;21(2):81-8.
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