Drug Information
Drug General Information | Top | |||
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Drug ID |
D0V8FG
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Former ID |
DNC006447
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Drug Name |
4-nitrobenzo[c][1,2,5]thiadiazole
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Synonyms |
4-Nitro-2,1,3-benzothiadiazole; 6583-06-8; 4-nitrobenzo[c][1,2,5]thiadiazole; 4-Nitropiazthiole; 2,1,3-Benzothiadiazole, 4-nitro-; NSC404747; CHEMBL383084; 4-Nitro-1,2,3-benzothiadiazole; 4-Nitro-benzo[1,2,5]thiadiazole; 4-nitrobenzo[c]1,2,5-thiadiazole; ACMC-1B59L; Oprea1_370043; 4-Bromo-2,8-dimethylphenol; C6H3N3O2S; 4-Nitro-2,3-benzothiadiazole; SCHEMBL2213406; AC1Q202C; AC1L30J9; CTK5C3163; DTXSID10216019; 4-nitrobenzo-2,1,3-thiadiazole; MolPort-004-288-376; IWQKAMJGVIHECB-UHFFFAOYSA-N; MolPort-001-779-862
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Drug Type |
Small molecular drug
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Indication | Discovery agent [ICD-11: N.A.] | Investigative | [1] | |
Structure |
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Download2D MOL |
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Formula |
C6H3N3O2S
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Canonical SMILES |
C1=CC2=NSN=C2C(=C1)[N+](=O)[O-]
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InChI |
1S/C6H3N3O2S/c10-9(11)5-3-1-2-4-6(5)8-12-7-4/h1-3H
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InChIKey |
IWQKAMJGVIHECB-UHFFFAOYSA-N
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CAS Number |
CAS 6583-06-8
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PubChem Compound ID |
Target and Pathway | Top | |||
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Target(s) | Glutathione reductase (GR) | Target Info | Inhibitor | [1] |
BioCyc | Glutathione redox reactions II | |||
Glutathione redox reactions I | ||||
KEGG Pathway | Glutathione metabolism | |||
Thyroid hormone synthesis | ||||
Pathwhiz Pathway | Glutamate Metabolism | |||
Glutathione Metabolism | ||||
WikiPathways | Metapathway biotransformation | |||
Sulfation Biotransformation Reaction | ||||
Oxidative Stress | ||||
NRF2 pathway | ||||
Nuclear Receptors Meta-Pathway | ||||
Selenium Micronutrient Network | ||||
Glutathione metabolism |
References | Top | |||
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REF 1 | Specific inhibitors of Plasmodium falciparum thioredoxin reductase as potential antimalarial agents. Bioorg Med Chem Lett. 2006 Apr 15;16(8):2283-92. |
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