Target Poor or Non Binder(s) Information
| Target General Information | Top | ||||
|---|---|---|---|---|---|
| Target ID | T96685 | Target Info | |||
| Target Name | Hexokinase-2 (HK2) | ||||
| Synonyms |
Muscle form hexokinase; Hexokinase type II; HK II
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| Target Type | Clinical trial Target | ||||
| Gene Name | HK2 | ||||
| Biochemical Class | Hexokinase family | ||||
| UniProt ID | |||||
| Non Binders of This Target (in total, 2 non binders) | Download | Top | |||
|---|---|---|---|---|---|
| Compound Name |
CID 67974101
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|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3805806; SCHEMBL9937889; BDBM50169020
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| Activity |
IC50 > 400000 nM
|
[1] | |||
| Compound Name |
(E)-3-(3,4-Dichlorophenyl)-N-[(3S,4R,5S,6R)-4,5-dihydroxy-6-(hydroxymethyl)oxan-3-yl]prop-2-enamide
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|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3805752; BDBM50169022
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| Activity |
IC50 > 400000 nM
|
[1] | |||
| References | Top | ||||
|---|---|---|---|---|---|
| REF 1 | Discovery of a Novel 2,6-Disubstituted Glucosamine Series of Potent and Selective Hexokinase 2 Inhibitors. ACS Med Chem Lett. 2015 Dec 28;7(3):217-22. | ||||
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