Target Poor or Non Binder(s) Information
| Target General Information | Top | ||||
|---|---|---|---|---|---|
| Target ID | T89846 | Target Info | |||
| Target Name | Herpesvirus DNA polymerase (KSHV DNAP) | ||||
| Target Type | Discontinued Target | ||||
| Gene Name | NO-GeName | ||||
| UniProt ID | |||||
| Poor Binders of This Target (in total, 8 binders) | Download | Top | |||
|---|---|---|---|---|---|
| Compound Name |
Phenoxy(sodiooxy)phosphinylformic acid phenyl ester
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|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL273301; sodium phenyl phenoxycarbonylphosphonate; SCHEMBL10938364
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|
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| Activity |
IC50 = 52000 nM
|
[1] | |||
| Compound Name |
Sodium 4-methylphenyl phenoxycarbonylphosphonate
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|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL328911; SCHEMBL10934541
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|
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| Activity |
IC50 = 54000 nM
|
[1] | |||
| Compound Name |
Disodium;[2,3-dihydro-1H-inden-5-yloxy(oxido)phosphoryl]formate
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|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL424242
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|
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| Activity |
IC50 = 73000 nM
|
[1] | |||
| Compound Name |
Disodium oxido(phenoxy)phosphinecarboxylate oxide
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|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL91834
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|
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| Activity |
IC50 = 79000 nM
|
[1] | |||
| Compound Name |
Disodium;[(4-methylphenoxy)-oxidophosphoryl]formate
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|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL90955
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|
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| Activity |
IC50 = 87000 nM
|
[1] | |||
| Compound Name |
Disodium;[(4-methoxyphenoxy)-oxidophosphoryl]formate
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|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL90954
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|
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| Activity |
IC50 = 90000 nM
|
[1] | |||
| Compound Name |
Phenyl [ethoxy-(4-methoxyphenoxy)phosphoryl]formate
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|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL91431; Phosphinecarboxylic acid, ethoxy(4-methoxyphenoxy)-, phenyl ester, oxide; phenyl (4-methoxyphenoxy)(ethoxy)phosphinecarboxylate oxide; SCHEMBL10937328; DTXSID80993087; BDBM50027565; Phenyl ethoxy(4-methoxyphenoxy)oxo-lambda~5~-phosphanecarboxylate
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|
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| Activity |
IC50 = 97000 nM
|
[1] | |||
| Compound Name |
Sodium ethyl (4-methoxyphenoxy)carbonylphosphonate
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|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL91401
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|
||||
| Activity |
IC50 = 165000 nM
|
[1] | |||
| Click to Show/Hide the Information of All Poor Binders | |||||
| Non Binders of This Target (in total, 44 non binders) | Download | Top | |||
|---|---|---|---|---|---|
| Compound Name |
Disodium;(4-chlorophenyl) phosphonatoformate
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|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL92550; SCHEMBL10935446
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|
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| Activity |
IC50 = 250000 nM
|
[1] | |||
| Compound Name |
Disodium (ethoxyoxydophosphanyl)formate
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|
Investigative | Compound Info | ||
| Synonyms |
Disodium (ethyl phosphono)formate; FOSCARNET IMPURITY B; Phosphinecarboxylic acid, ethoxyhydroxy-, oxide; CHEMBL91883; UNII-F90H9GL03I; disodium ethoxy(oxido)phosphinecarboxylate oxide; F90H9GL03I; SCHEMBL11601322; MFCD25977182; disodium;[ethoxy(oxido)phosphoryl]formate; Q27277822
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|
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| Activity |
IC50 > 500000 nM
|
[1] | |||
| Compound Name |
Sodium 2,6-dimethylphenyl methoxycarbonylphosphonate
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|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL327318; SCHEMBL10889196
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|
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| Activity |
IC50 > 500000 nM
|
[1] | |||
| Compound Name |
Disodium phenoxycarbonylphosphonate
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|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL91174; SCHEMBL10938296
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|
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| Activity |
IC50 > 500000 nM
|
[1] | |||
| Compound Name |
Disodium butoxycarbonylphosphonate
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|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL90982; SCHEMBL11147279
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|
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| Activity |
IC50 > 500000 nM
|
[1] | |||
| Compound Name |
Phosphinecarboxylic acid, hydroxymethoxy-, oxide, disodium salt
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|
Investigative | Compound Info | ||
| Synonyms |
Hydroxymethoxyphosphinecarboxylic acid oxide, disodium salt; CHEMBL90964; disodium methoxy(oxido)phosphinecarboxylate oxide; disodium [methoxy(oxido)phosphoryl]formate; SCHEMBL843597; CTK5A4376; DTXSID00204521; A831481; disodium [methoxy(oxidanidyl)phosphoryl]methanoate
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|
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| Activity |
IC50 > 500000 nM
|
[1] | |||
| Compound Name |
Disodium (benzyloxy)carbonylphosphonate
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|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL90200; SCHEMBL10888667
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|
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| Activity |
IC50 > 500000 nM
|
[1] | |||
| Compound Name |
Phosphinecarboxylic acid, dibutoxy-, methyl ester, oxide
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|
Investigative | Compound Info | ||
| Synonyms |
methyl dibutoxyphosphorylformate; CHEMBL90437; methyl dibutoxyphosphinecarboxylate oxide; SCHEMBL2240082; DTXSID70222636; di-n-butyl methoxycarbonylphosphonate; BDBM50027569; di-n-butyl (methoxycarbonyl)phosphonate
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|
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| Activity |
IC50 > 500000 nM
|
[1] | |||
| Compound Name |
Phosphinecarboxylic acid, dimethoxy-, butyl ester, oxide
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|
Investigative | Compound Info | ||
| Synonyms |
butyl dimethoxyphosphorylformate; CHEMBL90949; Dimethyl n-butoxycarbonylphosphonate; butyl dimethoxyphosphinecarboxylate oxide; SCHEMBL2240121; DTXSID50222634; BDBM50027541
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|
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| Activity |
IC50 > 500000 nM
|
[1] | |||
| Compound Name |
Phosphinecarboxylic acid, dimethoxy-, cyclohexyl ester, oxide
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|
Investigative | Compound Info | ||
| Synonyms |
cyclohexyl dimethoxyphosphorylformate; CHEMBL91262; Dimethyl cyclohexoxycarbonylphosphonate; cyclohexyl dimethoxyphosphinecarboxylate oxide; SCHEMBL10890356; DTXSID30222637; BDBM50027542
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|
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| Activity |
IC50 > 500000 nM
|
[1] | |||
| Compound Name |
4-(Ethoxycarbonyl)phenyl diethoxyphosphinecarboxylate oxide
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|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL330012; SCHEMBL10892183; BDBM50027558; ZINC26649969; ethyl 4-diethoxyphosphorylcarbonyloxybenzoate; Diethyl 4-(ethoxycarbonyl)phenoxycarbonylphosphonate
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|
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| Activity |
IC50 > 500000 nM
|
[1] | |||
| Compound Name |
Disodium;ethyl 4-phosphonatocarbonyloxybenzoate
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|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL90135; SCHEMBL10936887
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|
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| Activity |
IC50 > 500000 nM
|
[1] | |||
| Compound Name |
Methoxy(sodiooxy)phosphinylformic acid phenyl ester
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|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL414219; sodium methyl phenoxycarbonylphosphonate
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|
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| Activity |
IC50 > 500000 nM
|
[1] | |||
| Compound Name |
Phosphinecarboxylic acid, bis(1-methylethoxy)-, methyl ester, oxide
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|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL91500; methyl diisopropoxyphosphinecarboxylate oxide; C8H17O5P; methyl di(propan-2-yloxy)phosphorylformate; DTXSID90208371; methyl diisopropoxyphosphorylformate; BDBM50027577; diisopropyl (methoxycarbonyl)phosphonate; methyl [bis(propan-2-yloxy)phosphoryl]formate; Methoxycarbonylphosphonic acid diisopropyl ester
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|
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| Activity |
IC50 > 500000 nM
|
[1] | |||
| Compound Name |
Phosphinecarboxylic acid, diethoxy-, 4-methoxyphenyl ester, oxide
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|
Investigative | Compound Info | ||
| Synonyms |
(4-methoxyphenyl) diethoxyphosphorylformate; CHEMBL314377; diethyl 4-methoxyphenoxycarbonylphosphonate; 4-methoxyphenyl diethoxyphosphinecarboxylate oxide; SCHEMBL10886984; DTXSID40222648; BDBM50027576
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|
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| Activity |
IC50 > 500000 nM
|
[1] | |||
| Compound Name |
Methyl [(4-acetylphenoxy)-methoxyphosphoryl]formate
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|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL327238; Phosphinecarboxylic acid, (4-acetylphenoxy)methoxy-, methyl ester, oxide; methyl (4-acetylphenoxy)(methoxy)phosphinecarboxylate oxide; SCHEMBL10889878; DTXSID30993092; BDBM50027551; Methyl p-acetylphenyl methoxycarbonylphosphonate; methyl [(4-acetylphenoxy)-methoxy-phosphoryl]formate; Methyl (4-acetylphenoxy)(methoxy)oxo-lambda~5~-phosphanecarboxylate
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|
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| Activity |
IC50 > 500000 nM
|
[1] | |||
| Compound Name |
Disodium;[1-adamantyloxy(oxido)phosphoryl]formate
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|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL89434
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|
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| Activity |
IC50 > 500000 nM
|
[1] | |||
| Compound Name |
(3,4-Dichlorophenyl) dimethoxyphosphorylformate
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|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL90586; hosphinecarboxylic acid, dimethoxy-, 3,4-dichlorophenyl ester, oxide; dimethyl 3,4-dichlorophenoxycarbonylphosphonate; 3,4-dichlorophenyl dimethoxyphosphinecarboxylate oxide; SCHEMBL10936917; DTXSID00222629; BDBM50027548
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|
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| Activity |
IC50 > 500000 nM
|
[1] | |||
| Compound Name |
Phosphinecarboxylic acid, dimethoxy-, cyclopentylmethyl ester, oxide
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|
Investigative | Compound Info | ||
| Synonyms |
cyclopentylmethyl dimethoxyphosphorylformate; CHEMBL91202; cyclopentylmethyl dimethoxyphosphinecarboxylate oxide; SCHEMBL11223539; DTXSID90222638; BDBM50027543
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|
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| Activity |
IC50 > 500000 nM
|
[1] | |||
| Compound Name |
4-(Ethoxycarbonyl)phenyl dimethoxyphosphinecarboxylate oxide
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|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL329550; BDBM50027579; ethyl 4-dimethoxyphosphorylcarbonyloxybenzoate; Dimethyl 4-(ethoxycarbonyl)phenoxycarbonylphosphonate
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|
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| Activity |
IC50 > 500000 nM
|
[1] | |||
| Compound Name |
Disodium (ethoxycarbonyl)phosphonate
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|
Investigative | Compound Info | ||
| Synonyms |
UNII-0YFB1C22IN; 0YFB1C22IN; CHEMBL92306; Disodium ethoxycarbonylphosphonate; Phosphinecarboxylic acid, dihydroxy-, ethyl ester, oxide, disodium salt; SCHEMBL10886559; DTXSID70993096; (Ethoxycarbonyl)phosphonic acid disodium salt; Q27237349
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|
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| Activity |
IC50 > 500000 nM
|
[1] | |||
| Compound Name |
Phosphinecarboxylic acid, dimethoxy-, 4-nitrophenyl ester, oxide
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|
Investigative | Compound Info | ||
| Synonyms |
(4-nitrophenyl) dimethoxyphosphorylformate; CHEMBL314735; 4-nitrophenyl dimethoxyphosphinecarboxylate oxide; SCHEMBL7925778; DTXSID60232769; BDBM50027575
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|
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| Activity |
IC50 > 500000 nM
|
[1] | |||
| Compound Name |
Phosphinecarboxylic acid, diethoxy-, 4-chlorophenyl ester, oxide
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|
Investigative | Compound Info | ||
| Synonyms |
(4-chlorophenyl) diethoxyphosphorylformate; CHEMBL90364; Diethyl 4-chlorophenoxycarbonylphosphonate; 4-chlorophenyl diethoxyphosphinecarboxylate oxide; SCHEMBL10888267; DTXSID00222649; BDBM50027549
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|
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| Activity |
IC50 > 500000 nM
|
[1] | |||
| Compound Name |
Methyl [1-adamantyloxy(methoxy)phosphoryl]formate
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|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL90381; methyl (1-adamantyloxy)(methoxy)phosphinecarboxylate oxide; SCHEMBL10885915; DTXSID70993091; BDBM50027547; Phosphinecarboxylic acid, methoxy(tricyclo(3.3.1.1(3,7))dec-1-yloxy)-, methyl ester, oxide; Methyl [(adamantan-1-yl)oxy](methoxy)oxo-lambda~5~-phosphanecarboxylate; Phosphinecarboxylic acid, methoxy(tricyclo[3.3.1.1~3,7~]dec-1-yloxy)-, methyl ester, oxide
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|
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| Activity |
IC50 > 500000 nM
|
[1] | |||
| Compound Name |
Methyl [(4-acetylphenoxy)-ethoxyphosphoryl]formate
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|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL88552; Phosphinecarboxylic acid, (4-acetylphenoxy)ethoxy-, methyl ester, oxide; methyl (4-acetylphenoxy)(ethoxy)phosphinecarboxylate oxide; SCHEMBL10889182; DTXSID801003998; BDBM50027574; methyl [(4-acetylphenoxy)-ethoxy-phosphoryl]formate; Methyl (4-acetylphenoxy)(ethoxy)oxo-lambda~5~-phosphanecarboxylate
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|
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| Activity |
IC50 > 500000 nM
|
[1] | |||
| Compound Name |
Ethyl hydroxyphenoxyphosphinecarboxylate oxide sodium salt
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|
Investigative | Compound Info | ||
| Synonyms |
sodium phenyl ethoxycarbonylphosphonate; CHEMBL89780; VIS 036; SCHEMBL10893393; Phosphinecarboxylic acid, hydroxyphenoxy-, ethyl ester, oxide, sodium salt
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| Activity |
IC50 > 500000 nM
|
[1] | |||
| Compound Name |
Phosphinecarboxylic acid, dimethoxy-, phenyl ester, oxide
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|
Investigative | Compound Info | ||
| Synonyms |
Phenyl dimethoxyphosphinecarboxylate oxide; phenyl dimethoxyphosphorylformate; CHEMBL91546; VIS 416; Dimethyl peonoxycarbonylphosphonate; dimethyl (phenoxycarbonyl)phosphonate; C9H11O5P; SCHEMBL4610736; DTXSID10222630; Dimethyl phenoxycarbonylphosphonate; BDBM50027555; Phenoxycarbonylphosphonic acid dimethyl ester
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| Activity |
IC50 > 500000 nM
|
[1] | |||
| Compound Name |
Disodium;(4-methylphenyl) phosphonatoformate
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|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL90196; SCHEMBL10935861
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|
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| Activity |
IC50 > 500000 nM
|
[1] | |||
| Compound Name |
Methyl [2,3-dihydro-1H-inden-5-yloxy(ethoxy)phosphoryl]formate
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|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL90370; Phosphinecarboxylic acid, ((2,3-dihydro-1H-inden-5-yl)oxy)ethoxy-, methyl ester, oxide; Phosphinecarboxylic acid, [(2,3-dihydro-1H-inden-5-yl)oxy]ethoxy-, methyl ester, oxide; SCHEMBL10894035; DTXSID10993090; BDBM50027567; methyl [ethoxy(indan-5-yloxy)phosphoryl]formate; methyl (2,3-dihydro-1H-inden-5-yloxy)(ethoxy)phosphinecarboxylate oxide; Methyl [(2,3-dihydro-1H-inden-5-yl)oxy](ethoxy)oxo-lambda~5~-phosphanecarboxylate
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|
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| Activity |
IC50 > 500000 nM
|
[1] | |||
| Compound Name |
Phosphinecarboxylic acid, bis(1-methylethoxy)-, 4-nitrophenyl ester, oxide
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|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL91487; 4-nitrophenyl diisopropoxyphosphinecarboxylate oxide; SCHEMBL569154; (4-nitrophenyl) di(propan-2-yloxy)phosphorylformate; DTXSID70232770; ZINC3653654; BDBM50027583; diisopropyl 4-nitrophenoxycarbonylphosphonate; (4-nitrophenyl) diisopropoxyphosphorylformate; 4-Nitrophenoxycarbonylphosphonic acid diisopropyl ester
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|
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| Activity |
IC50 > 500000 nM
|
[1] | |||
| Compound Name |
Disodium isopropoxycarbonylphosphonate
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|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL261980; SCHEMBL10887265
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|
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| Activity |
IC50 > 500000 nM
|
[1] | |||
| Compound Name |
Sodium ethyl (4-chlorophenoxy)carbonylphosphonate
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|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL91958
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|
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| Activity |
IC50 = 500000 nM
|
[1] | |||
| Compound Name |
Ethyl sodium (ethoxycarbonyl)phosphonate
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|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL90534; sodium ethyl ethoxycarbonylphosphonate; UNII-WNR8979H5T; WNR8979H5T; SCHEMBL10890101; Q27292738; (Ethoxycarbonyl)phosphonic acid sodium ethyl ester salt
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|
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| Activity |
IC50 > 500000 nM
|
[1] | |||
| Compound Name |
Sodium methyl benzyloxycarbonylphosphonate
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|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL329654; sodium methyl (benzyloxy)carbonylphosphonate; SCHEMBL10891606
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|
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| Activity |
IC50 > 500000 nM
|
[1] | |||
| Compound Name |
Sodium;2,3-dihydro-1H-inden-5-yloxy(methoxycarbonyl)phosphinate
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|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL92372; SCHEMBL10888121
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|
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| Activity |
IC50 > 500000 nM
|
[1] | |||
| Compound Name |
Phosphinecarboxylic acid, dimethoxy-, 1-methylethyl ester, oxide
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|
Investigative | Compound Info | ||
| Synonyms |
Dimethyl i-propoxycarbonylphosphonate; CHEMBL91590; isopropyl dimethoxyphosphinecarboxylate oxide; propan-2-yl dimethoxyphosphorylformate; SCHEMBL10890656; DTXSID10222635; isopropyl dimethoxyphosphorylformate; BDBM50027546
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|
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| Activity |
IC50 > 500000 nM
|
[1] | |||
| Compound Name |
Benzyl dimethoxyphosphorylformate
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|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL91591; benzyl dimethoxyphosphinecarboxylate oxide; Phosphinecarboxylic acid, dimethoxy-, phenylmethyl ester, oxide; SCHEMBL10885606; CTK1C5597; DTXSID30955099; Dimethyl benzyloxycarbonylphosphonate; BDBM50027532; dimethyl (benzyloxycarbonyl)phosphonate; Benzyl dimethoxy(oxo)-lambda~5~-phosphanecarboxylate
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|
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| Activity |
IC50 > 500000 nM
|
[1] | |||
| Compound Name |
Disodium;[(2,6-dimethylphenoxy)-oxidophosphoryl]formate
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL91954
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|
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| Activity |
IC50 > 500000 nM
|
[1] | |||
| Compound Name |
Phosphinecarboxylic acid, dimethoxy-, 4-methylphenyl ester, oxide
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|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL315606; Dimethyl p-tolyloxycarbonylphosphonate; 4-methylphenyl dimethoxyphosphinecarboxylate oxide; (4-methylphenyl) dimethoxyphosphorylformate; SCHEMBL10935165; p-tolyl dimethoxyphosphorylformate; DTXSID10222650; BDBM50027554
Click to Show/Hide
|
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| Activity |
IC50 > 500000 nM
|
[1] | |||
| Compound Name |
Disodium;(4-methoxyphenyl) phosphonatoformate
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|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL91569; SCHEMBL10933556
Click to Show/Hide
|
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| Activity |
IC50 > 500000 nM
|
[1] | |||
| Compound Name |
Methyl [(2,6-dimethylphenoxy)-ethoxyphosphoryl]formate
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|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL89984; Phosphinecarboxylic acid, (2,6-dimethylphenoxy)ethoxy-, methyl ester, oxide; methyl (2,6-dimethylphenoxy)(ethoxy)phosphinecarboxylate oxide; SCHEMBL10888512; DTXSID00993089; BDBM50027550; Ethyl, 2,6-dimethylphenyl methoxycarbonylphosphonate; methyl [(2,6-dimethylphenoxy)-ethoxy-phosphoryl]formate; Methyl (2,6-dimethylphenoxy)(ethoxy)oxo-lambda~5~-phosphanecarboxylate
Click to Show/Hide
|
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| Activity |
IC50 > 500000 nM
|
[1] | |||
| Compound Name |
Disodium (cyclohexyloxy)carbonylphosphonate
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|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL314538; SCHEMBL10889563
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|
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| Activity |
IC50 > 500000 nM
|
[1] | |||
| Compound Name |
Sodium butyl methoxycarbonylphosphonate
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL90095; SCHEMBL10893679
Click to Show/Hide
|
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| Activity |
IC50 > 500000 nM
|
[1] | |||
| Compound Name |
Disodium (cyclopentylmethoxy)carbonylphosphonate
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL91564; SCHEMBL11226111
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|
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| Activity |
IC50 > 500000 nM
|
[1] | |||
| Click to Show/Hide the Information of All Non Binders | |||||
| References | Top | ||||
|---|---|---|---|---|---|
| REF 1 | Synthesis of esters of phosphonoformic acid and their antiherpes activity. J Med Chem. 1983 Feb;26(2):264-70. | ||||
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