TTD_Target_ID Target_Name TTD_Drug_ID Drug_Name Drug_Highest_Status Drug_PubchemID Molecular_Formula Molecular_Weight Canonical_SMILES Activity Binder_Type T66396 Eukaryotic translation initiation factor 2-alpha kinase 4 BNO90Y 2-[5-(4-Amino-2,7-dimethylpyrrolo[2,3-d]pyrimidin-5-yl)-2,3-dihydroindol-1-yl]-1-[3-fluoro-5-(trifluoromethyl)phenyl]ethanone Investigative 118730423 C25H21F4N5O 483.5 CC1=NC(=C2C(=CN(C2=N1)C)C3=CC4=C(C=C3)N(CC4)CC(=O)C5=CC(=CC(=C5)F)C(F)(F)F)N IC50 ~ 50000 nM Poor binder T66396 Eukaryotic translation initiation factor 2-alpha kinase 4 BZ7X0R 4-[2-Amino-4-methyl-3-[2-(trifluoromethyl)-1,3-benzothiazol-6-yl]benzoyl]-1-methyl-2,5-diphenylpyrazol-3-one Investigative 118730422 C32H23F3N4O2S 584.6 CC1=C(C(=C(C=C1)C(=O)C2=C(N(N(C2=O)C3=CC=CC=C3)C)C4=CC=CC=C4)N)C5=CC6=C(C=C5)N=C(S6)C(F)(F)F IC50 ~ 50000 nM Poor binder