Target Regulator(s) Information (MicroRNA)

Content Navigation (  All   None )                                      
Target General Information
The microRNAs (miRNAs) Regulating This Target
References
Target General Information  Top
Target ID T02808 Target Info
Target Name Interferon-beta (IFNB1)
Synonyms Interferon beta; IFNbeta; IFNB; IFN-beta; IFB; Fibroblast interferon
Target Type Successful Target
Gene Name IFNB1
Biochemical Class Cytokine: interferon
UniProt ID
P01574
The microRNAs (miRNAs) Regulating This Target  Top
miRNA Mature ID hsa-miR-145-5p miRNA Info
miRNA Mature AC
MIMAT0000437
Sequence guccaguuuucccaggaaucccu
miRNA Species Homo sapiens
Regulation Mechanism miR-145 mimics silence reporters containing IFN-b 3'UTR sequences. [1]
Evidence Score (E-score) 2 +
1 ELISA; Luciferase Reporter Assay [1]
2 Luciferase Reporter Assay; qPCR [2]
Representative Target(s) Regulated by This miRNA A proliferation-inducing ligand (APRIL) Target Info
TNF13_HUMAN
Alkaline phosphatase (ALPPL2) Target Info
PPBN_HUMAN
miRNA Mature ID hsa-let-7b-5p miRNA Info
miRNA Mature AC
MIMAT0000063
Sequence ugagguaguagguugugugguu
miRNA Species Homo sapiens
Regulation Mechanism Let-7b mimics silence reporters containing IFN-b 3'UTR sequences. [1]
Evidence Score (E-score) 1 +
1 ELISA; Luciferase Reporter Assay [1]
Representative Target(s) Regulated by This miRNA Activin receptor-like kinase 2 (ALK-2) Target Info
ACVR1_HUMAN
CDK inhibitor 1B p27Kip1 (CDKN1B) Target Info
CDN1B_HUMAN
miRNA Mature ID hsa-miR-34a-5p miRNA Info
miRNA Mature AC
MIMAT0000255
Sequence uggcagugucuuagcugguugu
miRNA Species Homo sapiens
Regulation Mechanism miR-34a mimics silence reporters containing IFN-b 3'UTR sequences. [1]
Evidence Score (E-score) 1 +
1 ELISA; Luciferase Reporter Assay [1]
Representative Target(s) Regulated by This miRNA Amphiregulin (AREG) Target Info
AREG_HUMAN
Androgen receptor (AR) Target Info
ANDR_HUMAN
References  Top
REF 1 MicroRNA regulation of IFN-beta protein expression: rapid and sensitive modulation of the innate immune response. J Immunol. 2010 Mar 1;184(5):2369-76.
REF 2 MicroRNA-145 regulates human corneal epithelial differentiation. PLoS One. 2011;6(6):e21249.

If You Find Any Error in Data or Bug in Web Service, Please Kindly Report It to Dr. Zhou and Dr. Zhang.