Target Poor or Non Binder(s) Information
| Target General Information | Top | ||||
|---|---|---|---|---|---|
| Target ID | T63816 | Target Info | |||
| Target Name | Histone deacetylase 4 (HDAC4) | ||||
| Synonyms |
KIAA0288; HD4
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| Target Type | Clinical trial Target | ||||
| Gene Name | HDAC4 | ||||
| Biochemical Class | Carbon-nitrogen hydrolase | ||||
| UniProt ID | |||||
| Poor Binders of This Target (in total, 185 binders) | Download | Top | |||
|---|---|---|---|---|---|
| Compound Name |
Vorinostat
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|
Approved | Compound Info | ||
| Synonyms |
NHNPODA; SAHA; SHH; Zolinza; Merck brand of Vorinostat; OCTANEDIOIC ACID HYDROXYAMIDE PHENYLAMIDE; SAHA cpd; Suberanilohydroxamic acid; Suberoylanilide hydroxamic acid; Vorinostat MSD; Vorinostat [USAN]; M344; MK0683; SKI390; WIN64652; MK-0683; SAHA, Suberoylanilide hydroxamic acid; SW-064652; Zolinza (TN); Vorinostat (JAN/USAN); N1-hydroxy-N8-phenyloctanediamide; Zolinza, MK-0683, SAHA; N'-hydroxy-N-phenyloctanediamide; N-Hydroxy-N'-phenyl octanediamide; N-Hyrdroxy-N'-phenyloctanediamide; N-hydroxy-N'-phenyloctanediamide; N-hydroxy-N'-phenyl-octane-1,8-diotic acid diamide; Vorinostat (HDAC inhibitor)
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| Activity |
IC50 ~ 50000 nM
|
[1] | |||
| Compound Name |
Romidepsin
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Approved | Compound Info | ||
| Synonyms |
Chromadax; Istodax; Antibiotic FR 901228; FK 228; FK228; FR 901228; FR901228; HDInhib_000006; Chromadax (TN); FK-228; FK-901228; FR-901228; Istodax (TN); Romidepsin (USAN); Cyclo((2Z)-2-amino-2-butenoyl-L-valyl-(3S,4E)-3-hydroxy-7-mercapto-4-heptenoyl-D-valyl-D-cysteinyl), cyclic (35)-disulfide; L-Valine, N-((3S,4E)-3-hydroxy-7-mercapto-1-oxo-4-heptenyl)-D-valyl-D-cysteinyl-(2Z)-2-amino-2-butenoxyl-, (4-1)-lactone, cyclic (1-2)-disulfide; (1S,4S,7Z,10S,16E,21R)-7-Ethylidene-4,21-bis(1-methylethyl)-2-oxa-12,13-dithia-5,8,20,23-tetraazabicyclo(8.7.6)tricos-16-ene-3,6,9,19,22-pentone; (1S,4S,7Z,10S,16E,21R)-7-ethylidene-4,21-di(propan-2-yl)-2-oxa-12,13-dithia-5,8,20,23-tetraazabicyclo[8.7.6]tricos-16-ene-3,6,9,19,22-pentone; (1S,4S,7Z,10S,16E,21R)-7-ethylidene-4,21-di(propan-2-yl)-2-oxa-12,13-dithia-5,8,20,23-tetrazabicyclo[8.7.6]tricos-16-ene-3,6,9,19,22-pentone
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|
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| Activity |
IC50 ~ 50000 nM
|
[2] | |||
| Compound Name |
SNDX-275
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|
Phase 3 | Compound Info | ||
| Synonyms |
Entinostat; Histone Deacetylase Inhibitor I; IN1470; MS 275; SNDX 275; MS 27-275; Ms-275; Entinostat (USAN/INN); MS-27-275; Pyridin-3-ylmethyl 4-(2-aminophenylcarbamoyl)benzylcarbamate; Pyridin-3-ylmethyl N-[[4-[(2-aminophenyl)carbamoyl]phenyl]methyl]carbamate; Pyridin-3-ylmethyl {4-[(2-aminophenyl)carbamoyl]benzyl}carbamate; Pyridin-3-ylmethyl{4-[(2-aminophenyl)carbamoyl]benzyl}carbamate; Carbamic acid, [[4-[[(2-aminophenyl)amino]carbonyl]phenyl] methyl]-, 3-pyridinylmethyl ester; Carbamic acid, [[4-[[(2-aminophenyl)carbaonyl]phenyl]methyl]-, 3-pyridinylmethyl ester; Entinostat, SNDX-275, MS-27-275, MS-275; N-(2-Aminophenyl)-4-[N-(pyridin-3-yl-methoxycarbonyl)aminomethyl]benzamide; N-(2-aminophenyl)-4-(N-(pyridin-3-ylmethoxycarbonyl)aminomethyl)benzamide; Carbamic acid, ((4-(((2-aminophenyl)amino)carbonyl)phenyl)methyl)-, 3-pyridinylmethyl ester; 3-Pyridinylmethyl ((4-(((2-aminophenyl)amino)carbonyl)phenyl)methyl)carbamate
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| Activity |
IC50 ~ 50000 nM
|
[1] | |||
| Compound Name |
RG-2833
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Phase 1 | Compound Info | ||
| Synonyms |
RG-FA; HDAC-1 inhibtors (Friedreich ataxia), RepliGen
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| Activity |
IC50 ~ 180000 nM
|
[3] | |||
| Compound Name |
N-(2-aminophenyl)nicotinamide
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Investigative | Compound Info | ||
| Synonyms |
N-(2-Amino-phenyl)-nicotinamide; 436089-31-5; N-(2-aminophenyl)nicotinamide; N-(2-aminophenyl)pyridine-3-carboxamide; CHEMBL236678; AC1LMN6K; SCHEMBL18086514; CTK4I7538; DTXSID50360661; CHEBI:125506; ZINC873967; BDBM50220259; 3463AE; AKOS000129725; RTR-042156; MCULE-7933541910; N-(2-aminophenyl)-3-pyridylcarboxamide; ZB014940; ACM436089315; ST086607; ASN 01337807; KB-298440; TR-042156; BC4148434; SR-01000329900; SR-01000329900-1; BRD-K20880473-001-04-6
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| Activity |
IC50 ~ 50000 nM
|
[4] | |||
| Compound Name |
N-(4-hydroxybiphenyl-3-yl)benzamide
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|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL269935; N-(4-hydroxybiphenyl-3-yl)benzamide; SCHEMBL5724398; BDBM50232005
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| Activity |
IC50 ~ 50000 nM
|
[5] | |||
| Compound Name |
N-(4-aminobiphenyl-3-yl)nicotinamide
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL255805; N-(4-aminobiphenyl-3-yl)nicotinamide; BDBM50232035
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| Activity |
IC50 ~ 50000 nM
|
[4] | |||
| Compound Name |
N-(4-aminobiphenyl-3-yl)benzamide
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Investigative | Compound Info | ||
| Synonyms |
N-(4-aminobiphenyl-3-yl)benzamide; CHEMBL271741; 3max; SCHEMBL16380794; BDBM50232053; N-(4-amino-biphenyl-3-yl)-benzamide
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| Activity |
IC50 ~ 50000 nM
|
[4] | |||
| Compound Name |
N-(2-amino-5-(thiophen-2-yl)phenyl)nicotinamide
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|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL256440; N-(2-amino-5-(thiophen-2-yl)phenyl)nicotinamide; SCHEMBL1066609
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| Activity |
IC50 ~ 50000 nM
|
[4] | |||
| Compound Name |
N-(2-aminophenyl)benzamide
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|
Investigative | Compound Info | ||
| Synonyms |
N-(2-aminophenyl)benzamide; 2'-AMINOBENZANILIDE; 721-47-1; CHEMBL405072; AC1LFSYX; AC1Q5NOK; ACMC-1AE0C; Oprea1_478192; MLS000084661; SCHEMBL407834; N-(2-amino-phenyl)-benzamide; AC1Q514U; Benzamide, N-(2-aminophenyl)-; CTK2H2825; DTXSID60353948; RFDVMOUXHKTCDO-UHFFFAOYSA-N; MolPort-001-783-352; ZINC225957; HMS2355D18; STL497474; BDBM50232046; AKOS000133162; MCULE-5545982713; NE17312; SMR000019009; TC-170926; KB-298435; ST51030142; EN300-31745; SR-01000389415; AE-641/00785046
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| Activity |
IC50 ~ 50000 nM
|
[4] | |||
| Compound Name |
PCI-34051
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Investigative | Compound Info | ||
| Synonyms |
PCI-34259; PCI-34260; PCI-40505; PCI-43744; PCI-45159; PCI-47634; PCI-48000; PCI-48001; PCI-48002; PCI-48003; PCI-48004; PCI-48006; PCI-48007; PCI-48008; PCI-48009; PCI-48010; PCI-48011; PCI-48012; PCI-48013; PCI-48018; PCI-48036; PCI-48039; HDAC 8 inhibitors (cancer/inflammation); HDAC 8 inhibitors (cancer/inflammation), Pharmacyclics
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| Activity |
IC50 ~ 100000 nM
|
[6] | |||
| Compound Name |
4-Phenylbutyrohydroxamic acid
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Investigative | Compound Info | ||
| Synonyms |
N-Hydroxy-4-phenylbutanamide; 32153-46-1; NSC131300; UNII-QX182FOM5S; QX182FOM5S; 4-phenylbutanehydroxamic acid; CHEMBL55895; 4-Phenylbutyrohydroxamic acid; Benzenebutanamide, N-hydroxy-; NSC 131300; AC1Q7DIW; AC1L5RDX; Phenylbutyrylhydroxamic Acid; AC1Q5QD1; N-Hydroxy-4-phenyl-butyramide; 4-Phenylbutyryl hydroxamic acid; SCHEMBL1350853; CTK4G8310; DTXSID60185943; MolPort-011-492-164; UPHXPXYRKPCXHK-UHFFFAOYSA-N; ZINC4962622; STL301752; BDBM50015142; AKOS009266186; MCULE-9765156954; NSC-131300; NE28489; BCB03_000829; EN300-68596
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| Activity |
IC50 = 140000 nM
|
[7] | |||
| Compound Name |
(1R,2R,3R)-2-(5-Chloro-2,2-dimethyl-3H-1,4-benzodioxin-7-yl)-N-hydroxy-3-phenylcyclopropane-1-carboxamide
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL3109981
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|
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| Activity |
IC50 ~ 50000 nM
|
[8] | |||
| Compound Name |
(1R,2R,3R)-N-Hydroxy-2-phenyl-3-[3-(trifluoromethyl)quinoxalin-6-yl]cyclopropane-1-carboxamide
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|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3110002
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|
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| Activity |
IC50 ~ 50000 nM
|
[8] | |||
| Compound Name |
(1R,2R,3R)-N-Hydroxy-2-(1-methylpyrazol-4-yl)-3-phenylcyclopropane-1-carboxamide
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|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3110023; SCHEMBL12499732; BDBM50446477
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| Activity |
IC50 ~ 50000 nM
|
[8] | |||
| Compound Name |
(1R,2R,3R)-N-Hydroxy-2-phenyl-3-(4-pyrimidin-2-ylphenyl)cyclopropane-1-carboxamide
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL3110014; SCHEMBL12498310; US9765054, Compound 50h; BDBM340828
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| Activity |
IC50 ~ 50000 nM
|
[8] | |||
| Compound Name |
(1R,2R,3R)-2-[4-(3,3-Difluoropyrrolidin-1-yl)phenyl]-N-hydroxy-3-phenylcyclopropane-1-carboxamide
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL3110011; SCHEMBL15768745; US9765054, Compound 56c; BDBM340902
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| Activity |
IC50 ~ 50000 nM
|
[8] | |||
| Compound Name |
N-[(2S)-3-(1H-Indol-3-yl)-1-oxo-1-[4-(propylaminocarbamoyl)anilino]propan-2-yl]-4-methoxybenzamide
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|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL4063938; BDBM50244779
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| Activity |
IC50 ~ 50000 nM
|
[9] | |||
| Compound Name |
(1R,2R,3S)-N-Hydroxy-2-(5-methyl-1,3-thiazol-2-yl)-3-phenylcyclopropane-1-carboxamide
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL3110024
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| Activity |
IC50 ~ 50000 nM
|
[8] | |||
| Compound Name |
2,2,3,3,4,4,5,5,6,6,7,7-Dodecafluorooctanedioic acid hydroxyamide pyren-1-ylamide
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL1934900; BDBM50361258; ZINC82158497; 2,2,3,3,4,4,5,5,6,6,7,7-dodecafluoro-N-hydroxy-N'-pyren-1-yloctanediamide
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| Activity |
Ki ~ 50000 nM
|
[10] | |||
| Compound Name |
(1R,2R,3R)-2-(2-Cyclopropyl-1,3-benzoxazol-5-yl)-N-hydroxy-3-phenylcyclopropane-1-carboxamide
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL3110000
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| Activity |
IC50 ~ 50000 nM
|
[8] | |||
| Compound Name |
Carbamic acid,N-[[4-[[(4-amino[1,1'-biphenyl]-3-yl)amino]carbonyl]phenyl]methyl]-,methyl ester
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL398420; Carbamic acid, N-[[4-[[(4-amino[1,1'-biphenyl]-3-yl)amino]carbonyl]phenyl]methyl]-, methyl ester; SCHEMBL4314772; BDBM50229192; ZINC29039034; Methyl {4-[(4-amino-3-biphenylyl)carbamoyl]benzyl}carbamate; [4-(4-amino-biphenyl-3-ylcarbamoyl)-benzyl]-carbamic acid methyl ester; methyl N-[[4-[(2-amino-5-phenylphenyl)carbamoyl]phenyl]methyl]carbamate; N-[[4-[[(4-Amino[1,1'-biphenyl]-3-yl)amino]carbonyl]phenyl]methyl]carbamic Acid Methyl Ester
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| Activity |
IC50 ~ 50000 nM
|
[1] | |||
| Compound Name |
2,2,3,3,4,4,5,5,6,6,7,7-Dodecafluorooctanedioic acid biphenyl-3-ylamide hydroxyamide
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL1934904; BDBM50361262; ZINC73224983; 2,2,3,3,4,4,5,5,6,6,7,7-dodecafluoro-N-hydroxy-N'-(3-phenylphenyl)octanediamide
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| Activity |
Ki ~ 50000 nM
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[10] | |||
| Compound Name |
N-(2-Chlorophenyl)-2,2,3,3,4,4,5,5,6,6,7,7-dodecafluoro-N'-hydroxyoctanediamide
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL4104197; BDBM50235702
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| Activity |
Ki ~ 50000 nM
|
[10] | |||
| Compound Name |
CID 57336568
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL1934905; BDBM50361263; ZINC73224984; 2,2,3,3,4,4,5,5,6,6,7,7-dodecafluoro-N-hydroxy-N'-naphthalen-2-yloctanediamide
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| Activity |
Ki ~ 50000 nM
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[10] | |||
| Compound Name |
CID 57521296
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL3109980; SCHEMBL15768774; BDBM50446474
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| Activity |
IC50 ~ 50000 nM
|
[8] | |||
| Compound Name |
Azumamide D
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL257973; BDBM50377382
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| Activity |
IC50 ~ 50000 nM
|
[11] | |||
| Compound Name |
2,2,3,3,4,4,5,5,6,6,7,7-Dodecafluorooctanedioic acid hydroxyamide (4-iodo-phenyl)amide
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL1934895; BDBM50361253; ZINC82158280; 2,2,3,3,4,4,5,5,6,6,7,7-dodecafluoro-N-hydroxy-N'-(4-iodophenyl)octanediamide
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| Activity |
Ki ~ 50000 nM
|
[10] | |||
| Compound Name |
2,2,3,3,4,4,5,5,6,6,7,7-Dodecafluoro-N-hydroxy-N'-(2-methylphenyl)octanediamide
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL4080874; BDBM50235706
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| Activity |
Ki ~ 50000 nM
|
[10] | |||
| Compound Name |
2,2,3,3,4,4,5,5,6,6,7,7-Dodecafluorooctanedioic Acid(4-Chlorophenyl)Amide Hydroxyamide
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL1934892; BDBM50361250; ZINC82158277; 2,2,3,3,4,4,5,5,6,6,7,7-Dodecafluorooctanedioic acid (4-chlorophenyl)amide hydroxyamide; N-(4-chlorophenyl)-2,2,3,3,4,4,5,5,6,6,7,7-dodecafluoro-N'-hydroxyoctanediamide
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| Activity |
Ki ~ 50000 nM
|
[10] | |||
| Compound Name |
(1R,2R,3R)-2-(3-Cyclopropylquinoxalin-6-yl)-N-hydroxy-3-phenylcyclopropane-1-carboxamide
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL3109977
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| Activity |
IC50 ~ 50000 nM
|
[8] | |||
| Compound Name |
(2R,3R)-N-Hydroxy-2,3-diphenylcyclopropane-1-carboxamide
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL3110005; SCHEMBL15768955; BDBM50446480
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| Activity |
IC50 ~ 50000 nM
|
[8] | |||
| Compound Name |
Benzyl (2S)-4-[5-[(2-amino-5-phenylphenyl)carbamoyl]pyridin-2-yl]-2-methylpiperazine-1-carboxylate
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL437029; SCHEMBL4534462; BDBM50374011
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| Activity |
IC50 ~ 50000 nM
|
[4] | |||
| Compound Name |
(1R,2R,3R)-N-Hydroxy-2-[4-(1,3-oxazol-4-yl)phenyl]-3-phenylcyclopropane-1-carboxamide
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL3109986
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| Activity |
IC50 ~ 50000 nM
|
[8] | |||
| Compound Name |
(1R,2R,3R)-N-Hydroxy-2-phenyl-3-(4-pyrimidin-5-ylphenyl)cyclopropane-1-carboxamide
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL3110013; SCHEMBL12499606; US9765054, Compound 50i; BDBM340824
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| Activity |
IC50 ~ 50000 nM
|
[8] | |||
| Compound Name |
(1R,2R,3R)-N-Hydroxy-2-phenyl-3-pyrazolo[1,5-a]pyridin-2-ylcyclopropane-1-carboxamide
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL3109997
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|
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| Activity |
IC50 ~ 50000 nM
|
[8] | |||
| Compound Name |
(1R,2R,3R)-N-Hydroxy-2-phenyl-3-[2-(trifluoromethyl)pyridin-4-yl]cyclopropane-1-carboxamide
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL3109994; SCHEMBL12498288; BDBM340871; US9765054, Compound 28G
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| Activity |
IC50 ~ 50000 nM
|
[8] | |||
| Compound Name |
N-Hydroxy-9H-fluorene-9-carboxamide
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL3110003; SCHEMBL4532733; BDBM50446482
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| Activity |
IC50 ~ 50000 nM
|
[8] | |||
| Compound Name |
(1R,2R,3R)-N-Hydroxy-2-phenyl-3-(4-pyridazin-3-ylphenyl)cyclopropane-1-carboxamide
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL3110012; SCHEMBL12498632; US9765054, Compound 50f; BDBM340879
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| Activity |
IC50 ~ 50000 nM
|
[8] | |||
| Compound Name |
N-[4-(Dimethylamino)phenyl]-2,2,3,3,4,4,5,5,6,6,7,7-dodecafluoro-N'-hydroxyoctanediamide
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL4066515; BDBM50235703
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| Activity |
Ki ~ 50000 nM
|
[10] | |||
| Compound Name |
Benzamide-type inhibitor, 4
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL235674; SCHEMBL1066960; BDBM19412; pyridin-3-ylmethyl N-[[4-[(2-amino-5-thiophen-2-ylphenyl)carbamoyl]phenyl]methyl]carbamate; pyridin-3-ylmethyl N-[(4-{[2-amino-5-(thiophen-2-yl)phenyl]carbamoyl}phenyl)methyl]carbamate
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| Activity |
IC50 ~ 50000 nM
|
[1] | |||
| Compound Name |
(1R,2R,3R)-2-[4-(3,3-Dimethylazetidin-1-yl)phenyl]-N-hydroxy-3-phenylcyclopropane-1-carboxamide
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL3110009; SCHEMBL12499743; US9765054, Compound 56d; BDBM340900
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| Activity |
IC50 ~ 50000 nM
|
[8] | |||
| Compound Name |
2,2,3,3,4,4,5,5,6,6,7,7-Dodecafluorooctanedioic acid biphenyl-2-ylamide hydroxyamide
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL1934906; BDBM50361264; ZINC73224985; 2,2,3,3,4,4,5,5,6,6,7,7-dodecafluoro-N-hydroxy-N'-(2-phenylphenyl)octanediamide
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| Activity |
Ki ~ 50000 nM
|
[10] | |||
| Compound Name |
N-(3-Chlorophenyl)-2,2,3,3,4,4,5,5,6,6,7,7-dodecafluoro-N'-hydroxyoctanediamide
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL4093113; BDBM50235705
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| Activity |
Ki ~ 50000 nM
|
[10] | |||
| Compound Name |
5-[[6-Oxo-4-(4-phenylphenyl)-1H-pyrimidin-2-yl]sulfanyl]pentanehydroxamic acid
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Investigative | Compound Info | ||
| Synonyms |
MC1742; CHEMBL3426803; SCHEMBL18495059; BDBM50087845; AKOS027470271; ZINC140782936; MC 1742; MC-1742
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| Activity |
IC50 ~ 50000 nM
|
[12] | |||
| Compound Name |
3beta-[4-(2-Cyclopropyl-5-oxazolyl)phenyl]-2alpha-phenylcyclopropane-1alpha-carbohydroxamic acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3109985; SCHEMBL12498656; BDBM50446470; (1R,2R,3R)-2-[4-(2-cyclopropyl-1,3-oxazol-5-yl)phenyl]-N-hydroxy-3-phenylcyclopropane-1-carboxamide
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 50000 nM
|
[8] | |||
| Compound Name |
3beta-(2-Cyclopropyl-4-pyridyl)-2alpha-phenylcyclopropane-1alpha-carbohydroxamic acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3109993; SCHEMBL12498652; BDBM50446476; (1R,2R,3R)-2-(2-cyclopropylpyridin-4-yl)-N-hydroxy-3-phenylcyclopropane-1-carboxamide
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 50000 nM
|
[8] | |||
| Compound Name |
2,2,3,3,4,4,5,5,6,6,7,7-Dodecafluorooctanedioic Acid(4-Cyanophenyl)Amide Hydroxyamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL1934894; BDBM50361252; ZINC82158279; 2,2,3,3,4,4,5,5,6,6,7,7-Dodecafluorooctanedioic acid (4-cyanophenyl)amide hydroxyamide; N-(4-cyanophenyl)-2,2,3,3,4,4,5,5,6,6,7,7-dodecafluoro-N'-hydroxyoctanediamide
Click to Show/Hide
|
||||
| Activity |
Ki ~ 50000 nM
|
[10] | |||
| Compound Name |
CID 57336565
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL1934902; BDBM50361260; ZINC82164608; 2,2,3,3,4,4,5,5,6,6,7,7-dodecafluoro-N-hydroxy-N'-[4-(3-phenyltriazol-4-yl)phenyl]octanediamide
Click to Show/Hide
|
||||
| Activity |
Ki ~ 50000 nM
|
[10] | |||
| Compound Name |
(1R,2R,3R)-N-Hydroxy-2-phenyl-3-quinoxalin-6-ylcyclopropane-1-carboxamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3110001; BDBM50446475
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 50000 nM
|
[8] | |||
| Compound Name |
N-Hydroxy-2-(1-methylpyrrole-2-carbonyl)-3,4-dihydro-1H-pyrrolo[1,2-a]pyrazine-7-carboxamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3353053; SCHEMBL12210526; BDBM50036285
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 50000 nM
|
[13] | |||
| Compound Name |
(1S,2S)-N-Hydroxy-2-phenylcyclopropane-1-carboxamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3110008
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 50000 nM
|
[8] | |||
| Compound Name |
(1R,2R,3R)-2-(6-Cyclopropylpyridazin-4-yl)-N-hydroxy-3-phenylcyclopropane-1-carboxamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3109992; SCHEMBL12499761
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 50000 nM
|
[8] | |||
| Compound Name |
2,2,3,3,4,4,5,5,6,6,7,7-Dodecafluorooctanedioic Acid(3-Ethylphenyl)Amide Hydroxyamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL1934898; BDBM50361256; ZINC82158495; 2,2,3,3,4,4,5,5,6,6,7,7-Dodecafluorooctanedioic acid (3-ethylphenyl)amide hydroxyamide; N-(3-ethylphenyl)-2,2,3,3,4,4,5,5,6,6,7,7-dodecafluoro-N'-hydroxyoctanediamide
Click to Show/Hide
|
||||
| Activity |
Ki ~ 50000 nM
|
[10] | |||
| Compound Name |
(1R,2R,3R)-2-(2-Cyclopropylquinoxalin-6-yl)-N-hydroxy-3-phenylcyclopropane-1-carboxamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3109978
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 50000 nM
|
[8] | |||
| Compound Name |
(1R,2R,3R)-N-Hydroxy-2-[4-(5-methyl-1H-imidazol-2-yl)phenyl]-3-phenylcyclopropane-1-carboxamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3110018; SCHEMBL12498722; US9765054, Compound 50l; BDBM340916
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 50000 nM
|
[8] | |||
| Compound Name |
(1R,2R,3R)-N-Hydroxy-2-[3-(1,3-oxazol-5-yl)phenyl]-3-phenylcyclopropane-1-carboxamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3109987; SCHEMBL15769094; BDBM340861; US9765054, Compound 41A
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 50000 nM
|
[8] | |||
| Compound Name |
3beta-[4-(1-Methyl-1H-imidazole-2-yl)phenyl]-2alpha-phenylcyclopropane-1alpha-carbohydroxamic acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3110017; SCHEMBL12498360; US9765054, Compound 60; BDBM340893
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 50000 nM
|
[8] | |||
| Compound Name |
(1R,2R,3R)-N-Hydroxy-2-[4-(1,3-oxazol-2-yl)phenyl]-3-phenylcyclopropane-1-carboxamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3110020; SCHEMBL15768742; US9765054, Compound 58; BDBM340885
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 50000 nM
|
[8] | |||
| Compound Name |
(1R,2R,3R)-2-(2-Cyclopropylpyrimidin-5-yl)-N-hydroxy-3-phenylcyclopropane-1-carboxamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3109991; SCHEMBL12498081
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 50000 nM
|
[8] | |||
| Compound Name |
2-(2,2-Dimethylpropanoyl)-N-hydroxy-1,3-dihydroisoindole-5-carboxamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL2431907; SCHEMBL1262950; BDBM50440909
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 50000 nM
|
[14] | |||
| Compound Name |
(1R,2R,3R)-2-(2,3-Dihydro-1,4-benzodioxin-6-yl)-N-hydroxy-3-phenylcyclopropane-1-carboxamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3109979; SCHEMBL15768688
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 50000 nM
|
[8] | |||
| Compound Name |
(1R,2R,3S)-N-Hydroxy-2-(2-methyl-1,3-thiazol-5-yl)-3-phenylcyclopropane-1-carboxamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3109988; SCHEMBL12497906
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 50000 nM
|
[8] | |||
| Compound Name |
(1R,2R,3R)-N-Hydroxy-2-phenyl-3-[6-(trifluoromethyl)pyridin-3-yl]cyclopropane-1-carboxamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3108793; SCHEMBL15768899; US9765054, Compound 28f; BDBM340865
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 50000 nM
|
[8] | |||
| Compound Name |
2,2,3,3,4,4,5,5,6,6,7,7-Dodecafluoro-N-hydroxy-N'-[3-(1-phenyltriazol-4-yl)phenyl]octanediamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL4066343; BDBM50235704
Click to Show/Hide
|
||||
| Activity |
Ki ~ 50000 nM
|
[10] | |||
| Compound Name |
N-Hydroxy-2-(1-methylpyrrole-2-carbonyl)-1,3,4,5-tetrahydro-2-benzazepine-7-carboxamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL2431912; SCHEMBL1264164; BDBM50440908
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 50000 nM
|
[14] | |||
| Compound Name |
2,2,3,3,4,4,5,5,6,6,7,7-Dodecafluorooctanedioic acid (4-acetylaminophenyl)-amide hydroxyamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL1934893; BDBM50361251; ZINC82158278; N-(4-acetamidophenyl)-2,2,3,3,4,4,5,5,6,6,7,7-dodecafluoro-N'-hydroxyoctanediamide
Click to Show/Hide
|
||||
| Activity |
Ki ~ 50000 nM
|
[10] | |||
| Compound Name |
CID 76310313
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3109984; SCHEMBL15769130; BDBM50446471; (1R,2R,3R)-N-hydroxy-2-[4-(2-methyl-1,3-oxazol-5-yl)phenyl]-3-phenylcyclopropane-1-carboxamide
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 50000 nM
|
[8] | |||
| Compound Name |
(2R,3S)-N-Hydroxy-2,3-diphenylcyclopropane-1-carboxamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3110006
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 50000 nM
|
[8] | |||
| Compound Name |
2,2,3,3,4,4,5,5,6,6,7,7-Dodecakis(Fluoranyl)-~{n}-Oxidanyl-~{n}'-Phenyl-Octanediamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL1934890; 2,2,3,3,4,4,5,5,6,6,7,7-Dodecafluorooctanedioic acid hydroxyamide phenyl-amide; SCHEMBL12471334; DTXSID70718943; BDBM50361248; LU-210; ZINC40163586; 2,2,3,3,4,4,5,5,6,6,7,7-dodecafluoro-N'-hydroxy-N-phenyloctanediamide; 2,2,3,3,4,4,5,5,6,6,7,7-Dodecafluoro-N~1~-hydroxy-N~8~-phenyloctanediamide
Click to Show/Hide
|
||||
| Activity |
Ki ~ 50000 nM
|
[10] | |||
| Compound Name |
2,2,3,3,4,4,5,5,6,6,7,7-Dodecafluorooctanedioic acid hydroxyamide phenan-thren-9-ylamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL1934908; BDBM50361266; ZINC73224987; 2,2,3,3,4,4,5,5,6,6,7,7-dodecafluoro-N-hydroxy-N'-phenanthren-9-yloctanediamide
Click to Show/Hide
|
||||
| Activity |
Ki ~ 50000 nM
|
[10] | |||
| Compound Name |
2,2,3,3,4,4,5,5,6,6,7,7-Dodecafluoro-N-(4-fluorophenyl)-N'-hydroxyoctanediamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL4079958; BDBM50235708
Click to Show/Hide
|
||||
| Activity |
Ki ~ 50000 nM
|
[10] | |||
| Compound Name |
(1R,2R,3R)-N-Hydroxy-2-(2-methyl-1,3-benzothiazol-5-yl)-3-phenylcyclopropane-1-carboxamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3109999
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 50000 nM
|
[8] | |||
| Compound Name |
Ethyl 4-((2-amino-5-(thiophen-2-yl)phenyl)carbamoyl)benzylcarbamate
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL399494; SCHEMBL8101991; BDBM50229197; ethyl N-[[4-[(2-amino-5-thiophen-2-ylphenyl)carbamoyl]phenyl]methyl]carbamate
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 50000 nM
|
[1] | |||
| Compound Name |
2,2,3,3,4,4,5,5,6,6,7,7-Dodecafluorooctanedioic acid hydroxyamide (4-phenylthiazol-2-yl)amide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL1934901; BDBM50361259; ZINC73219822; 2,2,3,3,4,4,5,5,6,6,7,7-dodecafluoro-N-hydroxy-N'-(4-phenyl-1,3-thiazol-2-yl)octanediamide
Click to Show/Hide
|
||||
| Activity |
Ki ~ 50000 nM
|
[10] | |||
| Compound Name |
2,2,3,3,4,4,5,5,6,6,7,7-Dodecafluoro-N-hydroxy-N'-(4-methoxyphenyl)octanediamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL4095542; BDBM50235707
Click to Show/Hide
|
||||
| Activity |
Ki ~ 50000 nM
|
[10] | |||
| Compound Name |
3beta-Cyclopentyl-2alpha-phenylcyclopropane-1alpha-carbohydroxamic acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3110022; SCHEMBL12499002; BDBM340851; US9765054, Compound 25A
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 50000 nM
|
[8] | |||
| Compound Name |
Methyl 4-((2-amino-5-(thiophen-2-yl)phenyl)carbamoyl)benzylcarbamate
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL400721; SCHEMBL4323563; BDBM50229193; ZINC29039255; AKOS016360308; DA-16374; FT-0749974; methyl N-[[4-[(2-amino-5-thiophen-2-ylphenyl)carbamoyl]phenyl]methyl]carbamate
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 50000 nM
|
[1] | |||
| Compound Name |
(1R,2R,3R)-N-Hydroxy-2-phenyl-3-pyrimidin-5-ylcyclopropane-1-carboxamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3109989; SCHEMBL12498239; BDBM340850; US9765054, Compound 25C
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 50000 nM
|
[8] | |||
| Compound Name |
CID 57336570
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL1934907; BDBM50361265; ZINC73224986; N-anthracen-2-yl-2,2,3,3,4,4,5,5,6,6,7,7-dodecafluoro-N'-hydroxyoctanediamide
Click to Show/Hide
|
||||
| Activity |
Ki ~ 50000 nM
|
[10] | |||
| Compound Name |
3beta-(Imidazo[1,2-a]pyridine-2-yl)-2alpha-phenylcyclopropane-1alpha-carbohydroxamic acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3109996
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 50000 nM
|
[8] | |||
| Compound Name |
2,2,3,3,4,4,5,5,6,6,7,7-Dodecafluorooctanedioic acid biphenyl-4-ylamide hydroxyamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL1934897; BDBM50361255; ZINC82158320; 2,2,3,3,4,4,5,5,6,6,7,7-dodecafluoro-N-hydroxy-N'-(4-phenylphenyl)octanediamide
Click to Show/Hide
|
||||
| Activity |
Ki ~ 50000 nM
|
[10] | |||
| Compound Name |
(1R,2R,3R)-N-Hydroxy-2-[4-(2-oxa-6-azaspiro[3.3]heptan-6-yl)phenyl]-3-phenylcyclopropane-1-carboxamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3110010; SCHEMBL12498482; US9765054, Compound 56e; BDBM340903
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 50000 nM
|
[8] | |||
| Compound Name |
N-Hydroxy-2-(1-methylpyrrole-2-carbonyl)-3,4-dihydro-1H-isoquinoline-6-carboxamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
MPI-5a; MPI_5a; CHEMBL2431901; SCHEMBL722256; SYN1218; BCP29593; EX-A1852; BDBM50440907; ZINC68248700; DB-092801; HY-113957; CS-0064770; MPI 5a;MPI5a;HDAC6 Inhibitor;Histone Deacetylase 6
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 50000 nM
|
[13] | |||
| Compound Name |
(1R,2R,3R)-N-Hydroxy-2-phenyl-3-[5-(trifluoromethyl)pyridin-3-yl]cyclopropane-1-carboxamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3109995; SCHEMBL12498519; US9765054, Compound 68; BDBM340864
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 50000 nM
|
[8] | |||
| Compound Name |
2alpha-Phenylcyclopropane-1alpha-carbohydroxamic acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3110007
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 50000 nM
|
[8] | |||
| Compound Name |
N-(2-Amino-5-(thiophen-2-yl)phenyl)-6-(2-oxo-1-oxa-3,8-diazaspiro[4.5]decan-8-yl)nicotinamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
MRLB-223; CHEMBL3286732; SCHEMBL1639102; BDBM50016941
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 50000 nM
|
[15] | |||
| Compound Name |
N-Hydroxy-2-[(1-methyl-1H-pyrrol-2-yl)carbonyl]isoindoline-5-carboxamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL2431906; SCHEMBL1263733; BDBM50440910; N-hydroxy-2-(1-methylpyrrole-2-carbonyl)-1,3-dihydroisoindole-5-carboxamide
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 50000 nM
|
[14] | |||
| Compound Name |
Diethyl(4-(2-amino-5-(thiophen-2-yl)phenylcarbamoyl)benzylamino)methylphosphonate
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL470225; SCHEMBL2208777; BDBM50278515; N-(2-amino-5-thiophen-2-ylphenyl)-4-[(diethoxyphosphorylmethylamino)methyl]benzamide; diethyl [({[4-({[2-amino-5-(2-thienyl)phenyl]amino) carbonyl}phenyl]methyl}amino)methyl]phosphonate
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 50000 nM
|
[16] | |||
| Compound Name |
(1R,2R,3R)-2-[3-Fluoro-4-(5-methyl-1H-imidazol-2-yl)phenyl]-N-hydroxy-3-phenylcyclopropane-1-carboxamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3110019; SCHEMBL12498928
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 50000 nM
|
[8] | |||
| Compound Name |
2-(2,2-Dimethylpropanoyl)-N-hydroxy-3,4-dihydro-1H-isoquinoline-6-carboxamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL2431902; SCHEMBL1263305; BDBM50440911
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 50000 nM
|
[14] | |||
| Compound Name |
3beta-[1-Oxo-2-(2,2,2-trifluoroethyl)isoindoline-5-yl]-2alpha-phenylcyclopropane-1alpha-carbohydroxamic acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3109983; SCHEMBL12499015; BDBM50446473
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 50000 nM
|
[8] | |||
| Compound Name |
2,2,3,3,4,4,5,5,6,6,7,7-Dodecafluorooctanedioic acid (3,4-dimethylphenyl)-amide hydroxyamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL1934896; BDBM50361254; ZINC82158281; N-(3,4-dimethylphenyl)-2,2,3,3,4,4,5,5,6,6,7,7-dodecafluoro-N'-hydroxyoctanediamide
Click to Show/Hide
|
||||
| Activity |
Ki ~ 50000 nM
|
[10] | |||
| Compound Name |
N-Hydroxy-4-(((2-phenoxyethyl)(5-p-tolylthiazol-2-yl)amino)methyl)benzamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL586040; BDBM50302946
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 50000 nM
|
[17] | |||
| Compound Name |
(1R,2R,3R)-2-(8-Chloro-1,2,3,4-tetrahydroquinolin-6-yl)-N-hydroxy-3-phenylcyclopropane-1-carboxamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3109982; SCHEMBL12498068
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 50000 nM
|
[8] | |||
| Compound Name |
N-(2-Amino-5-thiophen-2-ylphenyl)benzamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL271949; SCHEMBL1067101; BDBM50374007
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 50000 nM
|
[4] | |||
| Compound Name |
2,2,3,3,4,4,5,5,6,6,7,7-Dodecafluorooctanedioic acid hydroxyamide naph-thalen-1-ylamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL1934903; BDBM50361261; ZINC73224745; 2,2,3,3,4,4,5,5,6,6,7,7-dodecafluoro-N-hydroxy-N'-naphthalen-1-yloctanediamide
Click to Show/Hide
|
||||
| Activity |
Ki ~ 50000 nM
|
[10] | |||
| Compound Name |
2,2,3,3,4,4,5,5,6,6,7,7-Dodecafluoro-N,N'-diphenyloctanediamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL1934910; BDBM50361268
Click to Show/Hide
|
||||
| Activity |
Ki ~ 50000 nM
|
[10] | |||
| Compound Name |
N-Hydroxy-4-(((2-(p-tolyloxy)ethyl)(5-p-tolylthiazol-2-yl)amino)methyl)benzamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL584273; BDBM50302945
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 50000 nM
|
[17] | |||
| Compound Name |
Azumamide A
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL255714; BDBM50377385
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 50000 nM
|
[11] | |||
| Compound Name |
(1r,2r,3r)-2-[4-(1,3-Oxazol-5-Yl)phenyl]-N-Oxidanyl-3-Phenyl-Cyclopropane-1-Carboxamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3110021; SCHEMBL12498601; BDBM50446472; Q27461940; (1r,2r,3r)-N-hydroxy-2-(4-(oxazol-5-yl)phenyl)-3-phenylcyclopropane-1-carboxamide; (1R,2R,3R)-N-hydroxy-2-[4-(1,3-oxazol-5-yl)phenyl]-3-phenylcyclopropane-1-carboxamide; (1R,2R,3R)-N-hydroxy-2-[4-(1,3-oxazol-5-yl)phenyl]-3-phenylcyclopropanecarboxamide; 3beta-[4-(5-Oxazolyl)phenyl]-2alpha-phenylcyclopropane-1alpha-carbohydroxamic acid
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 50000 nM
|
[8] | |||
| Compound Name |
2,2,3,3,4,4,5,5,6,6,7,7-Dodecafluoro-N-hydroxy-N'-(3-methylphenyl)octanediamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL4098910; BDBM50235701
Click to Show/Hide
|
||||
| Activity |
Ki ~ 50000 nM
|
[10] | |||
| Compound Name |
(1R,2R,3R)-N-Hydroxy-2-phenyl-3-pyridazin-4-ylcyclopropane-1-carboxamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3109990; SCHEMBL15769082; BDBM340859; US9765054, Compound 28A
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 50000 nM
|
[8] | |||
| Compound Name |
Thailandepsin A
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL1836142; BDBM50354088
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 50000 nM
|
[2] | |||
| Compound Name |
(1R,2S,3R)-N-Hydroxy-2-phenyl-3-[6-(trifluoromethyl)imidazo[2,1-b][1,3]thiazol-2-yl]cyclopropane-1-carboxamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3109998
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 50000 nM
|
[8] | |||
| Compound Name |
2,2,3,3,4,4,5,5,6,6,7,7-Dodecafluorooctanedioic acid hydroxyamide 4-methyl-phenylamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL1934891; BDBM50361249; ZINC73240866; 2,2,3,3,4,4,5,5,6,6,7,7-dodecafluoro-N-hydroxy-N'-(4-methylphenyl)octanediamide
Click to Show/Hide
|
||||
| Activity |
Ki ~ 50000 nM
|
[10] | |||
| Compound Name |
(1r,2r,3r)-2-[4-(5-Fluoranylpyrimidin-2-Yl)phenyl]-N-Oxidanyl-3-Phenyl-Cyclopropane-1-Carboxamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3110015; SCHEMBL12499741; BDBM50446479; Q27457014; (1R,2R,3R)-2-[4-(5-fluoropyrimidin-2-yl)phenyl]-N-hydroxy-3-phenylcyclopropanecarboxamide; (1R,2R,3R)-2-[4-(5-fluoropyrimidin-2-yl)phenyl]-N-hydroxy-3-phenylcyclopropane-1-carboxamide; 3beta-[4-(5-Fluoro-2-pyrimidinyl)phenyl]-2alpha-phenylcyclopropane-1alpha-carbohydroxamic acid
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 50000 nM
|
[8] | |||
| Compound Name |
2,2,3,3,4,4,5,5,6,6,7,7-Dodecafluorooctanedioic acid anthracen-1-ylamide hydroxyamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL1934909; BDBM50361267; ZINC73220718; N-anthracen-1-yl-2,2,3,3,4,4,5,5,6,6,7,7-dodecafluoro-N'-hydroxyoctanediamide
Click to Show/Hide
|
||||
| Activity |
Ki ~ 50000 nM
|
[10] | |||
| Compound Name |
(1R,2R,3R)-2-[3-(5-Fluoropyrimidin-2-yl)phenyl]-N-hydroxy-3-phenylcyclopropane-1-carboxamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3110016; SCHEMBL12499288; BDBM50446478
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 50000 nM
|
[8] | |||
| Compound Name |
(E)-3-[5-[[Benzyl(2-phenoxyethyl)amino]methyl]furan-2-yl]-N-hydroxyprop-2-enamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL2413293; BDBM50492827
Click to Show/Hide
|
||||
| Activity |
IC50 = 50560 nM
|
[18] | |||
| Compound Name |
(E)-5-(4-(Dimethylamino)styryl)-N-hydroxyfuran-2-carboxamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL472346; BDBM50244921
Click to Show/Hide
|
||||
| Activity |
IC50 = 50580 nM
|
[19] | |||
| Compound Name |
(E)-3-[5-[[2-(1,3-Benzodioxol-5-yl)ethyl-[2-(4-methylphenoxy)ethyl]amino]methyl]furan-2-yl]-N-hydroxyprop-2-enamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL2413289; BDBM50492823
Click to Show/Hide
|
||||
| Activity |
IC50 = 52450 nM
|
[18] | |||
| Compound Name |
N-[4-[2-[(4-Methyl-6-oxo-1H-pyrimidin-2-yl)oxy]acetyl]phenyl]acetamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL1800246; BDBM50348393
Click to Show/Hide
|
||||
| Activity |
IC50 = 54200 nM
|
[20] | |||
| Compound Name |
5-[1-[(4-Anilinophenyl)methyl]pyrazol-3-yl]-N-hydroxypentanamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3335299; BDBM50026429
Click to Show/Hide
|
||||
| Activity |
IC50 = 56300 nM
|
[21] | |||
| Compound Name |
(E)-N-Hydroxy-5-(4-hydroxystyryl)furan-2-carboxamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL512179; BDBM50244873
Click to Show/Hide
|
||||
| Activity |
IC50 = 57060 nM
|
[19] | |||
| Compound Name |
Thailandepsin B
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL1836145; BDBM50354084
Click to Show/Hide
|
||||
| Activity |
IC50 = 57440 nM
|
[22] | |||
| Compound Name |
(1S,5S,6R,9S,15E,20R)-5-Hydroxy-6-(2-methylpropyl)-20-(2-methylsulfanylethyl)-2-oxa-11,12-dithia-7,19,22-triazabicyclo[7.7.6]docos-15-ene-3,8,18,21-tetrone
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3218563; BDBM50496768
Click to Show/Hide
|
||||
| Activity |
IC50 = 58880 nM
|
[22] | |||
| Compound Name |
(E)-3-[4-[3-(1-Adamantyl)-4-hydroxyphenyl]phenyl]-N-hydroxyprop-2-enamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3235463; SCHEMBL3295457; SCHEMBL3295460; BDBM50005744; E-3-[3'-(1-adamantyl)-4'-hydroxy-biphenyl-4-yl]-N-hydroxy-acrylamide
Click to Show/Hide
|
||||
| Activity |
IC50 = 61400 nM
|
[23] | |||
| Compound Name |
(1S,14S,17R,23S)-23-Propan-2-yl-7,8-dithia-15,21,24,26-tetrazatricyclo[12.11.2.017,21]heptacosane-16,22,25,27-tetrone
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3310510; BDBM50048862
Click to Show/Hide
|
||||
| Activity |
IC50 = 63000 nM
|
[24] | |||
| Compound Name |
(2R)-2-[(1-Hydroxy-6-sulfanylidenepyridine-2-carbonyl)amino]-2-phenylacetic acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3260858; BDBM50014161
Click to Show/Hide
|
||||
| Activity |
IC50 = 64000 nM
|
[25] | |||
| Compound Name |
2-[5-(3-Nitrophenyl)furfuryl]-1,2,3,4-tetrahydroisoquinoline-7-carbohydroximic acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3338404; BDBM50027664
Click to Show/Hide
|
||||
| Activity |
IC50 = 67800 nM
|
[26] | |||
| Compound Name |
(E)-3-[5-[[Benzyl-[2-(4-methylphenoxy)ethyl]amino]methyl]furan-2-yl]-N-hydroxyprop-2-enamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL2413294; BDBM50492836
Click to Show/Hide
|
||||
| Activity |
IC50 = 68110 nM
|
[18] | |||
| Compound Name |
1-Hydroxy-6-sulfanylidene-1,6-dihydropyridine-2-carboxylic acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
1-Hydroxy-6-thioxo-1,6-dihydropyridine-2-carboxylic acid; CHEMBL3617543; 2-Pyridinecarboxylic acid, 1,6-dihydro-1-hydroxy-6-thioxo; 1-hydroxy-6-sulfanylidenepyridine-2-carboxylic acid; SCHEMBL2787843; SCHEMBL13024190; BDBM50119287; MFCD20646150; AKOS030627735; ZINC145002146; AS-71624; SC-97473; 2-Pyridinecarboxylic acid, 1,6-dihydro-1-hydroxy-6; Z2070538118
Click to Show/Hide
|
||||
| Activity |
IC50 = 71000 nM
|
[25] | |||
| Compound Name |
1-(2,4-Dihydroxy-5-propan-2-ylphenyl)-N-[7-(hydroxyamino)-7-oxoheptyl]-5-[4-(morpholin-4-ylmethyl)phenyl]triazole-4-carboxamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3235118; BDBM50008222
Click to Show/Hide
|
||||
| Activity |
IC50 = 71500 nM
|
[27] | |||
| Compound Name |
(E)-N-Hydroxy-5-(2-hydroxystyryl)furan-2-carboxamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL472532; BDBM50244874
Click to Show/Hide
|
||||
| Activity |
IC50 = 74240 nM
|
[19] | |||
| Compound Name |
5-(2,4-Dihydroxy-5-propan-2-ylbenzoyl)-N-[7-(hydroxyamino)-7-oxoheptyl]-6,7-dihydro-4H-[1,2]oxazolo[4,5-c]pyridine-3-carboxamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3233755; BDBM50007730
Click to Show/Hide
|
||||
| Activity |
IC50 = 75900 nM
|
[28] | |||
| Compound Name |
N-Hydroxy-5-[1-[(3-phenylphenyl)methyl]pyrazol-3-yl]pentanamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3335283; BDBM50026450
Click to Show/Hide
|
||||
| Activity |
IC50 = 81500 nM
|
[21] | |||
| Compound Name |
N-Hydroxy-5-[1-[(4-phenylphenyl)methyl]pyrazol-3-yl]pentanamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3335300; BDBM50026431
Click to Show/Hide
|
||||
| Activity |
IC50 = 83100 nM
|
[21] | |||
| Compound Name |
(E)-5-(2-(Benzo[d][1,3]dioxol-5-yl)vinyl)-N-hydroxyfuran-2-carboxamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL472345; BDBM50244918
Click to Show/Hide
|
||||
| Activity |
IC50 = 85600 nM
|
[19] | |||
| Compound Name |
N-Hydroxy-5-[1-[(4-indol-1-ylphenyl)methyl]pyrazol-3-yl]pentanamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3335298; BDBM50026433
Click to Show/Hide
|
||||
| Activity |
IC50 = 86400 nM
|
[21] | |||
| Compound Name |
N-Hydroxy-E-3-(4''-methoxybiphenyl-4-yl)-acrylamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL561209; SCHEMBL3292536; SCHEMBL3292542; BDBM50293361; (E)-N-hydroxy-3-[4-(4-methoxyphenyl)phenyl]prop-2-enamide
Click to Show/Hide
|
||||
| Activity |
IC50 = 99400 nM
|
[23] | |||
| Compound Name |
2-[(4-Methyl-6-oxo-1H-pyrimidin-2-yl)sulfanyl]-N-(6-phenylhexyl)acetamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL1800385; BDBM50348387
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[20] | |||
| Compound Name |
Pimelic Diphenylamide 106
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
TC-H 106; N1-(2-aminophenyl)-N7-(4-methylphenyl)-heptanediamide; N'-(2-aminophenyl)-N-(4-methylphenyl)heptanediamide; RGFA-8;TC-H 106;Histone Deacetylase Inhibitor VII; RGFA-8; SCHEMBL1065609; CHEMBL3940985; DTXSID10581754; EX-A916; TC-H106; BDBM207628; HMS3648I10; BCP16854; US9265734, RGFA8; 1900AH; MFCD17010287; s6738; ZINC34997445; AKOS024458065; CCG-208665; CS-5229; TC-H 106;Pimelic Diphenylamide 106; AK222718; AS-56015; HY-19348; FT-0700415; n1-(2-aminophenyl)-n7-p-tolylheptanediamide; EC-000.2470; Pimelic Diphenylamide 106, >=98% (HPLC); SR-01000946373; SR-01000946373-1; N-(4-Methylphenyl)-N'-(2-aminophenyl)heptanediamide; N1-(2-Aminophenyl)-N7-(4-methylphenyl)heptanediamide; Q27165947; N~1~-(2-Aminophenyl)-N~7~-(4-methylphenyl)heptanediamide
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[29] | |||
| Compound Name |
N-[(2S)-1-[[6-(2-Amino-4-fluoroanilino)-6-oxohexyl]amino]-3-(1H-indol-3-yl)-1-oxopropan-2-yl]-4-methoxybenzamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL4102988; BDBM50242039
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[30] | |||
| Compound Name |
2-{[2-(4-Tert-butylphenyl)-2-oxoethyl]sulfanyl}-6-methyl-3,4-dihydropyrimidin-4-one
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL1800374; ZINC9143521; BDBM50348375; AKOS034466005; MCULE-3132766776; Z56923981
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[20] | |||
| Compound Name |
(2E,4E)-5-[4-[3-(1-Adamantyl)-4-methoxyphenyl]phenyl]-N-hydroxypenta-2,4-dienamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3235787; BDBM50005732
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[23] | |||
| Compound Name |
N-[4-[2-(4-Methylpyrimidin-2-yl)sulfanylacetyl]phenyl]acetamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL1800242; BDBM50348389
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[20] | |||
| Compound Name |
N-[4-[(4-Methyl-6-oxo-1H-pyrimidin-2-yl)sulfanylmethyl]phenyl]acetamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL1800248; SCHEMBL17382802; BDBM50348395
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[20] | |||
| Compound Name |
N-Hydroxy-3-[1-(2-phenylethyl)triazol-4-yl]benzamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL2178344; NCC-32; BDBM50399674
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[6] | |||
| Compound Name |
(1R,14S,17R,23S)-23-Benzyl-7,8-dithia-15,21,24,26-tetrazatricyclo[12.11.2.017,21]heptacosane-16,22,25,27-tetrone
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3310508; BDBM50048860
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[24] | |||
| Compound Name |
N-[4-[2-[(4-Methyl-6-oxo-1H-pyridin-2-yl)oxy]acetyl]phenyl]acetamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL1800247; BDBM50348394
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[20] | |||
| Compound Name |
(E)-N-Hydroxy-3-[4-(trifluoromethyl)phenyl]acrylamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3394285; SCHEMBL12425758; BDBM50140176; (E)-3-[4-(trifluoromethyl)phenyl]prop-2-enehydroxamic acid
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[31] | |||
| Compound Name |
2-[(4-Methyl-6-oxo-1H-pyrimidin-2-yl)sulfanyl]-N-(4-phenylbutyl)acetamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL1800384; BDBM50348385
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[20] | |||
| Compound Name |
(1R,14S,17R,23S)-23-Propan-2-yl-7,8-dithia-15,21,24,26-tetrazatricyclo[12.11.2.017,21]heptacosane-16,22,25,27-tetrone
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3310507; BDBM50048859
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[24] | |||
| Compound Name |
(1S,12R,15S,18R)-15-Propan-2-yl-24,25-dithia-3,14,17,31-tetrazatetracyclo[16.12.2.03,12.05,10]dotriaconta-5,7,9-triene-2,13,16,32-tetrone
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3310511; BDBM50048863
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[24] | |||
| Compound Name |
1-((4-Hydroxy-6-methylpyrimidin-2-yl)thio)propan-2-one
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL1800381; BDBM50348382; STL267143; AKOS008981021; AKOS016354209; MCULE-9373031239; 6-methyl-2-[(2-oxopropyl)sulfanyl]pyrimidin-4(3H)-one; 1-[(4-Oxo-6-methyl-3,4-dihydropyrimidine-2-yl)thio]-2-propanone
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[20] | |||
| Compound Name |
N-[4-[2-(3-Hydroxyphenyl)sulfanylacetyl]phenyl]acetamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL1800245; BDBM50348392
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[20] | |||
| Compound Name |
N-[4-[1-Hydroxy-2-[(4-methyl-6-oxo-1H-pyrimidin-2-yl)sulfanyl]ethyl]phenyl]acetamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL1800249; BDBM50348396
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[20] | |||
| Compound Name |
Chembl4202863
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
BDBM50458324
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[32] | |||
| Compound Name |
E,E-5-(4''-Methoxybiphenyl-4-yl)-penta-2,4-dienoic acid Nhydroxyamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL538364; BDBM50293369
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[23] | |||
| Compound Name |
2-[2-(2,3-Dihydro-1,4-benzodioxin-6-yl)-2-oxoethyl]sulfanyl-4-methyl-1H-pyrimidin-6-one
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL1800377; SCHEMBL17382809; BDBM50348378
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[20] | |||
| Compound Name |
2-[(4-Methyl-6-oxo-1,6-dihydropyrimidin-2-yl)sulfanyl]-N-(2-phenylethyl)acetamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
MLS000531589; CHEMBL1722433; SMR000136527; 2-[(4-methyl-6-oxo-1,6-dihydro-2-pyrimidinyl)thio]-N-(2-phenylethyl)acetamide; Oprea1_304490; cid_892234; BDBM96613; HMS2466G16; STK116346; ZINC18093765; AKOS000716785; AKOS001049225; MCULE-1856560484; SR-01000264561; SR-01000264561-1; Z56847664; 2-[(4-keto-6-methyl-1H-pyrimidin-2-yl)thio]-N-phenethyl-acetamide; 2-[(6-methyl-4-oxo-1H-pyrimidin-2-yl)sulfanyl]-N-(2-phenylethyl)acetamide; 2-[(6-methyl-4-oxo-1H-pyrimidin-2-yl)thio]-N-(2-phenylethyl)acetamide
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[20] | |||
| Compound Name |
N-Hydroxy-3-[1-(2-thiophen-3-ylethyl)triazol-4-yl]benzamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL2178343; NCC-142; BDBM50399673
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[6] | |||
| Compound Name |
N-Hydroxy-3-[2-(phenylsulfanylmethyl)-1,3-thiazol-4-yl]benzamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL4105617; NCC-170; BDBM50252383
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[33] | |||
| Compound Name |
2-[2-(4-Hydroxyphenyl)-2-oxoethyl]sulfanyl-4-methyl-1H-pyrimidin-6-one
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL1800376; BDBM50348377
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[20] | |||
| Compound Name |
N-{4-[2-(4,6-Dimethyl-pyrimidin-2-ylsulfanyl)-acetyl]-phenyl}-acetamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL1800244; Oprea1_373990; Oprea1_543124; ZINC841137; BDBM50348391; STK285981; AKOS001628005; MCULE-9514505423; N-(4-{[(4,6-dimethylpyrimidin-2-yl)sulfanyl]acetyl}phenyl)acetamide
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[20] | |||
| Compound Name |
N-[(2S)-1-[[6-(2-Amino-5-thiophen-2-ylanilino)-6-oxohexyl]amino]-3-(1H-indol-3-yl)-1-oxopropan-2-yl]-4-methoxybenzamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL4065117; BDBM50242038
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[30] | |||
| Compound Name |
6-Methyl-2-phenacylsulfanyl-1H-pyrimidin-4-one
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL1800250; 2-((4-hydroxy-6-methylpyrimidin-2-yl)thio)-1-phenylethanone; 6-methyl-2-(2-oxo-2-phenylethylthio)-3-hydropyrimidin-4-one; NSC338484; CBKinase1_000908; CBKinase1_013308; Cambridge id 5509606; IFLab1_000456; CTK0H7748; DTXSID70319010; HMS1413E16; ZINC9446020; BDBM50348397; SBB085164; STK830457; STL281533; 6-methyl-2-[(2-oxo-2-phenylethyl)sulfanyl]-3,4-dihydropyrimidin-4-one; AKOS000565987; AKOS001012387; AKOS003626716; MCULE-4095585670; NSC-338484; IDI1_008675; ST50113123; 2-Benzoylmethylmercapto-4-methyl-6-oxypyrimidin; AB00087040-01; SR-01000416787; SR-01000416787-1; BRD-K22643941-001-01-6; Z56767694; F0176-0059; 6-methyl-2-(2-oxo-2-phenylethyl-thio)pyrimidin-4(3h)-one; 6-methyl-2-[(2-oxo-2-phenylethyl)thio]-4(1H)-pyrimidinone; 2-[(4-hydroxy-6-methylpyrimidin-2-yl)sulfanyl]-1-phenylethanone; 6-METHYL-2-((2-OXO-2-PHENYLETHYL)THIO)-4(3H)-PYRIMIDINONE; 6-methyl-2-[(2-oxo-2-phenylethyl)sulfanyl]-4(3H)-pyrimidinone; 6-methyl-2-[(2-oxo-2-phenylethyl)sulfanyl]pyrimidin-4(3H)-one
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[20] | |||
| Compound Name |
N-Methyl-N-[4-[2-[(4-methyl-6-oxo-1H-pyrimidin-2-yl)sulfanyl]acetyl]phenyl]acetamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL1800251; BDBM50348372
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[20] | |||
| Compound Name |
(1R,14S,17R,23S)-23-Benzyl-4-oxa-7,8-dithia-15,21,24,26-tetrazatricyclo[12.11.2.017,21]heptacosane-16,22,25,27-tetrone
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL2158742; BDBM50394110
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[34] | |||
| Compound Name |
2-(Tert-butylcarbonylmethylthio)-4-hydroxy-6-methylpyrimidine
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL1800382; Maybridge1_007088; CTK6C4190; HMS561K04; BDBM50348383; SBB099296; ZINC13468269; AKOS008981059; CCG-244729; MCULE-6331991984; 1-(4-hydroxy-6-methylpyrimidin-2-ylthio)-3,3-dimethylbutan-2-one
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[20] | |||
| Compound Name |
2-(4-Chlorophenacylthio)-4-hydroxy-6-methylpyrimidine
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL1800375; 2-[2-(4-chlorophenyl)-2-oxoethylthio]-6-methyl-3-hydropyrimidin-4-one; BAS 00853818; MLS001143876; CTK6G9149; CCG-304; BDBM50348376; SBB085170; STL281529; STL330245; ZINC17750270; AKOS000565394; AKOS001021795; AKOS003625541; MCULE-8980888190; SMR000473315; ST50113505; AE-641/01210025; SR-01000637247-1; 1-(4-Chlorophenyl)-2-((4-hydroxy-6-methylpyrimidin-2-yl)thio)ethan-1-one; 1-(4-chlorophenyl)-2-[(4-hydroxy-6-methylpyrimidin-2-yl)thio]ethanone; 2-((2-(4-Chlorophenyl)-2-oxoethyl)thio)-6-methylpyrimidin-4(3H)-one; 2-{[2-(4-chlorophenyl)-2-oxoethyl]sulfanyl}-6-methyl-4(3H)-pyrimidinone; 2-{[2-(4-chlorophenyl)-2-oxoethyl]sulfanyl}-6-methylpyrimidin-4(1H)-one; 2-{[2-(4-chlorophenyl)-2-oxoethyl]sulfanyl}-6-methylpyrimidin-4(3H)-one
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[20] | |||
| Compound Name |
Nampt-IN-3
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL4065412; BDBM50241438; HY-108701; CS-0030130
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[35] | |||
| Compound Name |
Hdac3-IN-T326
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3622375; N-(2-Aminophenyl)-5-(1-(3-nitrophenethyl)-1H-1,2,3-triazol-4-yl)thiophene-2-carboxamide; BDBM50121211; T-326; N-(2-aminophenyl)-5-[1-[2-(3-nitrophenyl)ethyl]triazol-4-yl]thiophene-2-carboxamide
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[3] | |||
| Compound Name |
2-[(4-Hydroxy-6-methylpyrimidin-2-yl)sulfanyl]-1-(4-methoxyphenyl)ethanone
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL1307946; SMR000104980; CBMicro_000564; Oprea1_387281; Oprea1_513871; MLS000109033; REGID_for_CID_722456; HMS2167C19; HMS3314O04; SMSF0007972; ZINC8632101; BDBM50348374; STK927199; STL281551; AKOS000566015; AKOS002232718; AKOS008969277; CB01814; MCULE-2661039450; BIM-0000433.P001; ST50112774; AB00097791-01; AB00097791-06; SR-01000417195; SR-01000417195-1; 2-[2-(4-methoxyphenyl)-2-oxoethylthio]-6-methyl-3-hydropyrimidin-4-one; 2-{[2-(4-methoxyphenyl)-2-oxoethyl]sulfanyl}-6-methylpyrimidin-4(3H)-one
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[20] | |||
| Compound Name |
Chembl4165684
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
BDBM50283687
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[36] | |||
| Compound Name |
(7R)-N-Hydroxy-7-[(4-pyridin-3-ylpyrimidin-2-yl)amino]-5,6,7,8-tetrahydronaphthalene-2-carboxamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3338418; BDBM50027662
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[26] | |||
| Compound Name |
N-(2-Aminophenyl)-4-[1-[2-(3-thienyl)ethyl]-1H-1,2,3-triazol-4-yl]benzamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
HDAC3-IN-T247; CHEMBL3622374; SCHEMBL18208054; BDBM50121210; MFCD29089340; T 247; T-247; N-(2-aminophenyl)-4-[1-(2-thiophen-3-ylethyl)triazol-4-yl]benzamide
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[37] | |||
| Compound Name |
(2R)-2-[(1-Hydroxy-6-sulfanylidenepyridine-2-carbonyl)amino]propanoic acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3260857; BDBM50014160
Click to Show/Hide
|
||||
| Activity |
IC50 = 100000 nM
|
[25] | |||
| Compound Name |
Methyl 2-((4-hydroxy-6-methylpyrimidin-2-yl)thio)acetate
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL1800380; methyl 2-(6-methyl-4-oxo-3-hydropyrimidin-2-ylthio)acetate; BDBM50348381; SBB062603; STK641838; STL281936; ZINC13739146; AKOS002262380; AKOS002308199; AKOS008981057; MCULE-6551097558; 2-Methoxycarbonylmethylenethio-6-methyluracil; ST50186106; methyl [(4-hydroxy-6-methylpyrimidin-2-yl)sulfanyl]acetate; methyl [(4-methyl-6-oxo-1,6-dihydropyrimidin-2-yl)sulfanyl]acetate; [(4-Oxo-3,4-dihydro-6-methylpyrimidine-2-yl)thio]acetic acid methyl ester; METHYL ((4-METHYL-6-OXO-1,6-DIHYDRO-2-PYRIMIDINYL)THIO)ACETATE; Methyl [(4-methyl-6-oxo-1,6-dihydro-2-pyrimidinyl)sulfanyl]acetate #
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[20] | |||
| Compound Name |
1-(3,4-Dihydroxyphenyl)-2-[(4-hydroxy-6-methylpyrimidin-2-YL)thio]ethanone
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL209453; CHEMBRDG-BB 6606317; MLS001212148; SMR000518041; 1-(3,4-Dihydroxy-phenyl)-2-(4-hydroxy-6-methyl-pyrimidin-2-ylsulfanyl)-ethanone; 1-(3,4-Dihydroxyphenyl)-2-((4-hydroxy-6-methylpyrimidin-2-yl)thio)ethanone; Cambridge id 6606317; Oprea1_441814; cid_687937; SCHEMBL17382815; BDBM55151; CTK4I6835; DTXSID20350771; KUC104368N; BDBM50477568; MFCD02366437; STK770887; ZINC18163844; 2-[2-(3,4-dihydroxyphenyl)-2-oxoethyl]sulfanyl-6-methyl-1H-pyrimidin-4-one; AKOS000563316; AKOS001653377; AKOS008967906; KSC-10-146; MCULE-3270859217; W-9419; 2-[[2-(3,4-dihydroxyphenyl)-2-oxoethyl]thio]-6-methyl-1H-pyrimidin-4-one; 2-{[2-(3,4-dihydroxyphenyl)-2-oxoethyl]thio}-6-methylpyrimidin-4(3H)-one; 1-(3,4-dihydroxyphenyl)-2-(4-hydroxy-6-methyl-pyrimidin-2-yl)sulfanyl-ethanone; 1-(3,4-Dihydroxyphenyl)-2-[(4-hydroxy-6-methyl-2-pyrimidinyl)thio]ethanone; 2-[[2-(3,4-dihydroxyphenyl)-2-keto-ethyl]thio]-6-methyl-1H-pyrimidin-4-one; 2-{[2-(3,4-dihydroxyphenyl)-2-oxoethyl]sulfanyl}-6-methylpyrimidin-4(3H)-one; Ethanone, 1-(3,4-dihydroxyphenyl)-2-[(4-hydroxy-6-methyl-2-pyrimidinyl)thio]-
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[20] | |||
| Compound Name |
N-(2-Aminophenyl)-4-[[[(4R,5S)-4,5-diphenyl-1,3-oxazolidin-2-ylidene]amino]methyl]benzamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3605506; BDBM50113971
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[38] | |||
| Compound Name |
6-[2-[(4-Methyl-6-oxo-1H-pyrimidin-2-yl)sulfanyl]acetyl]-1,3-dihydroindol-2-one
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL1800378; SCHEMBL17382803; BDBM50348379
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[20] | |||
| Compound Name |
N-[4-[2-(4-Methoxy-6-methylpyrimidin-2-yl)sulfanylacetyl]phenyl]acetamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL1800243; BDBM50348390
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[20] | |||
| Compound Name |
Ethyl 4-[(4-methyl-6-oxo-1H-pyrimidin-2-yl)sulfanyl]-3-oxobutanoate
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL1800383; BDBM50348384; AKOS013207288
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[20] | |||
| Compound Name |
6-Methyl-2-{[2-oxo-2-(thiophen-2-yl)ethyl]sulfanyl}-3,4-dihydropyrimidin-4-one
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL1800379; ChemDiv3_001859; SCHEMBL13401534; HMS1478E11; BDBM50348380; ZINC18084678; AKOS001038722; AKOS008966863; CCG-107559; MCULE-5001803542; IDI1_020825; Z56864923
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[20] | |||
| Compound Name |
N-[4-[2-[(4-Methyl-6-oxo-1H-pyrimidin-2-yl)sulfanyl]acetyl]phenyl]benzamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL1800373; BDBM50348373
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[20] | |||
| Compound Name |
(1R,14S,17R,23S)-23-Methyl-4-oxa-7,8-dithia-15,21,24,26-tetrazatricyclo[12.11.2.017,21]heptacosane-16,22,25,27-tetrone
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3310509; BDBM50048861
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[24] | |||
| Compound Name |
(3S,6Z,9S,12R,16S)-6-Ethylidene-16-[(E)-4-methylsulfanylbut-1-enyl]-9-(methylsulfanylmethyl)-3,12-di(propan-2-yl)-1-oxa-4,7,10-triazacyclohexadecane-2,5,8,11,14-pentone
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL2093007
Click to Show/Hide
|
||||
| Activity |
IC50 = 110000 nM
|
[39] | |||
| Compound Name |
Chembl4167599
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
BDBM50285612
Click to Show/Hide
|
||||
| Activity |
IC50 = 117000 nM
|
[40] | |||
| Compound Name |
N-(2-Aminophenyl)-4-[(6-oxo-4-phenyl-1H-pyrimidin-2-yl)sulfanylmethyl]benzamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL259127; SCHEMBL7945906; BDBM50376851
Click to Show/Hide
|
||||
| Activity |
IC50 = 125000 nM
|
[41] | |||
| Compound Name |
(1S,5S,6R,9S,15E,20R)-20-Butyl-5-hydroxy-6-(2-methylpropyl)-2-oxa-11,12-dithia-7,19,22-triazabicyclo[7.7.6]docos-15-ene-3,8,18,21-tetrone
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3218564; BDBM50496769
Click to Show/Hide
|
||||
| Activity |
IC50 = 132500 nM
|
[22] | |||
| Compound Name |
N-(2-Aminophenyl)-7,7-di(1H-indol-3-yl)heptanamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL564916; ST-3071; SCHEMBL1308188; BDBM50297448
Click to Show/Hide
|
||||
| Activity |
IC50 = 150000 nM
|
[42] | |||
| Compound Name |
N-Hydroxy-2-propylpentanamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
Valproic acid hydroxamate; Valpropylhydroxamic Acid; CHEMBL186311; 2-Propylpentanehydroximic acid; SCHEMBL15310210; DTXSID50147530; Pentanamide, N-hydroxy-2-propyl-; VAHA, >=98% (HPLC); ZINC5298743; 2-Propyl-pentanoic acid hydroxyamide; BDBM50336884; AKOS017536923; BCB03_000831; J-001544; BRD-K96146874-001-01-2; Q27216290
Click to Show/Hide
|
||||
| Activity |
IC50 = 170000 nM
|
[7] | |||
| Compound Name |
N1-(2-Aminophenyl)-N7-phenylheptanediamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
NKL 22; N-(2-AMINOPHENYL)-N'-PHENYLHEPTANEDIAMIDE; Histone Deacetylase Inhibitor IV; HDAC inhibitor IV; CHEMBL277805; VC-4154 (HDAC inhibitor IV); N'-(2-AMINOPHENYL)-N-PHENYLHEPTANEDIAMIDE; Heptanediamide, N-(2-aminophenyl)-N'-phenyl-; NKL22; Probes2_000492; NKL-22; SCHEMBL1063954; CTK1E3681; DTXSID60429495; EX-A923; BCP16847; KS-00001CM1; BDBM50254774; MFCD16293760; s6548; ZINC29054251; AKOS027439961; CS-5542; N-Phenyl-N'-(2-aminophenyl)pimelamide; N1-2-Aminophenyl-N7-phenyl-heptanediamide; HY-100384; FT-0662016; N-(2-Aminophenyl)-N inverted exclamation mark -phenylheptanediamide
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 180000 nM
|
[3] | |||
| Click to Show/Hide the Information of All Poor Binders | |||||
| Non Binders of This Target (in total, 5 non binders) | Download | Top | |||
|---|---|---|---|---|---|
| Compound Name |
Valproate
Click to Show/Hide
|
Approved | Compound Info | ||
| Synonyms |
99-66-1; Dipropylacetic acid; Depakine; Depakene; 2-Propylvaleric acid; Ergenyl; Di-n-propylacetic acid; Mylproin; Pentanoic acid, 2-propyl-; 4-Heptanecarboxylic acid; Propylvaleric acid; n-Dipropylacetic acid; Myproic Acid; Di-n-propylessigsaure; n-DPA; Dipropylacetate; Convulex; Depakin; Vupral; Acido valproico; Acide valproique; Acidum valproicum; Stavzor; Avugane; Baceca; Kyselina 2-propylvalerova; 2-n-Propyl-n-valeric acid; Acetic acid, dipropyl-; Abbott 44090; Valproinsaeure; Savicol; Convulsofin; Deproic; VPA; Depakin chrono; Dipropyl Acetate; Med Valproic; Valproic acid USP; Valproic acid USP24; Acide valproique [INN-French]; Acido valproico [INN-Spanish]; Acidum valproicum [INN-Latin]; Alti-Valproic; Depakote (TM); Dom-Valproic; G2M-777; Kyselina 2-propylvalerova [Czech]; N-DPA; N-Dipropylacetic acid; Novo-Valproic; Nu-Valproic; PMS-Valproic Acid; Penta-Valproic; Valproic acid (USP); Di-n-propylessigsaeure; Di-n-propylessigsaure [German]; Valproic acid [USAN:INN:BAN]; Valproic Acid, SodiumSalt (2:1); 2 PP (base)
Click to Show/Hide
|
||||
| Activity |
IC50 > 2000000 nM
|
[7] | |||
| Compound Name |
Phenylbutyrate
Click to Show/Hide
|
Phase 2 | Compound Info | ||
| Synonyms |
Benzenebutyric acid; Phenyl butanoate; Phenyl butyrate; HDInhib_000004; Butanoic acid, phenyl ester; Butyric acid, phenyl ester; FR-2080; Gamma-Phenylbutyric acid; Omega-Phenylbutanoic acid; GAMMA-PHENYL-BUTYRIC ACID; Butyric acid, 4-phenyl-(8CI); 1-Phenylbutyric acid; 4-PHENYL-BUTANOIC ACID; 4-PHENYLBUTYRIC ACID; 4-Phenylbutanoic acid; 4-phenylbutans; 4-phenylbutyrate
Click to Show/Hide
|
||||
| Activity |
IC50 > 2000000 nM
|
[7] | |||
| Compound Name |
Butanoic Acid
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|
Investigative | Compound Info | ||
| Synonyms |
butyric acid; butanoic acid; n-Butyric acid; 107-92-6; n-Butanoic acid; propylformic acid; ethylacetic acid; 1-propanecarboxylic acid; Butanic acid; butyrate; 1-Butyric acid; Buttersaeure; butanoate; Kyselina maselna; Butyric acid (natural); Propanecarboxylic acid; Buttersaeure [German]; 1-butanoic acid; FEMA Number 2221; Kyselina maselna [Czech]; FEMA No. 2221; CCRIS 6552; HSDB 940; butoic acid; Ethyacetic Acid; 2-butanoate; NSC 8415; UNII-40UIR9Q29H; UN2820; AI3-15306; EINECS 203-532-3; BRN 0906770; CH3-[CH2]2-COOH; 40UIR9Q29H
Click to Show/Hide
|
||||
| Activity |
IC50 > 2000000 nM
|
[7] | |||
| Compound Name |
3-Hex-5-enyl-1-[12-(1-oct-7-enylpyridin-1-ium-3-yl)dodecyl]pyridin-1-ium;chloride;iodide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL226817
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|
||||
| Activity |
IC50 > 200000 nM
|
[43] | |||
| Compound Name |
N-Hydroxybutanamide
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|
Investigative | Compound Info | ||
| Synonyms |
Butyrylhydroxamic acid; CHEMBL1672332; N-hydroxybutyramide; butyrohydroxamic acid; (n-propyl)hydroxamic acid; SCHEMBL264922; DTXSID10329294; ZINC4809144; BDBM50336883; AKOS000170033; MCULE-8710375368; Butyrylhydroxamic acid, >=98% (HPLC); EN300-72141; Z59181937
Click to Show/Hide
|
||||
| Activity |
IC50 > 2000000 nM
|
[7] | |||
| References | Top | ||||
|---|---|---|---|---|---|
| REF 1 | Optimization of biaryl Selective HDAC1&2 Inhibitors (SHI-1:2). Bioorg Med Chem Lett. 2008 Jan 15;18(2):726-31. | ||||
| REF 2 | Thailandepsins: bacterial products with potent histone deacetylase inhibitory activities and broad-spectrum antiproliferative activities. J Nat Prod. 2011 Oct 28;74(10):2031-8. | ||||
| REF 3 | Class I HDAC Inhibitors: Potential New Epigenetic Therapeutics for Alcohol Use Disorder (AUD). J Med Chem. 2018 Mar 8;61(5):1745-1766. | ||||
| REF 4 | Exploration of the internal cavity of histone deacetylase (HDAC) with selective HDAC1/HDAC2 inhibitors (SHI-1:2). Bioorg Med Chem Lett. 2008 Feb 1;18(3):973-8. | ||||
| REF 5 | Bioorg Med Chem Lett. 2008 Dec 1;18(23):6104-9. Epub 2008 Oct 14.SAR profiles of spirocyclic nicotinamide derived selective HDAC1/HDAC2 inhibitors (SHI-1:2). | ||||
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