Target Poor or Non Binder(s) Information
| Target General Information | Top | ||||
|---|---|---|---|---|---|
| Target ID | T89466 | Target Info | |||
| Target Name | Thioredoxin glutathione reductase (TGR) | ||||
| Synonyms |
Thioredoxin reductase TR2; Thioredoxin reductase 3; Thioredoxin and glutathione reductase; TGR
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| Target Type | Literature-reported Target | ||||
| Gene Name | TXNRD3 | ||||
| Biochemical Class | Sulfur donor oxidoreductase | ||||
| UniProt ID | |||||
| Poor Binders of This Target (in total, 34 binders) | Download | Top | |||
|---|---|---|---|---|---|
| Compound Name |
4-nitrobenzo[c][1,2,5]thiadiazole
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Investigative | Compound Info | ||
| Synonyms |
4-Nitro-2,1,3-benzothiadiazole; 6583-06-8; 4-nitrobenzo[c][1,2,5]thiadiazole; 4-Nitropiazthiole; 2,1,3-Benzothiadiazole, 4-nitro-; NSC404747; CHEMBL383084; 4-Nitro-1,2,3-benzothiadiazole; 4-Nitro-benzo[1,2,5]thiadiazole; 4-nitrobenzo[c]1,2,5-thiadiazole; ACMC-1B59L; Oprea1_370043; 4-Bromo-2,8-dimethylphenol; C6H3N3O2S; 4-Nitro-2,3-benzothiadiazole; SCHEMBL2213406; AC1Q202C; AC1L30J9; CTK5C3163; DTXSID10216019; 4-nitrobenzo-2,1,3-thiadiazole; MolPort-004-288-376; IWQKAMJGVIHECB-UHFFFAOYSA-N; MolPort-001-779-862
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| Activity |
IC50 = 50000 nM
|
[1] | |||
| Compound Name |
ELLAGIC ACID
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Investigative | Compound Info | ||
| Synonyms |
ellagic acid; 476-66-4; Benzoaric acid; Lagistase; Eleagic acid; Alizarine Yellow; Elagostasine; 2,3,7,8-Tetrahydroxychromeno[5,4,3-cde]chromene-5,10-dione; Ellagic acid dihydrate; Llagic acid; Acide ellagique; Acido elagico; Acidum ellagicum; C.I. 55005; Gallogen (VAN); Gallogen (astringent); C.I. 75270; Ellagate; Ellagic acid [INN:DCF]; UNII-19YRN3ZS9P; Acido elagico [INN-Spanish]; CCRIS 774; Gallogen, astringent; Acide ellagique [INN-French]; Acidum ellagicum [INN-Latin]; MLS000069632; C14H6O8; EINECS 207-508-3; NSC407286; NSC 40728
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| Activity |
IC50 = 78300 nM
|
[2] | |||
| Compound Name |
8'-[(4-Bromophenyl)methoxy]spiro[2,4-dioxatricyclo[7.3.1.05,13]trideca-1(12),5,7,9(13),10-pentaene-3,4'-naphthalene]-1'-one
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL86449; BDBM50218863; 5-(4-Bromobenzyloxy)spiro[naphthalene-1(4H),2'-naphtho[1,8-de]-1,3-dioxin]-4-one
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| Activity |
IC50 ~ 50000 nM
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[3] | |||
| Compound Name |
8'-[(E)-2-Methylbut-2-enoxy]spiro[2,4-dioxatricyclo[7.3.1.05,13]trideca-1(12),5,7,9(13),10-pentaene-3,4'-naphthalene]-1'-one
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL328520; BDBM50218865; 5-[[(E)-2-Methyl-2-butenyl]oxy]spiro[naphthalene-1(4H),2'-naphtho[1,8-de]-1,3-dioxin]-4-one
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| Activity |
IC50 ~ 50000 nM
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[3] | |||
| Compound Name |
8'-Prop-2-ynoxyspiro[2,4-dioxatricyclo[7.3.1.05,13]trideca-1(12),5,7,9(13),10-pentaene-3,4'-naphthalene]-1'-one
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL91726; BDBM50218810; 5-(Propargyloxy)spiro[naphthalene-1(4H),2'-naphtho[1,8-de]-1,3-dioxin]-4-one
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| Activity |
IC50 = 50000 nM
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[3] | |||
| Compound Name |
8'-Hexoxyspiro[2,4-dioxatricyclo[7.3.1.05,13]trideca-1(12),5,7,9(13),10-pentaene-3,4'-naphthalene]-1'-one
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL90439; BDBM50218799; 5-(Hexyloxy)spiro[naphthalene-1(4H),2'-naphtho[1,8-de]-1,3-dioxin]-4-one
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| Activity |
IC50 ~ 50000 nM
|
[3] | |||
| Compound Name |
8'-(2-Methylprop-2-enoxy)spiro[2,4-dioxatricyclo[7.3.1.05,13]trideca-1(12),5,7,9(13),10-pentaene-3,4'-naphthalene]-1'-one
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL419314; BDBM50218842; 5-(2-Methyl-2-propenyloxy)spiro[naphthalene-1(4H),2'-naphtho[1,8-de]-1,3-dioxin]-4-one
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| Activity |
IC50 ~ 50000 nM
|
[3] | |||
| Compound Name |
8'-[(4-Methoxyphenyl)methoxy]spiro[2,4-dioxatricyclo[7.3.1.05,13]trideca-1(12),5,7,9(13),10-pentaene-3,4'-naphthalene]-1'-one
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL91727; BDBM50218856; 5-(4-Methoxybenzyloxy)spiro[naphthalene-1(4H),2'-naphtho[1,8-de]-1,3-dioxin]-4-one
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| Activity |
IC50 ~ 50000 nM
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[3] | |||
| Compound Name |
8'-(Pyridin-2-ylmethoxy)spiro[2,4-dioxatricyclo[7.3.1.05,13]trideca-1(12),5,7,9(13),10-pentaene-3,4'-naphthalene]-1'-one
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Investigative | Compound Info | ||
| Synonyms |
SR-11; CHEMBL329397; BDBM50218809; 5-(2-Pyridinylmethoxy)spiro[naphthalene-1(4H),2'-naphtho[1,8-de]-1,3-dioxin]-4-one
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| Activity |
IC50 ~ 50000 nM
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[3] | |||
| Compound Name |
8'-[(E)-3-Phenylprop-2-enoxy]spiro[2,4-dioxatricyclo[7.3.1.05,13]trideca-1(12),5,7,9(13),10-pentaene-3,4'-naphthalene]-1'-one
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL89726; BDBM50218808; 5-(trans-Cinnamyloxy)spiro[naphthalene-1(4H),2'-naphtho[1,8-de]-1,3-dioxin]-4-one
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| Activity |
IC50 ~ 50000 nM
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[3] | |||
| Compound Name |
8'-[[5-(2-Chlorophenyl)furan-2-yl]methoxy]spiro[2,4-dioxatricyclo[7.3.1.05,13]trideca-1(12),5,7,9(13),10-pentaene-3,4'-naphthalene]-1'-one
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL89586; BDBM50218805
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| Activity |
IC50 ~ 50000 nM
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[3] | |||
| Compound Name |
8'-(2-Phenylethoxy)spiro[2,4-dioxatricyclo[7.3.1.05,13]trideca-1(12),5,7,9(13),10-pentaene-3,4'-naphthalene]-1'-one
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL89211; BDBM50218811; 5-(Phenethyloxy)spiro[naphthalene-1(4H),2'-naphtho[1,8-de]-1,3-dioxin]-4-one
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| Activity |
IC50 ~ 50000 nM
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[3] | |||
| Compound Name |
8'-[(3-Methoxyphenyl)methoxy]spiro[2,4-dioxatricyclo[7.3.1.05,13]trideca-1(12),5,7,9(13),10-pentaene-3,4'-naphthalene]-1'-one
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL88947; BDBM50218864; 5-(3-Methoxybenzyloxy)spiro[naphthalene-1(4H),2'-naphtho[1,8-de]-1,3-dioxin]-4-one
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| Activity |
IC50 ~ 50000 nM
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[3] | |||
| Compound Name |
8'-[[5-(3-Chlorophenyl)furan-2-yl]methoxy]spiro[2,4-dioxatricyclo[7.3.1.05,13]trideca-1(12),5,7,9(13),10-pentaene-3,4'-naphthalene]-1'-one
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL329895; BDBM50218846
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| Activity |
IC50 ~ 50000 nM
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[3] | |||
| Compound Name |
8'-(Furan-3-ylmethoxy)spiro[2,4-dioxatricyclo[7.3.1.05,13]trideca-1(12),5,7,9(13),10-pentaene-3,4'-naphthalene]-1'-one
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Investigative | Compound Info | ||
| Synonyms |
SR-10; CHEMBL89858; BDBM50218853; 5-(3-Furanylmethoxy)spiro[naphthalene-1(4H),2'-naphtho[1,8-de]-1,3-dioxin]-4-one
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| Activity |
IC50 ~ 50000 nM
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[3] | |||
| Compound Name |
(1'R,3'R,5'S,7'R)-Spiro[2,4-dioxatricyclo[7.3.1.05,13]trideca-1(12),5,7,9(13),10-pentaene-3,6'-4,12-dioxatetracyclo[5.4.1.01,7.03,5]dodecane]-2',8'-dione
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL439585; BDBM50218860
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| Activity |
IC50 ~ 50000 nM
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[3] | |||
| Compound Name |
8'-[(4-Chlorophenyl)methoxy]spiro[2,4-dioxatricyclo[7.3.1.05,13]trideca-1(12),5,7,9(13),10-pentaene-3,4'-naphthalene]-1'-one
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL316338; BDBM50218803; 5-(4-Chlorobenzyloxy)spiro[naphthalene-1(4H),2'-naphtho[1,8-de]-1,3-dioxin]-4-one
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| Activity |
IC50 ~ 50000 nM
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[3] | |||
| Compound Name |
8'-[[5-[3-(Trifluoromethyl)phenyl]furan-2-yl]methoxy]spiro[2,4-dioxatricyclo[7.3.1.05,13]trideca-1(12),5,7,9(13),10-pentaene-3,4'-naphthalene]-1'-one
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL312843; BDBM50218850
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| Activity |
IC50 ~ 50000 nM
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[3] | |||
| Compound Name |
8'-[(Z)-2-Methylbut-2-enoxy]spiro[2,4-dioxatricyclo[7.3.1.05,13]trideca-1(12),5,7,9(13),10-pentaene-3,4'-naphthalene]-1'-one
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL91650; BDBM50218806; 5-[[(Z)-2-Methyl-2-butenyl]oxy]spiro[naphthalene-1(4H),2'-naphtho[1,8-de]-1,3-dioxin]-4-one
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| Activity |
IC50 ~ 50000 nM
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[3] | |||
| Compound Name |
8'-(Pyridin-4-ylmethoxy)spiro[2,4-dioxatricyclo[7.3.1.05,13]trideca-1(12),5,7,9(13),10-pentaene-3,4'-naphthalene]-1'-one
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL440697; SR-13; BDBM50218854; 5-(4-Pyridinylmethoxy)spiro[naphthalene-1(4H),2'-naphtho[1,8-de]-1,3-dioxin]-4-one
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| Activity |
IC50 ~ 50000 nM
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[3] | |||
| Compound Name |
8'-(Furan-2-ylmethoxy)spiro[2,4-dioxatricyclo[7.3.1.05,13]trideca-1(12),5,7,9(13),10-pentaene-3,4'-naphthalene]-1'-one
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL423684; SR-7; BDBM50218852
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| Activity |
IC50 ~ 50000 nM
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[3] | |||
| Compound Name |
8'-[(E)-Hex-3-enoxy]spiro[2,4-dioxatricyclo[7.3.1.05,13]trideca-1(12),5,7,9(13),10-pentaene-3,4'-naphthalene]-1'-one
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL88438; BDBM50218807; 5-[[(E)-3-Hexenyl]oxy]spiro[naphthalene-1(4H),2'-naphtho[1,8-de]-1,3-dioxin]-4-one
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| Activity |
IC50 ~ 50000 nM
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[3] | |||
| Compound Name |
8'-(Pyridin-3-ylmethoxy)spiro[2,4-dioxatricyclo[7.3.1.05,13]trideca-1(12),5,7,9(13),10-pentaene-3,4'-naphthalene]-1'-one
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Investigative | Compound Info | ||
| Synonyms |
SR-12; CHEMBL86881; BDBM50218845; 5-(3-Pyridinylmethoxy)spiro[naphthalene-1(4H),2'-naphtho[1,8-de]-1,3-dioxin]-4-one
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| Activity |
IC50 ~ 50000 nM
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[3] | |||
| Compound Name |
8'-Prop-2-enoxyspiro[2,4-dioxatricyclo[7.3.1.05,13]trideca-1(12),5,7,9(13),10-pentaene-3,4'-naphthalene]-1'-one
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL88268; SR-14; BDBM50218851; 5-(Allyloxy)spiro[naphthalene-1(4H),2'-naphtho[1,8-de]-1,3-dioxin]-4-one
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| Activity |
IC50 ~ 50000 nM
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[3] | |||
| Compound Name |
8'-(3-Methylbut-2-enoxy)spiro[2,4-dioxatricyclo[7.3.1.05,13]trideca-1(12),5,7,9(13),10-pentaene-3,4'-naphthalene]-1'-one
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL89080; BDBM50218855; 5-(Isopentenyloxy)spiro[naphthalene-1(4H),2'-naphtho[1,8-de]-1,3-dioxin]-4-one
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| Activity |
IC50 ~ 50000 nM
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[3] | |||
| Compound Name |
5-Methoxyspiro[naphthalene-1(4H),2'-[1,3]dioxane]-4-one
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL313317; BDBM50218844
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| Activity |
IC50 = 50000 nM
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[3] | |||
| Compound Name |
8'-[(E)-But-2-enoxy]spiro[2,4-dioxatricyclo[7.3.1.05,13]trideca-1(12),5,7,9(13),10-pentaene-3,4'-naphthalene]-1'-one
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL421545; BDBM50218866
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| Activity |
IC50 ~ 50000 nM
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[3] | |||
| Compound Name |
8'-[[5-[2-(Trifluoromethyl)phenyl]furan-2-yl]methoxy]spiro[2,4-dioxatricyclo[7.3.1.05,13]trideca-1(12),5,7,9(13),10-pentaene-3,4'-naphthalene]-1'-one
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL88831; BDBM50218813
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| Activity |
IC50 ~ 50000 nM
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[3] | |||
| Compound Name |
Flavellagic acid
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Investigative | Compound Info | ||
| Synonyms |
UNII-YZX6YN0KUZ; YZX6YN0KUZ; CHEMBL1688543; NSC335996; (1)Benzopyrano(5,4,3-cde)(1)benzopyran-5,10-dione, 1,2,3,7,8-pentahydroxy-; [1]Benzopyrano[5,4,3-cde][1]benzopyran-5,10-dione, 1,2,3,7,8-pentahydroxy-; pentahydroxy[?]dione; NSC 335996; DTXSID60225010; ZINC5784243; BDBM50339128; NSC-335996; NCI60_002950
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| Activity |
IC50 = 51700 nM
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[2] | |||
| Compound Name |
4,5-Dinitro-1,3-benzodioxole
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL206829; 4,5-dinitrobenzo[d][1,3]dioxole; C7H4N2O6; Dinitro-methylendioxybenzole; ZINC4837050; BDBM50182121; STL325677; AKOS022141662; MCULE-8386142802
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| Activity |
IC50 = 80000 nM
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[1] | |||
| Compound Name |
5-Nitro-2,1,3-benzothiadiazole
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Investigative | Compound Info | ||
| Synonyms |
5-nitrobenzo-2,1,3-thiadiazole; 5-nitrobenzo[c][1,2,5]thiadiazole; NSC169218; 5-(Hydroxy(oxido)amino)-2,1,3-benzothiadiazole; CHEMBL206713; NSC 169218; Maybridge1_005863; Oprea1_705286; SCHEMBL922633; CTK4D1247; HMS558C11; ZINC71460; DTXSID60167385; 2,1,3-Benzothiadiazole,5-nitro-; 5-nitrobenzo[c]1,2,5-thiadiazole; KS-00001A6F; BDBM50182129; MFCD00114840; RDP 00064; AKOS003197175; MCULE-9376436434; NSC-169218; AM806177; AS-61005; EU-0066875; ST50976376; SR-01000389716; SR-01000389716-1
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| Activity |
IC50 = 90000 nM
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[1] | |||
| Compound Name |
4-Chloro-3,5-dinitrobenzotrifluoride
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Investigative | Compound Info | ||
| Synonyms |
2-Chloro-1,3-dinitro-5-(trifluoromethyl)benzene; 3,5-Dinitro-4-chlorobenzotrifluoride; Benzene, 2-chloro-1,3-dinitro-5-(trifluoromethyl)-; 1,3-dinitro-2-chloro-5-trifluoromethylbenzene; 1-Chloro-2,6-dinitro-4-(trifluoromethyl)benzene; CHLORALIN; 2,6-Dinitro-4-trifluoromethylchlorobenzene; Trifluoromethyl-3,5-dinitro-4-chlorobenzene; 4-Chloro-3,5-dinitro-a,a,a-trifluorotoluene; UNII-T97IUB50MN; 4-(Trifluoromethyl)-2,6-dinitrochlorobenzene; NSC 88274; Benzotrifluoride, 4-chloro-3,5-dinitro-; DNT-Cl; Benzene, 2-chloro-5-(trifluoromethyl)-1,3-dinitro-; 4-Chloro-alpha,alpha,alpha-trifluoro-3,5-dinitrotoluene; MFCD00007068; T97IUB50MN; 4-Chloro-3,5-dinitro-alpha,alpha,alpha-trifluorotoluene; CHEMBL144530; 2-Chloro-1,3-dinitro-5-trifluoromethyl-benzene; 2-chloro-5-(trifluoromethyl)-1,3-dinitrobenzene; CCRIS 2818; HSDB 4262; EINECS 206-889-3; BRN 1220937; PubChem2188; 3,5-Dinitro-4-chloro-alpha,alpha,alpha-trifluorotoluene; Toluene, 4-chloro-alpha,alpha,alpha-trifluoro-3,5-dinitro-; DSSTox_CID_4781; ACMC-209sg0; EC 206-889-3; DSSTox_RID_77529; NCIOpen2_005439; DSSTox_GSID_24781; KSC496E0D; SCHEMBL455937; DTXSID8024781; CTK3J6201; KS-00000WKZ; Toluene, 4-chloro-3,5-dinitro-alpha,alpha,alpha-trifluoro-; EBD49790; NSC88274; ZINC2022399; Tox21_200966; ANW-41134; BBL027633; BDBM50068343; NSC-88274; SBB056879; STL371257; 4-chloro-3,5-dinitrotrifluorotoluene; 3,5-dinitro-4-chlorobenzotrifluoride;; 4-chloro-3,5-dinitro benzotrifluoride; 4-chloro-3,5-dinitro-benzotrifluoride; AKOS000120597; 4-Chloro-3, 5-dinitrobenzotrifluoride; LS10483; MCULE-7040151531; PF10239; Benzene,3-dinitro-5-(trifluoromethyl)-; NCGC00091329-01; NCGC00091329-02; NCGC00091329-03; NCGC00258519-01; AC-10850; 4-Chloro-3,5-dinitrobenzotrifluoride, 98%; FT-0601466; ST50308329; 4-Chloro-3,.alpha.,.alpha.-trifluorotoluene; 1-trifluoromethyl-3,5-dinitro-4-chlorobenzene; 2,6-dinitro-4-trifluoromethyl-1-chlorobenzene; 2-chloro-1,3-dinitro-5-trifluoromethylbenzene; 2-chloro-5-trifluoromethyl-1,3-dinitrobenzene; Y-8707; Toluene,.alpha.,.alpha.-trifluoro-3,5-dinitro-; 2-CHLORO-1,3-5-(TRIFLUOROMETHYL)BENZENE; Benzene, 1-chloro-2,6-dinitro-4-trifluoromethyl; W-106439; 4-CHLORO-3,5-DINITRO-1-TRIFLUOROMETHYLBENZENE; Q15632822; 4-Chloro-.alpha.,.alpha.-trifluoro-3,5-dinitrotoluene; 3,5-Dinitro-4-chloro-.alpha.,.alpha.,.alpha.-trifluorotoluene; 4-Chloro-.alpha.,.alpha.,.alpha.-trifluoro-3,5-dinitrotoluene; 4-Chloro-3,5-dinitro-.alpha.,.alpha.,.alpha.-trifluorotoluene; Toluene, 4-chloro-.alpha.,.alpha.,.alpha.-trifluoro-3,5-dinitro-; Toluene, 4-chloro-3,5-dinitro-.alpha.,.alpha.,.alpha.-trifluoro-
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| Activity |
IC50 = 100000 nM
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[1] | |||
| Compound Name |
6,7-Dinitroquinoxaline
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL380953; Quinoxaline, 6,7-dinitro-; SCHEMBL1351219; CTK2F6883; DTXSID80369187; ZINC5280674; BDBM50182124; AKOS024306934; MCULE-7631939426; ST50307337
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| Activity |
IC50 = 140000 nM
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[1] | |||
| Compound Name |
Bis(2-nitro-4-(trifluoromethyl)phenyl)sulfane
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL204687; NSC39135; CTK4H6837; DTXSID10284814; ZINC1671152; BDBM50182125; NSC-39135; STK213636; AKOS003671425; MCULE-9314199041; 1,1'-sulfanediylbis[2-nitro-4-(trifluoromethyl)benzene]; Benzene,1,1'-thiobis[2-nitro-4-(trifluoromethyl)- (9CI)
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| Activity |
IC50 ~ 150000 nM
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[1] | |||
| Click to Show/Hide the Information of All Poor Binders | |||||
| Non Binders of This Target (in total, 3 non binders) | Download | Top | |||
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| Compound Name |
6-Nitroquinoxaline
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Investigative | Compound Info | ||
| Synonyms |
Quinoxaline, 6-nitro-; 6-nitro-quinoxaline; TCMDC-123943; CHEMBL380630; MFCD00462822; NSC48950; NSC 48950; Quinoxaline,6-nitro-; PubChem18738; 6-Nitroquinoxaline, 97%; SCHEMBL212004; WLN: T66 BN ENJ HNW; DTXSID70216616; ZINC167696; ACT10850; ALBB-013496; BCP20131; KS-00000E3Z; ANW-75036; BDBM50182127; NSC-48950; SBB009870; STK735878; AKOS001740024; MCULE-2817039419; AC-30702; ST060176; SY007246; AB0041934; DB-024455; CS-0035479; FT-0680085; Y9767; Q-9027; 12P-625; J-518966
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| Activity |
IC50 > 200000 nM
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[1] | |||
| Compound Name |
5-Nitro-1,3-benzodioxole
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Investigative | Compound Info | ||
| Synonyms |
5-nitrobenzo[d][1,3]dioxole; 1,2-(Methylenedioxy)-4-nitrobenzene; 3,4-Methylenedioxynitrobenzene; 1,3-Benzodioxole, 5-nitro-; Methylenedioxynitrobenzene; 5-Nitrobenzodioxole; 1,2-methylenedioxy-4-nitrobenzene; 5-nitro-2H-1,3-benzodioxole; 3,4-(Methylenedioxy)-1-nitrobenzene; Benzene, 1,2-(methylenedioxy)-4-nitro-; CHEMBL379408; MFCD00005824; NSC5562; NSC 5562; EINECS 220-055-6; PubChem22908; ACMC-1CCUS; 5-Nitro-1,3-dioxaindan; 3,4methylenedioxynitrobenzene; 1,3-Benzodioxole,5-nitro-; SCHEMBL141303; 4,5-Methylenedioxynitrobenzene; DTXSID5062558; CTK4F7390; 1-nitro-3,4-methylenedioxybenzene; 4,5-methylenedioxy-1-nitrobenzene; ZINC566580; NSC-5562; 5-nitro-2H-benzo[d]1,3-dioxolene; ANW-25929; BDBM50023678; STK318151; Benzene,2-(methylenedioxy)-4-nitro-; AKOS002846253; AKOS015889598; MCULE-6737368383; PS-4024; VZ20380; DB-046888; 1,2-(Methylenedioxy)-4-nitrobenzene, 98%; CS-0059218; FT-0606468; M0848; ST45025429; K-6809; 620M442; W-107190; F0001-3419
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| Activity |
IC50 > 200000 nM
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[1] | |||
| Compound Name |
3,5-Dinitrobenzotrifluoride
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Investigative | Compound Info | ||
| Synonyms |
1,3-dinitro-5-(trifluoromethyl)benzene; Benzene, 1,3-dinitro-5-(trifluoromethyl)-; alpha,alpha,alpha-Trifluoro-3,5-dinitrotoluene; MFCD00007233; CHEMBL380842; EINECS 206-935-2; PubChem10396; AI3-28908; 3, 5-Dinitrotrifluorotoluene; 3,5-dinitro-benzotrifluoride; SCHEMBL1005841; CTK5I2440; KS-00000EMZ; DTXSID40193142; 3,5-Dinitrobenzotrifluoride, 99%; ZINC2166808; 3,5-?Dinitrobenzotrifluoride, 98%; BDBM50182126; SBB057254; AKOS001022943; 1,3-Dinitro-5-trifluoromethyl-benzene; AC-2899; AF10078; MCULE-9100843113; VZ25864; BR-47294; PS-10451; SC-04262; 3,5-DINITRO TRIFLUOROMETHYL BENZENE; 3,5-DINITRO-A,A,A-TRIFLUOROTOLUENE; AB0011778; AM20060919; D2699; FT-0614719; ST50046319; 1,3-DINITRO-5-(TRFLUOROMETHYL)BENZENE; 3,5-Dinitro-alpha,alpha,alpha-trifluorotoluene; C-4585; W-106379
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| Activity |
IC50 > 200000 nM
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[1] | |||
| References | Top | ||||
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| REF 1 | Specific inhibitors of Plasmodium falciparum thioredoxin reductase as potential antimalarial agents. Bioorg Med Chem Lett. 2006 Apr 15;16(8):2283-92. | ||||
| REF 2 | Compounds structurally related to ellagic acid show improved antiplasmodial activity. Antimicrob Agents Chemother. 2009 Feb;53(2):622-30. | ||||
| REF 3 | New inhibitors of the thioredoxin-thioredoxin reductase system based on a naphthoquinone spiroketal natural product lead. Bioorg Med Chem Lett. 2001 Oct 8;11(19):2637-41. | ||||
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