Binding Site Information of Target
Target General Information | Top | ||||
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Target ID | T42976 | Target Info | |||
Target Name | Glutathione S-transferase A3 (GSTA3) | ||||
Synonyms | Glutathione S-transferase A3-3; GST class-alpha member 3 | ||||
Target Type | Literature-reported Target | ||||
Gene Name | GSTA3 | ||||
UniProt ID |
Drug Binding Sites of Target | Top | |||||
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Ligand Name: Glutathione | Ligand Info | |||||
Structure Description | Glutathione transferase A3-3 in complex with glutathione and delta-4- androstene-3-17-dione | PDB:2VCV | ||||
Method | X-ray diffraction | Resolution | 1.80 Å | Mutation | No | [1] |
PDB Sequence |
KPKLHYFNGR
13 GRMEPIRWLL23 AAAGVEFEEK33 FIGSAEDLGK43 LRNDGSLMFQ53 QVPMVEIDGM 63 KLVQTRAILN73 YIASKYNLYG83 KDIKERALID93 MYTEGMADLN103 EMILLLPLCR 113 PEEKDAKIAL123 IKEKTKSRYF133 PAFEKVLQSH143 GQDYLVGNKL153 SRADISLVEL 163 LYYVEELDSS173 LISNFPLLKA183 LKTRISNLPT193 VKKFLQPGSP203 RKPPADAKAL 213 EEARKIFRF
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Click to View More Binding Site Information of This Target and Ligand Pair | ||||||
Ligand Name: 4-ANDROSTENE-3-17-DIONE | Ligand Info | |||||
Structure Description | Glutathione transferase A3-3 in complex with glutathione and delta-4- androstene-3-17-dione | PDB:2VCV | ||||
Method | X-ray diffraction | Resolution | 1.80 Å | Mutation | No | [1] |
PDB Sequence |
KPKLHYFNGR
13 GRMEPIRWLL23 AAAGVEFEEK33 FIGSAEDLGK43 LRNDGSLMFQ53 QVPMVEIDGM 63 KLVQTRAILN73 YIASKYNLYG83 KDIKERALID93 MYTEGMADLN103 EMILLLPLCR 113 PEEKDAKIAL123 IKEKTKSRYF133 PAFEKVLQSH143 GQDYLVGNKL153 SRADISLVEL 163 LYYVEELDSS173 LISNFPLLKA183 LKTRISNLPT193 VKKFLQPGSP203 RKPPADAKAL 213 EEARKIFRF
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References | Top | ||||
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REF 1 | Structural basis for featuring of steroid isomerase activity in alpha class glutathione transferases. J Mol Biol. 2010 Mar 19;397(1):332-40. |
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