Target Poor or Non Binder(s) Information
| Target General Information | Top | ||||
|---|---|---|---|---|---|
| Target ID | T65483 | Target Info | |||
| Target Name | Carboxypeptidase M (CPM) | ||||
| Synonyms |
Human carboxypeptidase M
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| Target Type | Literature-reported Target | ||||
| Gene Name | CPM | ||||
| Biochemical Class | Peptidase | ||||
| UniProt ID | |||||
| Poor Binders of This Target (in total, 9 binders) | Download | Top | |||
|---|---|---|---|---|---|
| Compound Name |
DL-benzylsuccinic acid
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Investigative | Compound Info | ||
| Synonyms |
2-Benzylsuccinic acid; 884-33-3; Benzylsuccinic acid; 2-benzylbutanedioic acid; DL-Benzylsuccinic acid; alpha-Benzylsuccinic acid; 36092-42-9; (phenylmethyl)butanedioic acid; beta-carboxybenzenebutanoic acid; D,L-Benzylsuccinic Acid; Butanedioic acid,2-(phenylmethyl)-; NSC20708; .alpha.-Benzylsuccinic acid; CHEMBL151284; CHEBI:16054; GTOFKXZQQDSVFH-UHFFFAOYSA-N; MFCD00055798; Benzenebutanoic acid, .beta.-carboxy-; 2-Benzyl-succinic acid; NSC-20708; NSC 20708; mono benzyl succinic acid; AC1L1GVE; 2-Benzylsuccinic acid #
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| Activity |
IC50 ~ 50000 nM
|
[1] | |||
| Compound Name |
alpha-Benzyl-1H-imidazole-4-acetic acid
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL33352; BDBM50100009; 2-(1H-Imidazol-4-yl)-3-phenyl-propionic acid; 2-(3H-Imidazol-4-yl)-3-phenyl-propionic acid
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| Activity |
IC50 ~ 50000 nM
|
[1] | |||
| Compound Name |
3-(6-Aminopyridin-3-yl)-2-(1-ethylimidazol-4-yl)propanoic Acid
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL358017; SCHEMBL7260843; BDBM50135940; 3-(6-Amino-pyridin-3-yl)-2-(1-ethyl-1H-imidazol-4-yl)-propionic acid
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| Activity |
IC50 ~ 50000 nM
|
[1] | |||
| Compound Name |
3-(6-Amino-pyridin-3-yl)-2-(1-benzyl-1H-imidazol-4-yl)-propionic acid
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL436425; SCHEMBL7260136; BDBM50135935
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| Activity |
IC50 ~ 50000 nM
|
[1] | |||
| Compound Name |
3-(6-Aminopyridin-3-yl)-2-(1-methylimidazol-4-yl)propanoic Acid
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL344949; SCHEMBL7257116; BDBM50135937; 3-(6-Amino-pyridin-3-yl)-2-(1-methyl-1H-imidazol-4-yl)-propionic acid
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| Activity |
IC50 ~ 50000 nM
|
[1] | |||
| Compound Name |
3-(6-Amino-pyridin-3-yl)-2-[1-(3-methyl-butyl)-1H-imidazol-4-yl]-propionic acid
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL68399; BDBM50135934
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| Activity |
IC50 ~ 50000 nM
|
[1] | |||
| Compound Name |
3-Pyridinepropanoic acid, 6-amino-alpha-1H-imidazol-5-yl-
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL302067; SCHEMBL2537437; 3-(6-aminopyridin-3-yl)-2-(1H-imidazol-5-yl)propanoic acid; BDBM50135933; DA-05473; FT-0737488; 3-(6-aminopyridin-3-yl)-2-(1H-imidazol-4-yl)propionic acid; 3-(6-Amino-pyridin-3-yl)-2-(1H-imidazol-4-yl)-propionic acid
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| Activity |
IC50 ~ 50000 nM
|
[1] | |||
| Compound Name |
3-(6-Amino-pyridin-3-yl)-2-(1-butyl-1H-imidazol-4-yl)-propionic acid
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL149680; SCHEMBL7261800; BDBM50135936
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| Activity |
IC50 ~ 50000 nM
|
[1] | |||
| Compound Name |
3-(6-Aminopyridin-3-yl)-2-(1-propan-2-ylimidazol-4-yl)propanoic Acid
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL356252; SCHEMBL7256437; BDBM50135938; 3-(6-Amino-pyridin-3-yl)-2-(1-isopropyl-1H-imidazol-4-yl)-propionic acid
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| Activity |
IC50 ~ 50000 nM
|
[1] | |||
| Click to Show/Hide the Information of All Poor Binders | |||||
| References | Top | ||||
|---|---|---|---|---|---|
| REF 1 | Synthesis and evaluation of imidazole acetic acid inhibitors of activated thrombin-activatable fibrinolysis inhibitor as novel antithrombotics. J Med Chem. 2003 Dec 4;46(25):5294-7. | ||||
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