TTD_Target_ID Target_Name TTD_Drug_ID Drug_Name Drug_Highest_Status Drug_PubchemID Molecular_Formula Molecular_Weight Canonical_SMILES Activity Binder_Type T83174 Protein kinase C iota B01DUN Chembl4218913 Investigative 57477672 C10H7BrN4 263.09 C1=CNC2=NC=CC(=C21)N3C=C(C=N3)Br IC50 = 201000 nM Non binder T83174 Protein kinase C iota B1CBP4 N-Methyl-(5-pyrid-4-ylthien-2-yl)methylamine Investigative 24229745 C11H12N2S 204.29 CNCC1=CC=C(S1)C2=CC=NC=C2 IC50 = 229000 nM Non binder T83174 Protein kinase C iota B6IEX3 Chembl4203536 Investigative 145977027 C23H17N5O2 395.4 COC1=CC2=C(CN(C2=O)C3=C4C=C(C=CN4N=C3)C5=C6C=CNC6=NC=C5)C=C1 IC50 > 384000 nM Non binder T83174 Protein kinase C iota B6J7GF 3-Pyridinecarboxamide, 2-amino-N-phenyl- Investigative 3039701 C12H11N3O 213.23 C1=CC=C(C=C1)NC(=O)C2=C(N=CC=C2)N IC50 = 424000 nM Non binder T83174 Protein kinase C iota B6PIM2 Chembl4216057 Investigative 145974662 C15H12N4 248.28 CN1C=NC2=C1C=CC(=C2)C3=C4C=CNC4=NC=C3 IC50 > 384000 nM Non binder T83174 Protein kinase C iota B8M9UG 5-Aminobenzimidazole Investigative 13623 C7H7N3 133.15 C1=CC2=C(C=C1N)NC=N2 IC50 = 728000 nM Non binder T83174 Protein kinase C iota BA28XG Chembl4211603 Investigative 145967167 C15H11N3 233.27 C1=CC(=CC2=C1C=CN2)C3=C4C=CNC4=NC=C3 IC50 > 384000 nM Non binder T83174 Protein kinase C iota BD0C5R 1-(3-Amino-4-(methylamino)phenyl)ethanone Investigative 2779769 C9H12N2O 164.2 CC(=O)C1=CC(=C(C=C1)NC)N IC50 = 1423000 nM Non binder T83174 Protein kinase C iota BEJ62B 4-Phenyl-[1]benzofuro[2,3-b]pyridine-3,6-diol Investigative 51000510 C17H11NO3 277.27 C1=CC=C(C=C1)C2=C3C4=C(C=CC(=C4)O)OC3=NC=C2O Ki > 1000000 nM Non binder T83174 Protein kinase C iota BFRW53 1-Methyl-1H-indol-5-amine Investigative 2769564 C9H10N2 146.19 CN1C=CC2=C1C=CC(=C2)N IC50 = 1312000 nM Non binder T83174 Protein kinase C iota BFZH93 4-Chloro-5-methyl-1H-pyrrolo[2,3-b]pyridine Investigative 26076409 C8H7ClN2 166.61 CC1=CN=C2C(=C1Cl)C=CN2 IC50 = 452000 nM Non binder T83174 Protein kinase C iota BG6LK4 2,3-Dihydro-1-benzofuran-5-carbothioamide Investigative 2736118 C9H9NOS 179.24 C1COC2=C1C=C(C=C2)C(=S)N IC50 = 927000 nM Non binder T83174 Protein kinase C iota BHE30B 4-Amino-2-[(Diethylamino)Methyl]Phenol Investigative 408991 C11H18N2O 194.27 CCN(CC)CC1=C(C=CC(=C1)N)O IC50 = 1570000 nM Non binder T83174 Protein kinase C iota BJ57YZ N-(4-Methoxybenzyl)benzofuro[2,3-b]pyridin-4-amine Investigative 50908681 C19H16N2O2 304.3 COC1=CC=C(C=C1)CNC2=C3C4=CC=CC=C4OC3=NC=C2 Ki > 1000000 nM Non binder T83174 Protein kinase C iota BJQ5S4 Chembl4206942 Investigative 145978821 C14H10N4 234.26 C1=CNC2=NC=CC(=C21)C3=CC4=CN=CN4C=C3 IC50 = 221000 nM Non binder T83174 Protein kinase C iota BJZ54Q 1H-Pyrrolo[2,3-b]pyridine-4-carboxamide Investigative 23515094 C8H7N3O 161.16 C1=CNC2=NC=CC(=C21)C(=O)N IC50 > 384000 nM Non binder T83174 Protein kinase C iota BL8I4R 4-Chloro-7-azaindole Investigative 11389493 C7H5ClN2 152.58 C1=CNC2=NC=CC(=C21)Cl IC50 = 1300000 nM Non binder T83174 Protein kinase C iota BS9H2X 1(2H)-Phthalazinone Investigative 8394 C8H6N2O 146.15 C1=CC=C2C(=C1)C=NNC2=O IC50 = 589000 nM Non binder T83174 Protein kinase C iota BSI1E2 Chembl4207181 Investigative 57482985 C14H11N3O 237.26 C1=CC(=CC(=C1)C(=O)N)C2=C3C=CNC3=NC=C2 IC50 = 371000 nM Non binder T83174 Protein kinase C iota BUO7K9 (3-Pyrid-4-ylphenyl)methanol Investigative 2795564 C12H11NO 185.22 C1=CC(=CC(=C1)C2=CC=NC=C2)CO IC50 = 2216000 nM Non binder T83174 Protein kinase C iota BWR85N 1-(2,6-Dihydroxy-3-propylphenyl)ethanone Investigative 643398 C11H14O3 194.23 CCCC1=C(C(=C(C=C1)O)C(=O)C)O IC50 = 1556000 nM Non binder T83174 Protein kinase C iota BYCR78 4-Bromo-1H-pyrrolo[2,3-b]pyridine Investigative 22273643 C7H5BrN2 197.03 C1=CNC2=NC=CC(=C21)Br IC50 = 615000 nM Non binder T83174 Protein kinase C iota BZ30JB 6-Hydroxy-1-tetralone Investigative 4679494 C10H10O2 162.18 C1CC2=C(C=CC(=C2)O)C(=O)C1 IC50 = 1677000 nM Non binder T83174 Protein kinase C iota BZ7A6L Chembl4204384 Investigative 145975823 C15H12N4 248.28 CC1=NC2=C(N1)C=C(C=C2)C3=C4C=CNC4=NC=C3 IC50 = 215000 nM Non binder T83174 Protein kinase C iota BZB3V9 Chembl4214498 Investigative 23515103 C12H9N3 195.22 C1=CC=NC(=C1)C2=C3C=CNC3=NC=C2 IC50 = 374000 nM Non binder