Target Poor or Non Binder(s) Information
| Target General Information | Top | ||||
|---|---|---|---|---|---|
| Target ID | T83174 | Target Info | |||
| Target Name | Protein kinase C iota (PRKCI) | ||||
| Synonyms |
nPKC-iota; aPKC-lambda/iota; Protein kinase C iota type; PRKC-lambda/iota; DXS1179E; Atypical protein kinase C-lambda/iota
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| Target Type | Literature-reported Target | ||||
| Gene Name | PRKCI | ||||
| Biochemical Class | Kinase | ||||
| UniProt ID | |||||
| Poor Binders of This Target (in total, 7 binders) | Download | Top | |||
|---|---|---|---|---|---|
| Compound Name |
N'-[2-(1-Methylpyrazol-4-yl)-5,6,7,8-tetrahydro-[1]benzothiolo[2,3-d]pyrimidin-4-yl]ethane-1,2-diamine
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL3728060; SCHEMBL14986765
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| Activity |
IC50 ~ 60000 nM
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[1] | |||
| Compound Name |
Chembl4205739
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Investigative | Compound Info | ||
| Synonyms |
BDBM50455617
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| Activity |
IC50 = 75000 nM
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[2] | |||
| Compound Name |
Chembl4218133
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Investigative | Compound Info | ||
| Synonyms |
BDBM50455622
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| Activity |
IC50 = 95000 nM
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[2] | |||
| Compound Name |
1-(Tert-Butyl)-3-(naphthalen-1-yl)-1H-pyrazolo[3,4-d]pyrimidin-4-amine
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Investigative | Compound Info | ||
| Synonyms |
1-NAPHTHYL PP1; 1-NA-PP1; pp1 analog; 4-Amino-1-tert-butyl-3-(1'-naphthyl)pyrazolo[3,4-d]pyrimidine; 1-(1,1-dimethylethyl)-3-(1-naphthalenyl)-1H-pyrazolo[3,4-d]pyrimidin-4-amine; 1-tert-butyl-3-naphthalen-1-ylpyrazolo[3,4-d]pyrimidin-4-amine; CHEMBL264406; 1-tert-butyl-3-(naphthalen-1-yl)-1H-pyrazolo[3,4-d]pyrimidin-4-amine; C19H19N5; 1-tert-butyl-3-naphthalen-1-yl-1H-pyrazolo[3,4-d]pyrimidin-4-amine; 1-tert-butyl-3-naphthalen-1-yl-1H-pyrazolo[3,4-d]pyrimidin-4-ylamine; 1-Na PP1; 1-NaphthylPP1; NA-PP1; K00047; SCHEMBL173288; 1-NA-PP 1; CTK4E8691; 1-Naphthyl PP1(1-NA-PP1); DTXSID00274446; EX-A867; HMS3266C18; HMS3413H14; HMS3677H14; PP1-AG1872; BCP09108; ZINC2576349; 3272AH; 4-Amino-1-tert-butyl-3-(1'naphthyl)pyrazolo[3,4-d]pyrimidine; BDBM50229961; MFCD03425471; QC-203; s2642; AKOS024457409; ACN-046104; CS-1804; MB02817; KS-00001D85; NCGC00262627-06; AS-56537; HY-13941; AB0094864; PP1 Analog - CAS 221243-82-9; FT-0661645; A13232; InSolution PP1 Analog - CAS 221243-82-9; 425B471; W-201916; BRD-K29542628-001-01-3; Q27123369; 1-t-butyl-3-naphthalen-1-yl-1h-pyrazolo[3,4-d]pyrimidin-4-ylamine; 4-Amino-1-tert-butyl-3-(1''-naphthyl)pyrazolo[3,4-d]pyrimidine; 4-Amino-1-tert-butyl-3-(1?-naphthyl)pyrazolo[3,4-d]pyrimidine; 1-(tert-butyl)-3-(naphthalen-1-yl)-1H-pyrazolo[3,4-d]pyrimidin-4-amine (4); 1H-pyrazolo[3,4-d]pyrimidin-4-amine, 1-(1,1-dimethylethyl)-3-(1-naphthalenyl)-; 1H-Pyrazolo[3,4-d]pyrimidin-4-amine,1-(1,1-dimethylethyl)-3-(1-naphthalenyl)-
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| Activity |
IC50 ~ 100000 nM
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[3] | |||
| Compound Name |
Chembl4202899
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Investigative | Compound Info | ||
| Synonyms |
BDBM50455580
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| Activity |
IC50 = 105000 nM
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[2] | |||
| Compound Name |
Chembl4210601
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Investigative | Compound Info | ||
| Synonyms |
BDBM50455614
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| Activity |
IC50 = 148000 nM
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[2] | |||
| Compound Name |
Chembl4203835
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Investigative | Compound Info | ||
| Synonyms |
BDBM50455615
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| Activity |
IC50 = 188000 nM
|
[2] | |||
| Click to Show/Hide the Information of All Poor Binders | |||||
| Non Binders of This Target (in total, 25 non binders) | Download | Top | |||
|---|---|---|---|---|---|
| Compound Name |
Chembl4218913
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Investigative | Compound Info | ||
| Synonyms |
SCHEMBL99352; BDBM50455579; 4-(4-bromopyrazol-1-yl)-1H-pyrrolo[2,3-b]pyridine; 4-(4-bromo-1H-pyrazol-1-yl)-1H-pyrrolo[2,3-b]pyridine
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| Activity |
IC50 = 201000 nM
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[2] | |||
| Compound Name |
Chembl4204384
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Investigative | Compound Info | ||
| Synonyms |
BDBM50455623
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| Activity |
IC50 = 215000 nM
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[2] | |||
| Compound Name |
Chembl4206942
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Investigative | Compound Info | ||
| Synonyms |
BDBM50455581
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| Activity |
IC50 = 221000 nM
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[2] | |||
| Compound Name |
N-Methyl-(5-pyrid-4-ylthien-2-yl)methylamine
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL4207793; methyl({[5-(pyridin-4-yl)thiophen-2-yl]methyl})amine; CTK5H2534; DTXSID80640448; BDBM50455574; MFCD09879964; SBB093350; ZINC12370807; methyl[(5-(4-pyridyl)(2-thienyl))methyl]amine; N-methyl-1-(5-pyridin-4-ylthiophen-2-yl)methanamine; N-Methyl-1-[5-(pyridin-4-yl)thiophen-2-yl]methanamine; N-METHYL-(5-PYRIDIN-4-YLTHIOPHEN-2-YL)METHYLAMINE
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| Activity |
IC50 = 229000 nM
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[2] | |||
| Compound Name |
Chembl4207181
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Investigative | Compound Info | ||
| Synonyms |
SCHEMBL10125558; BDBM50455578
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| Activity |
IC50 = 371000 nM
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[2] | |||
| Compound Name |
Chembl4214498
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Investigative | Compound Info | ||
| Synonyms |
SCHEMBL12127208; BDBM50455621; 4-pyridin-2-yl-1H-pyrrolo[2,3-b]pyridine
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| Activity |
IC50 = 374000 nM
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[2] | |||
| Compound Name |
Chembl4203536
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Investigative | Compound Info | ||
| Synonyms |
BDBM50455563
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| Activity |
IC50 > 384000 nM
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[2] | |||
| Compound Name |
Chembl4216057
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Investigative | Compound Info | ||
| Synonyms |
BDBM50455618
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| Activity |
IC50 > 384000 nM
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[2] | |||
| Compound Name |
Chembl4211603
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Investigative | Compound Info | ||
| Synonyms |
BDBM50455562
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| Activity |
IC50 > 384000 nM
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[2] | |||
| Compound Name |
1H-Pyrrolo[2,3-b]pyridine-4-carboxamide
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL4202835; SCHEMBL2606616; CTK7D2945; DTXSID40634702; BDBM50455565; MFCD11046289; ZINC19046426; AKOS006309973; DA-18827; FT-0715149; A-5920; 1H-Pyrrolo[2,3-b]pyridine-4-carboxamide, AldrichCPR
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| Activity |
IC50 > 384000 nM
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[2] | |||
| Compound Name |
3-Pyridinecarboxamide, 2-amino-N-phenyl-
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL4203838; 2-aminonicotinanilide; 2-Amino-N-phenylnicotinamide; CTK1G5588; DTXSID40388798; BDBM50455576; AKOS011337330
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| Activity |
IC50 = 424000 nM
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[2] | |||
| Compound Name |
4-Chloro-5-methyl-1H-pyrrolo[2,3-b]pyridine
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Investigative | Compound Info | ||
| Synonyms |
1H-Pyrrolo[2,3-b]pyridine, 4-chloro-5-methyl-; CHEMBL4204389; SCHEMBL12561934; CTK6C3633; DTXSID30649805; BCP21971; 7548AC; BDBM50455612; MFCD09965882; ZINC14401149; AKOS006314751; SB14152; VP11119; PS-13143; DB-029397; CS-0037735; FT-0678351; A-5849; 4-Chloro-5-methyl-1H-pyrrolo[2,3-b]pyridine, AldrichCPR
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| Activity |
IC50 = 452000 nM
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[2] | |||
| Compound Name |
1(2H)-Phthalazinone
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Investigative | Compound Info | ||
| Synonyms |
Phthalazin-1(2H)-one; Phthalazone; Phthalazinone; Phthalazin-1-one; 2H-Phthalazin-1-one; 1-Phthalazinol; 1(2H)Phthalazinone; phthalazin-1-ol; 1-phthalazinone; 1,2-dihydrophthalazin-1-one; UNII-463ZJB0EI2; 463ZJB0EI2; CHEMBL124706; MFCD00006892; 1-Hydroxyphthalazine; 2-hydrophthalazin-1-one; WLN: T66 BVMNJ; 1(2H)-Phthalazinone, 98+%; CCRIS 4860; HSDB 4310; EINECS 204-319-8; NSC 10432; Benzo[d]pyridazin-1(2H)one; 1-oxophthalazine; (2H)-phthalazinone; Phthalazone, 99%; Phthalazinol (9CI); 1-(2h)-phthalazinone; DSSTox_CID_5903; ACMC-209u7u; DSSTox_RID_77965; DSSTox_GSID_25903; SCHEMBL51553; KSC176I3D; ARONIS24088; DTXSID4025903; CTK0H6431; CTK2F5528; IJAPPYDYQCXOEF-UHFFFAOYSA-; ACT05270; ALBB-028398; BCP29580; KS-00000L1P; NSC10432; NSC52567; STR06150; Tox21_200287; ANW-43432; BBL023000; BDBM50106185; NSC-10432; NSC-52567; SBB080598; STL356796; ZINC16890049; AKOS000119448; AKOS001019048; AB03574; MCULE-6184387915; NCGC00091321-01; NCGC00091321-02; NCGC00257841-01; AK-44896; BR-44896; Phthalazone pound>>Phthalazin-1(2H)-one; SC-26978; SY026934; DB-001996; EU-0033708; FT-0631680; P1179; ST45025194; C14473; S-1490; 80196-EP2281818A1; 80196-EP2305250A1; W-60386; W-108514; Q27115758; Z48957540; F0213-0013
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| Activity |
IC50 = 589000 nM
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[2] | |||
| Compound Name |
4-Bromo-1H-pyrrolo[2,3-b]pyridine
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Investigative | Compound Info | ||
| Synonyms |
4-Bromo-7-azaindole; 4-Bromo-7-Azaindol; 1H-PYRROLO[2,3-B]PYRIDINE, 4-BROMO-; 4-bromo-1H-pyrrolo [2,3-b] pyridine; MFCD08272233; CHEMBL4206553; 4-BROMO-1H-PYRROLO-[2,3]PYRIDINE; 4-bromo-1H-pyrrolo(2,3-b)pyridine; PubChem14706; 4-Bromo-7-aza-1H-indole; SCHEMBL99690; KSC497K7L; 4-Bromo-7-azaindole, 96%; 4-bromopyrrolo[2,3-b]pyridine; CTK3J7575; DTXSID90624173; ACN-S002738; ACT02521; BCP00239; CS-B0098; KS-000002SB; ZINC8700530; AB1241; ABBYPHARMA AP-12-10343; ANW-28003; BBL103940; BDBM50455571; CB0117; GEO-03533; RW3724; SBB054657; STL557750; WT1414; AKOS005258170; 4-bromo-1 H-pyrrolo[2,3-b]pyridine; 4-bromo-1H-pyrrolo [2,3-b]pyridine; AC-5217; AS07112; CM14081; FG-0210; LS20490; MCULE-2566621001; PB31039; QC-2853; 4-bromanyl-1H-pyrrolo[2,3-b]pyridine; 348640-06-2 4-Bromo-7-azaindole; AK-24318; BC003915; BR-24318; SC-14342; SY005529; AB0021108; DB-028756; A6126; AM20051104; FT-0649538; V2314; EN300-28960; C-6137; Z-8112; 72467-EP2308867A2; 72470-EP2308867A2; 72470-EP2308870A2; 640B062; A822449; W-202429
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| Activity |
IC50 = 615000 nM
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[2] | |||
| Compound Name |
5-Aminobenzimidazole
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Investigative | Compound Info | ||
| Synonyms |
6-Aminobenzimidazole; 1h-benzo[d]imidazol-5-amine; 1H-Benzimidazol-5-amine; 1H-Benzo[d]imidazol-6-amine; 1H-Benzoimidazol-5-ylamine; 1h-1,3-benzimidazol-5-amine; 3H-benzimidazol-5-amine; 3H-BENZOIMIDAZOL-5-YLAMINE; 1H-1,3-benzodiazol-5-amine; Benzimidazole, 6-amino-; 1H-Benzimidazol-6-amine; BENZIMIDAZOLE, 5-AMINO-; 1H-1,3-benzodiazol-6-amine; Benzimidazol-5-amine; UNII-7L7289019S; 1H-benzimidazol-5-ylamine; CHEMBL1617811; 5-AMINO-1H-BENZOIMIDAZOLE; 1H-BENZOIMIDAZOLE-5-YLAMINE; Benzimidazol-5-ylamine; 7L7289019S; benzimidazolamine; 5-amino-1h-benzimidazole; EINECS 213-279-0; NSC 231612; 3H-benzo[d]imidazol-5-amine; 1H-Benzimidazol-5-amine (9CI); 5-aminobenzimdazole; 5-aminobenzimidazol; zlchem 571; 5-amino benzimidazole; 5-amino-benzimidazole; benzimidazole-5-ylamine; benzimidazole-6-ylamine; PubChem20258; 1H-benzimidazole-6-amine; 1H-benzoimidazol-5-amine; 3H-benzimidazol-5-ylamine; 6-Aminobenzimidazole, 95%; 1H-Benzimidazol-6-amine #; Oprea1_342288; Oprea1_610116; (1H-benzimidazol-5yl) amine; SCHEMBL115965; 1H-13-Benzimidazol-5-amine; 5-amino-1H-benzo[d]imidazole; 5-aminobenzimidazole, AldrichCPR; CTK3I7234; DTXSID70239406; ZLD0008; ACN-S003674; ACT05702; ACT10631; ALBB-023267; BCP11467; KS-000012GQ; KS-00001UQ5; ZINC4692941; ANW-48192; BBL011727; BDBM50455561; MFCD00465258; MFCD00831692; NSC231612; SBB010145; STK731665; AKOS000111798; AKOS003574217; AC-2803; AS06676; MCULE-4931848584; NSC-231612; PS-4509; QC-3409; VI10165; WT81900; NCGC00184564-01; NCGC00184564-02; AK-36914; BR-36914; SC-21897; SY002960; 5-AMINOBENZIMIDAZOLE DIHYDROCHLORIDE; AB0062234; ST4147468; BB 0217003; CS-0096864; FT-0620009; FT-0655568; 2P-043; A11004; C-5815; X-4158; AH-034/32844026; J-519689; Q27268505; F2158-1066; Z1741960823
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| Activity |
IC50 = 728000 nM
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[2] | |||
| Compound Name |
2,3-Dihydro-1-benzofuran-5-carbothioamide
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Investigative | Compound Info | ||
| Synonyms |
2,3-DIHYDROBENZO[B]FURAN-5-CARBOTHIOAMIDE; 2,3-Dihydrobenzo[b]furan-5-thioamide; 2,3-dihydrobenzofuran-5-carbothioamide; CHEMBL4212691; Maybridge1_008543; SCHEMBL3544882; CTK1C1532; HMS565M07; DTXSID40371140; 2,3-dihydrobenzofuran-5-thioamide; ZINC4284725; BDBM50455619; MFCD00728868; SBB089569; AKOS009159076; MCULE-4415042136; NE45028; VZ22275; 5-Benzofurancarbothioamide, 2,3-dihydro-; SC-58346; FT-0609654; A820537; amino-2,3-dihydrobenzo[b]furan-5-ylmethane-1-thione
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| Activity |
IC50 = 927000 nM
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[2] | |||
| Compound Name |
4-Phenyl-[1]benzofuro[2,3-b]pyridine-3,6-diol
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL2163772; BDBM50395892
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| Activity |
Ki > 1000000 nM
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[4] | |||
| Compound Name |
N-(4-Methoxybenzyl)benzofuro[2,3-b]pyridin-4-amine
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL1290072; BDBM50331612
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| Activity |
Ki > 1000000 nM
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[5] | |||
| Compound Name |
4-Chloro-7-azaindole
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Investigative | Compound Info | ||
| Synonyms |
4-chloro-1H-pyrrolo[2,3-b]pyridine; MFCD08272232; 1H-PYRROLO[2,3-B]PYRIDINE, 4-CHLORO-; 4-Chloro-7-azaindole, 97%; CHEMBL4204893; 4-chlor-1H-pyrrolo[2,3-b]pyridin; 4-choro-7-azaindole; PubChem17277; ACMC-1AY8O; KSC494A8L; SCHEMBL100651; AMOT0920; 4-chloropyrrolo[2,3-b]pyridine; CTK3J4085; DTXSID50464294; ACN-S002668; ACT03614; CS-B0097; EBD18635; KS-000001JG; ZINC8699969; ANW-32233; BBL101292; BDBM50455573; CC0105; EBD472513; QC-603; RW3131; SBB086870; STL555088; 1H-Pyrrolo[2,3-b]pyridine,4-chloro; AKOS004910656; AC-5049; AS07111; CM14082; CS-W000189; LS40318; MCULE-2053204965; PB29499; VP11069; 4-chloro-1-H-pyrrolo[2,3-b]pyridine; 4-Chloro-1H-pyrrolo[2,3-b]-pyridine; 4-chloranyl-1H-pyrrolo[2,3-b]pyridine; AK-24319; BP-13250; BR-24319; SC-22875; SY004661; AB0003536; DB-024435; AM20061315; FT-0642107; FT-0648837; X3065; C-8186; N-(3-Chloro-2-methylpropyl)-N-methylformamide; 052C283; 4Z-5015; A830464; AN-584/43416898; W-203076; W-203973; F2108-0145
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| Activity |
IC50 = 1300000 nM
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[2] | |||
| Compound Name |
1-Methyl-1H-indol-5-amine
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Investigative | Compound Info | ||
| Synonyms |
5-Amino-1-N-methylindole; 1-methylindol-5-amine; 1-Methyl-1H-indol-5-ylamine; 1h-indol-5-amine, 1-methyl-; 5-amino-1-methyl-1h-indole; 1-methyl-5-amino-1h-indole; 1-methylindole-5-ylamine; CHEMBL4216063; MFCD03839873; PubChem9381; 1-methyl-5-aminoindole; 5-amino-1-methylindole; 5-amino-1-methyl-indole; (1-Methylindol-5-yl)amine; KSC500S1T; SCHEMBL721707; 1-Methyl-1H-indole-5-amine; ACMC-20981i; 1H-Indol-5-amine,1-methyl-; CTK4A0919; KS-00000ILS; DTXSID60377760; HMS1702C02; ACT04946; ZINC2512959; ANW-14692; BDBM50455628; SBB010309; AKOS000505691; 5-amino-1-N-Methylindole, AldrichCPR; AC-6688; AS07117; CS-W021349; MCULE-9807567275; PS-5817; SB15029; AK-32682; BR-32682; SC-46139; SY063835; AB0013364; BB 0261976; FT-0630144; ST50321730; A-1878; 308A974; Q-102911; F5608-0075
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| Activity |
IC50 = 1312000 nM
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[2] | |||
| Compound Name |
1-(3-Amino-4-(methylamino)phenyl)ethanone
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Investigative | Compound Info | ||
| Synonyms |
1-[3-amino-4-(methylamino)phenyl]ethanone; 1-[3-Amino-4-(methylamino)phenyl]ethan-1-one; CHEMBL4204735; 1-[3-amino-4-(methylamino)phenyl]-1-ethanone; 3'-Amino-4'-(methylamino)acetophenone; 1-(3-Amino-4-methylamino-phenyl)-ethanone; Ethanone,1-[3-amino-4-(methylamino)phenyl]-; 1-(3-amino-4-(methylamino)phenyl)ethan-1-one; SCHEMBL2245773; CTK4D7700; KS-00003QPG; DTXSID80381541; ZINC161916; BDBM50455575; CCG-53873; MFCD03407301; SBB055100; AKOS006229224; PS-4425; 1-(3-Amino-4-methylaminophenyl)ethanone; 1-acetyl-3-amino-4-(methylamino)benzene; AM807183; AB0040443; DB-065333; FT-0607120; Y8046; A-7274; Ethanone, 1-[3-amino-4-(methylamino)phenyl]-; SR-01000643006-1; W-206286; 1-[3-amino-4-(methylamino)phenyl]-1-ethanone, AldrichCPR
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| Activity |
IC50 = 1423000 nM
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[2] | |||
| Compound Name |
1-(2,6-Dihydroxy-3-propylphenyl)ethanone
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Investigative | Compound Info | ||
| Synonyms |
1-(2,6-dihydroxy-3-propylphenyl)ethan-1-one; CHEMBL3274344; ethanone, 1-(2,6-dihydroxy-3-propylphenyl)-; SCHEMBL9739914; CTK4J8345; DTXSID70349170; ZINC157848; BDBM50455577; DA-20090; FT-0715274
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| Activity |
IC50 = 1556000 nM
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[2] | |||
| Compound Name |
4-Amino-2-[(Diethylamino)Methyl]Phenol
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Investigative | Compound Info | ||
| Synonyms |
4-amino-2-(diethylaminomethyl)phenol; 4-AMINO-ALPHA-DIETHYLAMINO-O-CRESOL; Phenol, 4-amino-2-[(diethylamino)methyl]-; 4-amino-2-((diethylamino)methyl)phenol; CHEMBL4215993; Oprea1_209705; SCHEMBL111109; 4-Amino-a-diethylamino-o-cresol; CTK1G4858; ZINC56448; DTXSID80328294; ALBB-024952; 4-hydroxy-3-diethylaminomethylaniline; BDBM50455616; SBB005870; AKOS004121517; 4-Amino-.alpha.-diethylamino-o-cresol; MCULE-3769488677; ST081339; FT-0692404; R1253; J-800223; phenol, 4-amino-2-[(diethylamino)methyl]-, dihydrochloride
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| Activity |
IC50 = 1570000 nM
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[2] | |||
| Compound Name |
6-Hydroxy-1-tetralone
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Investigative | Compound Info | ||
| Synonyms |
6-Hydroxy-3,4-dihydronaphthalen-1(2H)-one; 6-Hydroxy-3,4-dihydro-1(2H)-naphthalenone; 2,5-Dimethoxy Naphthalene; 6-hydroxytetralone; MFCD00156670; 6-hydroxy-1,2,3,4-tetrahydronaphthalen-1-one; 6-hydroxy-3,4-dihydro-2H-naphthalen-1-one; 1(2H)-NAPHTHALENONE, 3,4-DIHYDRO-6-HYDROXY-; CHEMBL3288306; 6-hydroxy-2,3,4-trihydronaphthalen-1-one; 6-Hydroxy-1-tetralone, 98%; 6-hydroxytetralin-1-one; 1-Tetralon-6-ol; 6-hydroxy tetralone; 6-hydroxy-1-teralone; ACMC-1CSWP; KSC497M4H; SCHEMBL228128; AMOT0731; CTK3J7643; DTXSID30405488; EBD22462; KS-00000C0F; ZINC4108295; 4212AB; BBL101389; BDBM50017515; SBB066989; STL555185; AKOS005258189; AC-1123; CS-W004882; MB00784; MCULE-4459132778; MS-2425; VZ30773; AK-29202; SC-26643; SY003653; 6-hydroxy-1,2,3,4-tetrahydronaphtalenone; AB0066271; DB-001000; 3,4-dihydro-6-hydroxy-2H-naphthalen-1-one; AM20040236; FT-0648908; 5-(Bromomethyl)-3-(3-fluorophenyl)isoxazole; EN300-58857; L-1858; 470H506; 6-Hydroxy-3,4-dihydro-1(2H)-naphthalenone, 98%; J-019722; J-518793; Z1245633417
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| Activity |
IC50 = 1677000 nM
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[2] | |||
| Compound Name |
(3-Pyrid-4-ylphenyl)methanol
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Investigative | Compound Info | ||
| Synonyms |
(3-pyridin-4-ylphenyl)methanol; [3-(pyridin-4-yl)phenyl]methanol; CHEMBL4211034; Benzenemethanol,3-(4-pyridinyl)-; (3-(Pyridin-4-yl)phenyl)methanol; 3-(Pyridin-4-yl)benzyl alcohol; SCHEMBL12641314; CTK5F5197; DTXSID00383784; ZINC4200682; (3-(4-pyridyl)phenyl)methan-1-ol; BDBM50455613; MFCD06659083; SBB090289; AKOS006345972; (3-pyrid-4-ylphenyl)methanol, AldrichCPR; Y4296; J-501087
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| Activity |
IC50 = 2216000 nM
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[2] | |||
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| References | Top | ||||
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| REF 1 | WO patent application no. 2013078126A1, THIENOPYRIMIDINE INHIBITORS OF ATYPICAL PROTEIN KINASE C | ||||
| REF 2 | Fragment-Based Drug Discovery of Potent Protein Kinase C Iota Inhibitors. J Med Chem. 2018 May 24;61(10):4386-4396. | ||||
| REF 3 | Protein kinase C epsilon regulates gamma-aminobutyrate type A receptor sensitivity to ethanol and benzodiazepines through phosphorylation of gamma2... J Biol Chem. 2007 Nov 9;282(45):33052-63. | ||||
| REF 4 | Multitargeted drug development: Discovery and profiling of dihydroxy substituted 1-aza-9-oxafluorenes as lead compounds targeting Alzheimer disease relevant kinases. Bioorg Med Chem Lett. 2012 Nov 15;22(22):6914-8. | ||||
| REF 5 | Discovery and selectivity-profiling of 4-benzylamino 1-aza-9-oxafluorene derivatives as lead structures for IGF-1R inhibitors. Bioorg Med Chem Lett. 2010 Dec 1;20(23):6915-9. | ||||
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