Binding Site Information of Target
Target General Information | Top | ||||
---|---|---|---|---|---|
Target ID | T53890 | Target Info | |||
Target Name | Gankyrin (PSMD10) | ||||
Synonyms | p28(GANK); 26S proteasome regulatory subunit p28; 26S proteasome non-ATPase regulatory subunit 10 | ||||
Target Type | Literature-reported Target | ||||
Gene Name | PSMD10 | ||||
UniProt ID |
Drug Binding Sites of Target | Top | |||||
---|---|---|---|---|---|---|
Ligand Name: Urea | Ligand Info | |||||
Structure Description | Snapshots of Human PSMD10(Gankyrin) unfolding by urea: 1 hour incubation | PDB:7VXW | ||||
Method | X-ray diffraction | Resolution | 2.22 Å | Mutation | No | [1] |
PDB Sequence |
GCVSNLMVCN
12 LAYSGKLEEL22 KESILADKSL32 ATRTDQDSRT42 ALHWACSAGH52 TEIVEFLLQL 62 GVPVNDKDDA72 GWSPLHIAAS82 AGRDEIVKAL92 LGKGAQVNAV102 NQNGCTPLHY 112 AASKNRHEIA122 VMLLEGGANP132 DAKDHYEATA142 MHRAAAKGNL152 KMIHILLYYK 162 ASTNIQDTEG172 NTPLHLACDE182 ERVEEAKLLV192 SQGASIYIEN202 KEEKTPLQVA 212 KGGLGLILKR222 MVEG
|
|||||
|
||||||
Click to View More Binding Site Information of This Target and Ligand Pair |
References | Top | ||||
---|---|---|---|---|---|
REF 1 | Snapshots of urea-induced early structural changes and unfolding of an ankyrin repeat protein at atomic resolution. Protein Sci. 2022 Dec;31(12):e4515. |
If You Find Any Error in Data or Bug in Web Service, Please Kindly Report It to Dr. Zhou and Dr. Zhang.