TTD_Target_ID Target_Name TTD_Drug_ID Drug_Name Drug_Highest_Status Drug_PubchemID Molecular_Formula Molecular_Weight Canonical_SMILES Activity Binder_Type T65483 Carboxypeptidase M B2CW8R alpha-Benzyl-1H-imidazole-4-acetic acid Investigative 10465893 C12H12N2O2 216.24 C1=CC=C(C=C1)CC(C2=CN=CN2)C(=O)O IC50 ~ 50000 nM Poor binder T65483 Carboxypeptidase M B5ZK1D 3-(6-Aminopyridin-3-yl)-2-(1-ethylimidazol-4-yl)propanoic Acid Investigative 9813856 C13H16N4O2 260.29 CCN1C=C(N=C1)C(CC2=CN=C(C=C2)N)C(=O)O IC50 ~ 50000 nM Poor binder T65483 Carboxypeptidase M B6L9YT 3-(6-Amino-pyridin-3-yl)-2-(1-benzyl-1H-imidazol-4-yl)-propionic acid Investigative 9966944 C18H18N4O2 322.4 C1=CC=C(C=C1)CN2C=C(N=C2)C(CC3=CN=C(C=C3)N)C(=O)O IC50 ~ 50000 nM Poor binder T65483 Carboxypeptidase M B7H2NF 3-(6-Aminopyridin-3-yl)-2-(1-methylimidazol-4-yl)propanoic Acid Investigative 9942902 C12H14N4O2 246.27 CN1C=C(N=C1)C(CC2=CN=C(C=C2)N)C(=O)O IC50 ~ 50000 nM Poor binder T65483 Carboxypeptidase M B7XR6J 3-(6-Amino-pyridin-3-yl)-2-[1-(3-methyl-butyl)-1H-imidazol-4-yl]-propionic acid Investigative 9926432 C16H22N4O2 302.37 CC(C)CCN1C=C(N=C1)C(CC2=CN=C(C=C2)N)C(=O)O IC50 ~ 50000 nM Poor binder T65483 Carboxypeptidase M B8Z0WK 3-Pyridinepropanoic acid, 6-amino-alpha-1H-imidazol-5-yl- Investigative 9837547 C11H12N4O2 232.24 C1=CC(=NC=C1CC(C2=CN=CN2)C(=O)O)N IC50 ~ 50000 nM Poor binder T65483 Carboxypeptidase M BGSK96 3-(6-Amino-pyridin-3-yl)-2-(1-butyl-1H-imidazol-4-yl)-propionic acid Investigative 9857137 C15H20N4O2 288.34 CCCCN1C=C(N=C1)C(CC2=CN=C(C=C2)N)C(=O)O IC50 ~ 50000 nM Poor binder T65483 Carboxypeptidase M BZ0XU8 3-(6-Aminopyridin-3-yl)-2-(1-propan-2-ylimidazol-4-yl)propanoic Acid Investigative 9943447 C14H18N4O2 274.32 CC(C)N1C=C(N=C1)C(CC2=CN=C(C=C2)N)C(=O)O IC50 ~ 50000 nM Poor binder T65483 Carboxypeptidase M D06LNX DL-benzylsuccinic acid Investigative 3858 C11H12O4 208.21 C1=CC=C(C=C1)CC(CC(=O)O)C(=O)O IC50 ~ 50000 nM Poor binder