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Target General Information |
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Target ID |
T03500 |
Target Info
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Target Name |
Matrix metalloproteinase-12 (MMP-12) |
Synonyms |
Macrophage metalloelastase; Macrophage elastase; MME; ME; HME |
Target Type |
Clinical trial Target |
Gene Name |
MMP12 |
Biochemical Class |
Peptidase |
UniProt ID |
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The microRNAs (miRNAs) Regulating This Target |
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miRNA Mature ID |
hsa-miR-145-5p |
miRNA Info
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miRNA Mature AC |
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Sequence |
guccaguuuucccaggaaucccu
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miRNA Species |
Homo sapiens |
Evidence Score (E-score) |
1 |
+ |
1 |
Reporter Assay |
[1] |
Representative Target(s) Regulated by This miRNA |
A proliferation-inducing ligand (APRIL)
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Target Info
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Alkaline phosphatase (ALPPL2)
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Target Info
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References |
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REF 1 |
miR-145, miR-133a and miR-133b: Tumor-suppressive miRNAs target FSCN1 in esophageal squamous cell carcinoma. Int J Cancer. 2010 Dec 15;127(12):2804-14.
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