TTD_Target_ID Target_Name TTD_Drug_ID Drug_Name Drug_Highest_Status Drug_PubchemID Molecular_Formula Molecular_Weight Canonical_SMILES Activity Binder_Type T89846 Herpesvirus DNA polymerase B1FI8O Disodium (ethoxyoxydophosphanyl)formate Investigative 13077914 C3H5Na2O5P 198.02 CCOP(=O)(C(=O)[O-])[O-].[Na+].[Na+] IC50 > 500000 nM Non binder T89846 Herpesvirus DNA polymerase B1IS7A Sodium 2,6-dimethylphenyl methoxycarbonylphosphonate Investigative 23679409 C10H12NaO5P 266.16 CC1=C(C(=CC=C1)C)OP(=O)(C(=O)OC)[O-].[Na+] IC50 > 500000 nM Non binder T89846 Herpesvirus DNA polymerase B1J6DU Disodium phenoxycarbonylphosphonate Investigative 13077927 C7H5Na2O5P 246.06 C1=CC=C(C=C1)OC(=O)P(=O)([O-])[O-].[Na+].[Na+] IC50 > 500000 nM Non binder T89846 Herpesvirus DNA polymerase B21NYD Disodium butoxycarbonylphosphonate Investigative 13077922 C5H9Na2O5P 226.08 CCCCOC(=O)P(=O)([O-])[O-].[Na+].[Na+] IC50 > 500000 nM Non binder T89846 Herpesvirus DNA polymerase B2RWS3 Phosphinecarboxylic acid, hydroxymethoxy-, oxide, disodium salt Investigative 73183 C2H3Na2O5P 184 COP(=O)(C(=O)[O-])[O-].[Na+].[Na+] IC50 > 500000 nM Non binder T89846 Herpesvirus DNA polymerase B30CNO Disodium (benzyloxy)carbonylphosphonate Investigative 13077924 C8H7Na2O5P 260.089 C1=CC=C(C=C1)COC(=O)P(=O)([O-])[O-].[Na+].[Na+] IC50 > 500000 nM Non binder T89846 Herpesvirus DNA polymerase B36UWQ Phosphinecarboxylic acid, dibutoxy-, methyl ester, oxide Investigative 512112 C10H21O5P 252.24 CCCCOP(=O)(C(=O)OC)OCCCC IC50 > 500000 nM Non binder T89846 Herpesvirus DNA polymerase B37PCB Phosphinecarboxylic acid, dimethoxy-, butyl ester, oxide Investigative 512108 C7H15O5P 210.16 CCCCOC(=O)P(=O)(OC)OC IC50 > 500000 nM Non binder T89846 Herpesvirus DNA polymerase B3XW1Q Phosphinecarboxylic acid, dimethoxy-, cyclohexyl ester, oxide Investigative 512109 C9H17O5P 236.2 COP(=O)(C(=O)OC1CCCCC1)OC IC50 > 500000 nM Non binder T89846 Herpesvirus DNA polymerase B5S3KC 4-(Ethoxycarbonyl)phenyl diethoxyphosphinecarboxylate oxide Investigative 13077902 C14H19O7P 330.27 CCOC(=O)C1=CC=C(C=C1)OC(=O)P(=O)(OCC)OCC IC50 > 500000 nM Non binder T89846 Herpesvirus DNA polymerase B61VFC Disodium;ethyl 4-phosphonatocarbonyloxybenzoate Investigative 13077932 C10H9Na2O7P 318.13 CCOC(=O)C1=CC=C(C=C1)OC(=O)P(=O)([O-])[O-].[Na+].[Na+] IC50 > 500000 nM Non binder T89846 Herpesvirus DNA polymerase B69JMX Methoxy(sodiooxy)phosphinylformic acid phenyl ester Investigative 23679412 C8H8NaO5P 238.11 COP(=O)(C(=O)OC1=CC=CC=C1)[O-].[Na+] IC50 > 500000 nM Non binder T89846 Herpesvirus DNA polymerase B6LOM5 Phosphinecarboxylic acid, bis(1-methylethoxy)-, methyl ester, oxide Investigative 512111 C8H17O5P 224.19 CC(C)OP(=O)(C(=O)OC)OC(C)C IC50 > 500000 nM Non binder T89846 Herpesvirus DNA polymerase B6NEG8 Phosphinecarboxylic acid, diethoxy-, 4-methoxyphenyl ester, oxide Investigative 512114 C12H17O6P 288.23 CCOP(=O)(C(=O)OC1=CC=C(C=C1)OC)OCC IC50 > 500000 nM Non binder T89846 Herpesvirus DNA polymerase B6ZB0Y Methyl [(4-acetylphenoxy)-methoxyphosphoryl]formate Investigative 512125 C11H13O6P 272.19 CC(=O)C1=CC=C(C=C1)OP(=O)(C(=O)OC)OC IC50 > 500000 nM Non binder T89846 Herpesvirus DNA polymerase B8EO6J Disodium;[1-adamantyloxy(oxido)phosphoryl]formate Investigative 13077915 C11H15Na2O5P 304.19 C1C2CC3CC1CC(C2)(C3)OP(=O)(C(=O)[O-])[O-].[Na+].[Na+] IC50 > 500000 nM Non binder T89846 Herpesvirus DNA polymerase B9BJY3 (3,4-Dichlorophenyl) dimethoxyphosphorylformate Investigative 512117 C9H9Cl2O5P 299.04 COP(=O)(C(=O)OC1=CC(=C(C=C1)Cl)Cl)OC IC50 > 500000 nM Non binder T89846 Herpesvirus DNA polymerase B9MNA6 Phosphinecarboxylic acid, dimethoxy-, cyclopentylmethyl ester, oxide Investigative 512110 C9H17O5P 236.2 COP(=O)(C(=O)OCC1CCCC1)OC IC50 > 500000 nM Non binder T89846 Herpesvirus DNA polymerase BAMG62 4-(Ethoxycarbonyl)phenyl dimethoxyphosphinecarboxylate oxide Investigative 13077901 C12H15O7P 302.22 CCOC(=O)C1=CC=C(C=C1)OC(=O)P(=O)(OC)OC IC50 > 500000 nM Non binder T89846 Herpesvirus DNA polymerase BBJ39U Disodium (ethoxycarbonyl)phosphonate Investigative 73185 C3H5Na2O5P 198.02 CCOC(=O)P(=O)([O-])[O-].[Na+].[Na+] IC50 > 500000 nM Non binder T89846 Herpesvirus DNA polymerase BCOJ46 Phosphinecarboxylic acid, dimethoxy-, 4-nitrophenyl ester, oxide Investigative 512121 C9H10NO7P 275.15 COP(=O)(C(=O)OC1=CC=C(C=C1)[N+](=O)[O-])OC IC50 > 500000 nM Non binder T89846 Herpesvirus DNA polymerase BFX0Z4 Phosphinecarboxylic acid, diethoxy-, 4-chlorophenyl ester, oxide Investigative 512115 C11H14ClO5P 292.65 CCOP(=O)(C(=O)OC1=CC=C(C=C1)Cl)OCC IC50 > 500000 nM Non binder T89846 Herpesvirus DNA polymerase BG2DO9 Methyl [1-adamantyloxy(methoxy)phosphoryl]formate Investigative 512113 C13H21O5P 288.28 COC(=O)P(=O)(OC)OC12CC3CC(C1)CC(C3)C2 IC50 > 500000 nM Non binder T89846 Herpesvirus DNA polymerase BI1C7H Methyl [(4-acetylphenoxy)-ethoxyphosphoryl]formate Investigative 512126 C12H15O6P 286.22 CCOP(=O)(C(=O)OC)OC1=CC=C(C=C1)C(=O)C IC50 > 500000 nM Non binder T89846 Herpesvirus DNA polymerase BIK7X1 Ethyl hydroxyphenoxyphosphinecarboxylate oxide sodium salt Investigative 23679408 C9H10NaO5P 252.14 CCOC(=O)P(=O)([O-])OC1=CC=CC=C1.[Na+] IC50 > 500000 nM Non binder T89846 Herpesvirus DNA polymerase BIX8R3 Phosphinecarboxylic acid, dimethoxy-, phenyl ester, oxide Investigative 512118 C9H11O5P 230.15 COP(=O)(C(=O)OC1=CC=CC=C1)OC IC50 > 500000 nM Non binder T89846 Herpesvirus DNA polymerase BJ94DI Disodium;(4-methylphenyl) phosphonatoformate Investigative 13077928 C8H7Na2O5P 260.089 CC1=CC=C(C=C1)OC(=O)P(=O)([O-])[O-].[Na+].[Na+] IC50 > 500000 nM Non binder T89846 Herpesvirus DNA polymerase BJNI91 Methyl [2,3-dihydro-1H-inden-5-yloxy(ethoxy)phosphoryl]formate Investigative 512124 C13H17O5P 284.24 CCOP(=O)(C(=O)OC)OC1=CC2=C(CCC2)C=C1 IC50 > 500000 nM Non binder T89846 Herpesvirus DNA polymerase BJX19C Phosphinecarboxylic acid, bis(1-methylethoxy)-, 4-nitrophenyl ester, oxide Investigative 512122 C13H18NO7P 331.26 CC(C)OP(=O)(C(=O)OC1=CC=C(C=C1)[N+](=O)[O-])OC(C)C IC50 > 500000 nM Non binder T89846 Herpesvirus DNA polymerase BKW4O8 Disodium isopropoxycarbonylphosphonate Investigative 13077921 C4H7Na2O5P 212.05 CC(C)OC(=O)P(=O)([O-])[O-].[Na+].[Na+] IC50 > 500000 nM Non binder T89846 Herpesvirus DNA polymerase BLI08Y Sodium ethyl (4-chlorophenoxy)carbonylphosphonate Investigative 23679413 C9H9ClNaO5P 286.58 CCOP(=O)(C(=O)OC1=CC=C(C=C1)Cl)[O-].[Na+] IC50 = 500000 nM Non binder T89846 Herpesvirus DNA polymerase BMF3N7 Ethyl sodium (ethoxycarbonyl)phosphonate Investigative 23679407 C5H10NaO5P 204.09 CCOC(=O)P(=O)([O-])OCC.[Na+] IC50 > 500000 nM Non binder T89846 Herpesvirus DNA polymerase BMW3D6 Sodium methyl benzyloxycarbonylphosphonate Investigative 23679405 C9H10NaO5P 252.14 COP(=O)(C(=O)OCC1=CC=CC=C1)[O-].[Na+] IC50 > 500000 nM Non binder T89846 Herpesvirus DNA polymerase BNE6K7 Sodium;2,3-dihydro-1H-inden-5-yloxy(methoxycarbonyl)phosphinate Investigative 23679410 C11H12NaO5P 278.17 COC(=O)P(=O)([O-])OC1=CC2=C(CCC2)C=C1.[Na+] IC50 > 500000 nM Non binder T89846 Herpesvirus DNA polymerase BP8EX0 Phosphinecarboxylic acid, dimethoxy-, 1-methylethyl ester, oxide Investigative 512107 C6H13O5P 196.14 CC(C)OC(=O)P(=O)(OC)OC IC50 > 500000 nM Non binder T89846 Herpesvirus DNA polymerase BR1MO0 Benzyl dimethoxyphosphorylformate Investigative 512106 C10H13O5P 244.18 COP(=O)(C(=O)OCC1=CC=CC=C1)OC IC50 > 500000 nM Non binder T89846 Herpesvirus DNA polymerase BT3AY5 Disodium;[(2,6-dimethylphenoxy)-oxidophosphoryl]formate Investigative 13077919 C9H9Na2O5P 274.12 CC1=C(C(=CC=C1)C)OP(=O)(C(=O)[O-])[O-].[Na+].[Na+] IC50 > 500000 nM Non binder T89846 Herpesvirus DNA polymerase BU0VS2 Phosphinecarboxylic acid, dimethoxy-, 4-methylphenyl ester, oxide Investigative 512116 C10H13O5P 244.18 CC1=CC=C(C=C1)OC(=O)P(=O)(OC)OC IC50 > 500000 nM Non binder T89846 Herpesvirus DNA polymerase BU8HK6 Disodium;(4-methoxyphenyl) phosphonatoformate Investigative 13077929 C8H7Na2O6P 276.09 COC1=CC=C(C=C1)OC(=O)P(=O)([O-])[O-].[Na+].[Na+] IC50 > 500000 nM Non binder T89846 Herpesvirus DNA polymerase BUJ1A0 Methyl [(2,6-dimethylphenoxy)-ethoxyphosphoryl]formate Investigative 512123 C12H17O5P 272.23 CCOP(=O)(C(=O)OC)OC1=C(C=CC=C1C)C IC50 > 500000 nM Non binder T89846 Herpesvirus DNA polymerase BYS1E4 Disodium (cyclohexyloxy)carbonylphosphonate Investigative 13077925 C7H11Na2O5P 252.11 C1CCC(CC1)OC(=O)P(=O)([O-])[O-].[Na+].[Na+] IC50 > 500000 nM Non binder T89846 Herpesvirus DNA polymerase BYUX62 Disodium;(4-chlorophenyl) phosphonatoformate Investigative 13077930 C7H4ClNa2O5P 280.51 C1=CC(=CC=C1OC(=O)P(=O)([O-])[O-])Cl.[Na+].[Na+] IC50 = 250000 nM Non binder T89846 Herpesvirus DNA polymerase BZ7O2W Sodium butyl methoxycarbonylphosphonate Investigative 23679406 C6H12NaO5P 218.12 CCCCOP(=O)(C(=O)OC)[O-].[Na+] IC50 > 500000 nM Non binder T89846 Herpesvirus DNA polymerase BZ9KQ1 Disodium (cyclopentylmethoxy)carbonylphosphonate Investigative 13077926 C7H11Na2O5P 252.11 C1CCC(C1)COC(=O)P(=O)([O-])[O-].[Na+].[Na+] IC50 > 500000 nM Non binder