Binding Site Information of Target
| Target General Information | Top | ||||
|---|---|---|---|---|---|
| Target ID | T07466 | Target Info | |||
| Target Name | Bacterial Glycosyltransferase MurG (Bact murG) | ||||
| Synonyms | Undecaprenyl-PP-MurNAc-pentapeptide-UDPGlcNAc GlcNAc transferase; MurG | ||||
| Target Type | Literature-reported Target | ||||
| Gene Name | Bact murG | ||||
| Biochemical Class | Hexosyltransferase | ||||
| UniProt ID | |||||
| Drug Binding Sites of Target | Top | |||||
|---|---|---|---|---|---|---|
| Ligand Name: Uridine-Diphosphate-N-Acetylglucosamine | Ligand Info | |||||
| Structure Description | CRYSTAL STRUCTURE OF MURG:GLCNAC COMPLEX | PDB:1NLM | ||||
| Method | X-ray diffraction | Resolution | 2.50 Å | Mutation | No | [1] |
| PDB Sequence |
KRLMVMAGGT
16 GGHVFPGLAV26 AHHLMAQGWQ36 VRWLGTADRM46 EADLVPKHGI56 EIDFIRISGL 66 RGKGIKALIA76 APLRIFNAWR86 QARAIMKAYK96 PDVVLGMGGY106 VSGPGGLAAW 116 SLGIPVVLHE126 QNGIAGLTNK136 WLAKIATKVM146 QAFPGAFPNA156 EVVGNPVRTD 166 VLALPLPQQR176 LAGREGPVRV186 LVVGGSQGAR196 ILNQTMPQVA206 AKLGDSVTIW 216 HQSGKGSQQS226 VEQAYAEAGQ236 PQHKVTEFID246 DMAAAYAWAD256 VVVCRSGALT 266 VSEIAAAGLP276 ALFVPFQHKD286 RQQYWNALPL296 EKAGAAKIIE306 QPQLSVDAVA 316 NTLAGWSRET326 LLTMAERARA336 ASIPDATERV346 ANEVSRVARA356 |
|||||
|
|
GLY18
3.275
ASN128
2.644
ARG164
2.723
VAL189
3.777
GLY191
3.589
SER192
3.423
GLN193
4.539
GLN218
3.167
PHE244
3.364
ILE245
3.032
ASP246
4.963
MET248
3.416
|
|||||
| References | Top | ||||
|---|---|---|---|---|---|
| REF 1 | Crystal structure of the MurG:UDP-GlcNAc complex reveals common structural principles of a superfamily of glycosyltransferases. Proc Natl Acad Sci U S A. 2003 Feb 4;100(3):845-9. | ||||
If You Find Any Error in Data or Bug in Web Service, Please Kindly Report It to Dr. Zhou and Dr. Zhang.