Target Poor or Non Binder(s) Information
| Target General Information | Top | ||||
|---|---|---|---|---|---|
| Target ID | T66396 | Target Info | |||
| Target Name | Eukaryotic translation initiation factor 2-alpha kinase 4 (EIF2AK4) | ||||
| Synonyms |
eIF-2-alpha kinase GCN2; KIAA1338; GCN2-like protein; GCN2
Click to Show/Hide
|
||||
| Target Type | Literature-reported Target | ||||
| Gene Name | EIF2AK4 | ||||
| UniProt ID | |||||
| Poor Binders of This Target (in total, 2 binders) | Download | Top | |||
|---|---|---|---|---|---|
| Compound Name |
2-[5-(4-Amino-2,7-dimethylpyrrolo[2,3-d]pyrimidin-5-yl)-2,3-dihydroindol-1-yl]-1-[3-fluoro-5-(trifluoromethyl)phenyl]ethanone
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3407863; BDBM50072038
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 50000 nM
|
[1] | |||
| Compound Name |
4-[2-Amino-4-methyl-3-[2-(trifluoromethyl)-1,3-benzothiazol-6-yl]benzoyl]-1-methyl-2,5-diphenylpyrazol-3-one
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3407861; BDBM50072035
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 50000 nM
|
[1] | |||
| References | Top | ||||
|---|---|---|---|---|---|
| REF 1 | Discovery of 1H-pyrazol-3(2H)-ones as potent and selective inhibitors of protein kinase R-like endoplasmic reticulum kinase (PERK). J Med Chem. 2015 Feb 12;58(3):1426-41. | ||||
If You Find Any Error in Data or Bug in Web Service, Please Kindly Report It to Dr. Zhou and Dr. Zhang.