Target Poor or Non Binder(s) Information
| Target General Information | Top | ||||
|---|---|---|---|---|---|
| Target ID | T62815 | Target Info | |||
| Target Name | UDP-glucuronosyltransferase 2B7 (UGT2B7) | ||||
| Synonyms |
ugt3; Uridine diphosphate glucuronosyltransferase; UDPGT
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| Target Type | Literature-reported Target | ||||
| Gene Name | ugt3 | ||||
| Biochemical Class | Hexosyltransferase | ||||
| UniProt ID | |||||
| Poor Binders of This Target (in total, 11 binders) | Download | Top | |||
|---|---|---|---|---|---|
| Compound Name |
Zidovudine
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Approved | Compound Info | ||
| Synonyms |
zidovudine; Azidothymidine; 30516-87-1; 3'-Azido-3'-deoxythymidine; Retrovir; AZT; Zidovudinum; Compound S; Thymidine, 3'-azido-3'-deoxy-; ZIDOVUDINE [AZT]; zidovudin; BW A509U; Zidovudinum [Latin]; Zidovudina [Spanish]; BWA509U; DRG-0004; 3'-Azido-2',3'-Dideoxythymidine; ZDV; UNII-4B9XT59T7S; 3'-Deoxy-3'-azidothymidine; CCRIS 105; Aztec; BW-A509U; BW-A-509U; HSDB 6515; 3'-Azido-3'-deoxythymidine (AIDS); CHEMBL129; NSC 602670; BW-A 509U; MLS000028548; 4B9XT59T7S; AZT; Antiviral; Azidodeoxythymidine; ZVD; Zidovudin; Zidovudina; AZT Antiviral; AZT TRANSPLACENTAL CARCINOGENESIS STUDY; Antiviral AZT; Cpd S; Racemic Liposomal AZT; Zidovudine EP III; BWA 509U; K7 [P Ti2 W10 O40]; AZT & EPO; AZT & HPA; AZT & Lymphoblastoid Interferon; AZT & SST; AZT & rsT4; AZT & sCD4; AZT & srCD4; AZT (Antiviral); AZT+PRO 140; AZT, Antiviral; Apo-Zidovudine; BWA-509U; Intron A & AZT; Novo-Azt; Propolis+AZT; Retrovir (TN); Retrovir(TM); Retrovis (TN); Zidovudine+PRO 140; AZT & Colony-stimulating factor 2; AZT & Concanavalin A (ConA); AZT & GM-CSF; AZT & IFN-alpha; AZT & IL-1; AZT & IL-2; AZT & IL-6; AZT & Li & EPO; AZT & NP (from PHCA or HSA); AZT & PM-19; DS-4152 & AZT; Liposomal AZT-SN-1; Liposomal AZT-SN-3; PC-SOD+AZT;RIFN-beta seron & AZT; AZT & CD4(178)-PE 40; AZT & Li & GM-CSF; AZT & Li & IL-1; AZT & Li & IL-6; AZT & rIFNalpha2; Racemic-dipalmitoylglycerophospho-AZT (in a lipid vesicle); Zidovudine (JAN/USP/INN); Zidovudine [USAN:INN:BAN:JAN]; AZT & rsCD4 & rIFNalphaA; SN-1-dipalmitoylglycerophospho-AZT (in a lipid vesicle); SN-3-dipalmitoylglycerophospho-AZT (in a lipid vesicle); AZT & Interferon-alpha-2; Met-SDF-1beta & AZT; Met-SDF-1beta & Zidovudine; Interferon AD + 3'-azido-3'-deoxythymidine; 1-(3-Azido-2,3-dideoxy-beta-D-ribofuranosyl)thymine; 3′-Azido-3′-deoxythymidine; 3' Azido 2',3' Dideoxythymidine; 3' Azido 3' deoxythymidine; 3'-Azido-3'-deoxythymidine & Concanavalin A; 3'-Azido-3'-deoxythymidine & Erythropoietin; 3'-Azido-3'-deoxythymidine & Heteropolyoxotungstate PM-19; 3'-Azido-3'-deoxythymidine & Interleukin-1; 3'-Azido-3'-deoxythymidine & Interleukin-2; 3'-Azido-3'-deoxythymidine & Interleukin-6; 3'-Azido-3'-deoxythymidine & Lithium & Erythropoietin; 3'-Azido-3'-deoxythymidine & Lithium & Interleukin-1; 3'-Azido-3'-deoxythymidine & Lithium & Interleukin-6; 3'-Azido-3'-deoxythymidine & Lymphoblastoid Interferon; 3'-Azido-3'-deoxythymidine & Sho-Saiko-To; 3'-Azido-3'deoxythymidine & Interferon-alpha; 3'-Azidothymidine; 3'-azido-3'-deoxythymidine, AZT; 3-Azido-3-deoxythymidine; Dendrigen; CTCE-0422
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| Activity |
Ki = 150000 nM
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[1] | |||
| Compound Name |
(R)-(+)-1-(2-Naphthyl)ethanol
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Investigative | Compound Info | ||
| Synonyms |
(R)-(+)-alpha-Methyl-2-naphthalenemethanol; (R)-1-(Naphthalen-2-yl)ethanol; (R)-1-(2-naphthyl)ethanol; CHEMBL206560; MFCD00075344; (1R)-1-naphthalen-2-ylethanol; SCHEMBL445001; DTXSID50426276; ZINC1038916; ANW-31420; BDBM50183596; (+)-(R)-1-Naphthalen-2-ylethanol; AKOS012670050; AKOS015840846; (1R)-1-(naphthalen-2-yl)ethan-1-ol; KS-0000160R; (R)-(+)-2-(1-Hydroxyethyl)naphthalene; AS-60197; SC-49300; (R)-(+)-1-(2-Naphthyl)ethanol, 98%; FT-0772654; N0784; (R)-(+)-ALPHA-METHYL-2-NAPHTHALENE-METHA
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| Activity |
IC50 = 79000 nM
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[2] | |||
| Compound Name |
5,7-Dimethyltetralin-1-ol
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL206457; SCHEMBL6799194; BDBM50183611; AKOS012028945; (rac)-5,7-dimethyl-1,2,3,4-tetrahydronaphthalen-1-ol
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| Activity |
Ki = 101000 nM
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[2] | |||
| Compound Name |
(S)-(-)-1-(2-Naphthyl)ethanol
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Investigative | Compound Info | ||
| Synonyms |
(s)-1-(naphthalen-2-yl)ethanol; (S)-(-)-alpha-Methyl-2-naphthalenemethanol; (S)-1-(2-naphthyl)ethanol; CHEMBL206369; (1S)-1-naphthalen-2-ylethanol; (1S)-1-(Naphthalen-2-Yl)Ethan-1-Ol; SCHEMBL483413; 1-(S)-(naphthalen-2-yl)ethanol; ZINC1038915; (1S)-1-(2-naphthyl)ethan-1-ol; ANW-26229; BDBM50183606; MFCD00064188; AKOS015840851; (S)-alpha-methyl-2-naphthalenemethanol; VC30250; (+/-)-(S)-1-Naphthalen-2-ylethanol; (S)-(-)-2-(1-Hydroxyethyl)naphthalene; AS-60389; 2-Naphthalenemethanol, a-methyl-, (aS)-; N0785; ST51037639; (S)-(-)-alpha-Methyl-2-naphthalenemethanol, 98%; J-016810
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| Activity |
IC50 = 105000 nM
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[2] | |||
| Compound Name |
(Rac)-6-methyl-3,4-dihydro-2H-chromen-4-ol
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL204019; SCHEMBL8251432; BDBM50183598; AKOS014312910
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| Activity |
Ki = 113000 nM
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[2] | |||
| Compound Name |
(R)-1-(Naphthalen-1-yl)ethanol
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Investigative | Compound Info | ||
| Synonyms |
(R)-(+)-1-(1-Naphthyl)ethanol; (1R)-1-naphthalen-1-ylethanol; R-(-)-1-(1-Naphthalenyl)ethanol; (R)-1-(1-naphthyl)ethanol; CHEMBL378554; MFCD00077830; (1R)-1-(Naphthalen-1-yl)ethan-1-ol; (1R)-1-(1-naphthyl)ethanol; PubChem14216; r-1-(1-naphthyl)ethanol; SCHEMBL1154786; R(+)-1-(1-naphthyl)ethanol; CTK4I5814; DTXSID90426275; ZINC1038913; ANW-58610; BDBM50183607; (+)-(R)-1-Naphthalen-1-ylethanol; AKOS012670048; AC-9387; CS-W017591; AS-60104; 1-Naphthalenemethanol, a-methyl-, (aR)-; (R)-(+)-; A?Methyl-1-naphthalenemethanol; DB-028798; 177N253; (R)-(+)-alpha-Methyl-1-naphthalenemethanol, 99%
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| Activity |
IC50 = 130000 nM
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[2] | |||
| Compound Name |
1-Naphthalenol, 1,2,3,4-tetrahydro-5,7-dimethyl-, (1R)-
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL383503; (r)-5,7-dimethyl-1-tetralol; BDBM50183614; ZINC13683712; AKOS015092950; (+/-)-(R)-5,7-Dimethyl-1-tetralol
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| Activity |
IC50 = 158000 nM
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[2] | |||
| Compound Name |
Epiestriol
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Investigative | Compound Info | ||
| Synonyms |
16-Epiestriol; Epioestriol; Actriol; 16b-hydroxyestradiol; Epiestriolum; Epioestriolum; 16-Epiestratriol; 16-epi-Estriol; 16b,17b-Estriol; UNII-8XZ32LI44K; 16beta-Hydroxyestradiol; 8XZ32LI44K; Estra-1,3,5(10)-triene-3,16beta,17beta-triol; Estra-1,3.5(10)-triene-3,16beta,17beta-triol; Epiestriolo; 3,17.beta.-Estriol; Epiestriolo [DCIT]; Epiestriol [INN:BAN]; Epiestriolum [INN-Latin]; 16-Epistriol; Estriol Impurity F; EINECS 208-937-9; 16beta,17beta-Estriol; 16.beta.-Hydroxyestradiol; Estriol (3,17.beta.); SCHEMBL221084; 16.beta.,17.beta.-Estriol; CHEMBL1908074; 16 -hydroxy-17 -estradiol; 16beta-Hydroxy-17beta-estradiol; DTXSID10894790; NSC26646; ZINC4213126; BDBM50088511; LMST02010006; MFCD00067609; NSC-26646; AKOS015916265; 16ss-17ss-Estriol; 16ss-Hydroxyestradiol; X2087; Estra-1,3,5(10)-triene-3,16b,17-triol; Estra-1,3,5(10)-triene-3,16b,17b-triol; estra-1,3,5(10)-triene-3,16beta,17-triol; 1,3,5(10)-Estratriene-3,16beta,17beta-triol; estra-1(10),2,4-triene-3,16beta,17beta-triol; 3,16beta,17beta-Trihydroxy-1,3,5(10)-estratriene; Estra-1,5(10)-triene-3,16.beta.,17.beta.-triol; Q24897913; (16beta,17beta)-estra-1(10),2,4-triene-3,16,17-triol; Estra-1,3,5(10)-triene-3,16,17-triol, (16beta,17beta)-; Estra-1,3,5(10)-triene-3,16beta,17beta-triol (16-epi-Estriol); Estra-1,5(10)-triene-3,16,17-triol, (16.beta.,17.beta.)-
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| Activity |
Ki = 162000 nM
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[3] | |||
| Compound Name |
1-Naphthalenol, 1,2,3,4-tetrahydro-5,7-dimethyl-, (1S)-
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL205772; BDBM50183620; ZINC13683733; AKOS017546902; (+)-(S)-5,7-Dimethyl-1-tetralol; 5,7-Dimethyl-1,2,3,4-tetrahydronaphthalene-1beta-ol
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| Activity |
IC50 = 166000 nM
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[2] | |||
| Compound Name |
(1S)-4-Methylindan-1-ol
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL380519; SCHEMBL1508536; (+)-(S)-4-Methyl-1-indalol; BDBM50183612; ZINC13683740; (1S)-4-methyl-2,3-dihydro-1H-inden-1-ol
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| Activity |
IC50 = 179000 nM
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[2] | |||
| Compound Name |
(4S)-6-Methyl-3,4-dihydro-2H-1-benzopyran-4-ol
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL382042; 2H-1-Benzopyran-4-ol, 3,4-dihydro-6-methyl-, (4S)-; (S)-6-Methylchroman-4alpha-ol; CTK0E0671; DTXSID60490180; BDBM50183619; ZINC13683736; (+/-)-(S)-6-Methyl-4-chromanol; AKOS017547089
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| Activity |
IC50 = 182000 nM
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[2] | |||
| Click to Show/Hide the Information of All Poor Binders | |||||
| Non Binders of This Target (in total, 23 non binders) | Download | Top | |||
|---|---|---|---|---|---|
| Compound Name |
Haloperidol
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Approved | Compound Info | ||
| Synonyms |
Aldo; Aloperidin; Aloperidol; Aloperidolo; Aloperidon; Bioperidolo; Brotopon; Dozic; Dozix; Eukystol; Fortunan; Galoperidol; Haldol; Halidol; Halojust; Halol; Halopal; Haloperido; Haloperidolum; Halopidol; Halopoidol; Halosten; Keselan; Linton; Mixidol; Pekuces; Peluces; Peridol; Pernox; Serenace; Serenase; Serenelfi; Sernas; Sernel; Sigaperidol; Ulcolind; Uliolind; Vesalium; Aloperidolo [DCIT]; Aloperidolo [Italian]; Einalon S; Haldol La; Haldol Solutab; Lealgin compositum; Pms Haloperidol; H 1512; R 1625; Aloperidin (TN); Apo-Haloperidol; Bioperidolo (TN); Brotopon (TN); Dozic (TN); Duraperidol (TN); Einalon S (TN); Eukystol (TN); Haldol (TN); Haloperidolum [INN-Latin]; Halosten (TN); Keselan (TN); Linton (TN);Novo-Peridol; Peluces (TN); R-1625; Serenace (TN); Serenase (TN); Sigaperidol (TN); Haloperidol (JP15/USP); McN-JR-1625; Haloperidol (JP15/USP/INN); Haloperidol [USAN:INN:BAN:JAN]
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| Activity |
Ki = 590000 nM
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[4] | |||
| Compound Name |
Valproate
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Approved | Compound Info | ||
| Synonyms |
99-66-1; Dipropylacetic acid; Depakine; Depakene; 2-Propylvaleric acid; Ergenyl; Di-n-propylacetic acid; Mylproin; Pentanoic acid, 2-propyl-; 4-Heptanecarboxylic acid; Propylvaleric acid; n-Dipropylacetic acid; Myproic Acid; Di-n-propylessigsaure; n-DPA; Dipropylacetate; Convulex; Depakin; Vupral; Acido valproico; Acide valproique; Acidum valproicum; Stavzor; Avugane; Baceca; Kyselina 2-propylvalerova; 2-n-Propyl-n-valeric acid; Acetic acid, dipropyl-; Abbott 44090; Valproinsaeure; Savicol; Convulsofin; Deproic; VPA; Depakin chrono; Dipropyl Acetate; Med Valproic; Valproic acid USP; Valproic acid USP24; Acide valproique [INN-French]; Acido valproico [INN-Spanish]; Acidum valproicum [INN-Latin]; Alti-Valproic; Depakote (TM); Dom-Valproic; G2M-777; Kyselina 2-propylvalerova [Czech]; N-DPA; N-Dipropylacetic acid; Novo-Valproic; Nu-Valproic; PMS-Valproic Acid; Penta-Valproic; Valproic acid (USP); Di-n-propylessigsaeure; Di-n-propylessigsaure [German]; Valproic acid [USAN:INN:BAN]; Valproic Acid, SodiumSalt (2:1); 2 PP (base)
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| Activity |
Ki = 1600000 nM
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[5] | |||
| Compound Name |
(S)-(-)-1-(1-Naphthyl)ethanol
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Investigative | Compound Info | ||
| Synonyms |
(S)-1-Naphthalen-1-yl-ethanol; (S)-1-(Naphthalen-1-yl)ethanol; (S)-(-)-alpha-Methyl-1-naphthalenemethanol; (S)-(-)-1-(1-Naphtyl)ethanol; (1S)-1-naphthalen-1-ylethanol; MFCD00077831; (S)-1-(1-naphthyl)ethanol; CHEMBL208435; (S)-()-1-(1-Naphthyl)ethanol; (1S)-1-(naphthalen-1-yl)ethan-1-ol; (S)-(+)-alpha-Methyl-1-naphthalenemethanol; 1-(naphthalen-1-yl)ethan-1-ol; PubChem14217; SCHEMBL1155486; (1S)-1-(1-naphthyl)ethanol; S(-)-1-(1-naphthyl)ethanol; CTK4C9974; DTXSID50936062; ACT05133; s-(-)-1-(1-naphthalenyl)ethanol; ZINC1038912; (S)-(+)-1-(1-Naphthyl)ethanol; BDBM50183617; AKOS016842326; AC-6590; FS-2250; (+/-)-(S)-1-Naphthalen-1-ylethanol; (S)-(-)-1-(1-Hydroxyethyl)naphthalene; BR-47439; s-(-)-alpha-methyl-1-naphthalenemethanol; (S)-(-)- -Methyl-1-naphthalenemethanol; 1-Naphthalenemethanol, a-methyl-, (aS)-; AB0022562; (S)-(?)-alpha?Methyl-1-naphthalenemethanol; N1063; W3453; (s)-(-)-alpha-methyl-1-naphthalene-methanol; S-2167; 914N848; (S)-(-)-alpha-Methyl-1-naphthalenemethanol, 99%; J-009568; (S)-(-)-1-(1-Naphthyl)ethanol, puriss., >=99.0% (sum of enantiomers, GC)
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| Activity |
IC50 = 214000 nM
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[2] | |||
| Compound Name |
2H-1-Benzopyran-4-ol, 3,4-dihydro-6-methyl-, (4R)-
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL206757; CTK3B5341; DTXSID00467477; (+)-(R)-6-Methyl-4-chromanol; BDBM50183597; ZINC13683716; AKOS015062160; 6-Methyl-3,4-dihydro-2H-1-benzopyran-4beta-ol
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| Activity |
IC50 = 225000 nM
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[2] | |||
| Compound Name |
(R)-(-)-1-Indanol
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Investigative | Compound Info | ||
| Synonyms |
(R)-2,3-dihydro-1H-inden-1-ol; R(-)-1-Hydroxyindan; (1R)-2,3-dihydro-1H-inden-1-ol; R-(-)-1-Indanol; (R)-()-1-Indanol; CHEMBL383641; 1H-Inden-1-ol, 2,3-dihydro-, (1R)-; MFCD00064164; (1r)-indanol; (R)-1-Indanol; (R)-Indan-1-ol; SCHEMBL1355960; R-(-)-1-Indanol 98%; CTK2F2236; DTXSID80426269; ZINC901097; (R)-(-)-1-Indanol, 99%; BDBM50183613; AKOS015899565; CS-W013378; AS-11550; EN300-89304; M-3401; UNII-LHG5BD7LOR component YIAPLDFPUUJILH-SECBINFHSA-N
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| Activity |
IC50 = 275000 nM
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[2] | |||
| Compound Name |
(1R)-7-Methoxy-1,2,3,4-tetrahydronaphthalen-1-ol
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL206379; (r)-7-methoxy-1-tetralol; 7-Methoxytetralin-1alpha-ol; SCHEMBL6797543; CTK7A7715; BDBM50183618; ZINC13683704; (+/-)-(R)-7-Methoxy-1-tetralol; AKOS011389552; NE25791; EN300-89290
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| Activity |
IC50 = 284000 nM
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[2] | |||
| Compound Name |
(Z)-4-[5-[(3,5-Difluorophenyl)methyl]-1-[(2-fluorophenyl)methyl]-2-oxopyridin-3-yl]-4-hydroxy-1-[4-(4-pyrrol-1-ylphenyl)piperazin-1-yl]but-3-ene-1,2-dione
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL3398252; SCHEMBL15287472; BDBM50103451
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| Activity |
IC50 > 300000 nM
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[6] | |||
| Compound Name |
(S)-5-Methoxytetralin-1-ol
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL205701; (s)-5-methoxy-1-tetralol; (+)-(S)-5-Methoxy-1-tetralol; ZINC4829662; BDBM50183615; (1S)-5-METHOXY-1,2,3,4-TETRAHYDRONAPHTHALEN-1-OL
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| Activity |
IC50 = 301000 nM
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[2] | |||
| Compound Name |
6-Methyl-2,3-dihydro-1H-inden-1-ol
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Investigative | Compound Info | ||
| Synonyms |
6-methyl-1-indanol; 1H-Inden-1-ol, 2,3-dihydro-6-methyl-; CHEMBL202791; 6-methylindan-1-ol; 6-methylindane-1-ol; 2,3-DIHYDRO-6-METHYL-1H-INDEN-1-OL; SCHEMBL836185; CTK8C3965; KS-00001AVB; DTXSID60491551; 0306AB; ANW-70876; BDBM50183609; MFCD11219505; AKOS010642083; FS-6029; AM803467; (rac)-6-methyl-2,3-dihydro-1H-inden-1-ol
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| Activity |
Ki = 301000 nM
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[2] | |||
| Compound Name |
(r)-4-Methyl-indan-1-ol
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL202751; SCHEMBL1151022; BDBM50183601; ZINC13683719; (+/-)-(R)-4-Methyl-1-indalol; (1R)-4-methyl-2,3-dihydro-1H-inden-1-ol
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| Activity |
IC50 = 317000 nM
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[2] | |||
| Compound Name |
(R)-(-)-1,2,3,4-Tetrahydro-1-naphthol
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Investigative | Compound Info | ||
| Synonyms |
(R)-1,2,3,4-tetrahydronaphthalen-1-ol; (1R)-1,2,3,4-Tetrahydronaphthalen-1-ol; (R)-1-Tetralol; (R)-Tetralin-1-ol; (R)-(-)-alpha-Tetralol; CHEMBL203428; 1-Naphthalenol, 1,2,3,4-tetrahydro-, (1R)-; MFCD00063005; (R)-1,2,3,4-Tetrahydro-1-naphthol; MFCD00063006; (r)-tetralol; (-)-1,2,3,4-Tetrahydro-1-naphthol; (R)-?Tetralol; 24-Tetrahydro-1-naphthol; (R)-Tetrahydro-1-naphthol; SCHEMBL3596545; CTK8B1260; (R)-1,2,3,4-Tetrahydronaphthol; KS-000013SA; ZINC3860968; 1543AB; ANW-25104; BDBM50183616; AKOS013153128; AKOS015833097; AS-65542; (R)-1,2,3,4-Tetrahydro-1-naphthalenol; (R)-(+)-1,2,3,4-tetrahydro-1-naphthol; CS-0079970; (R)-1-Naphthol, (R)-1,2,3,4-tetrahydro-; (R)-(-)-1,2,3,4-Tetrahydro-1-naphthol, 99%; J-015080; UNII-87652943HP component JAAJQSRLGAYGKZ-SNVBAGLBSA-N
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| Activity |
IC50 = 337000 nM
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[2] | |||
| Compound Name |
(1R)-1-Anthracen-9-ylethanol
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL204218; (r)-1-(9-anthryl)ethanol; SCHEMBL7560523; ZINC2168355; (+)-(R)-1-Anthracen-9-ylethanol; BDBM50183599
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| Activity |
IC50 = 344000 nM
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[2] | |||
| Compound Name |
(1S)-7-Methoxy-1,2,3,4-tetrahydronaphthalen-1-ol
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL381981; (S)-7-Methoxytetralin-1-ol; SCHEMBL6805525; CTK7A7707; (+)-(S)-7-Methoxy-1-tetralol; BDBM50183608; ZINC13683726; AKOS017463694; NE25665; EN300-89291
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| Activity |
IC50 = 351000 nM
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[2] | |||
| Compound Name |
(+/-)-(R)-5-Methoxy-1-tetralol
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL381170; ZINC4829664; BDBM50183621
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| Activity |
IC50 = 366000 nM
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[2] | |||
| Compound Name |
(R)-6-Methylindan-1-ol
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL380136; SCHEMBL17571270; BDBM50183610; ZINC13683723; (+/-)-(R)-6-Methyl-1-indalol
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| Activity |
IC50 = 394000 nM
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[2] | |||
| Compound Name |
(S)-(+)-1,2,3,4-Tetrahydro-1-naphthol
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Investigative | Compound Info | ||
| Synonyms |
(S)-1,2,3,4-tetrahydronaphthalen-1-ol; (s)-1-tetralol; (1S)-1,2,3,4-tetrahydronaphthalen-1-ol; 1-Tetralol, (S)-; S-Tetralol; (S)-Tetralin-1-ol; (S)-(+)-alpha-Tetralol; CHEMBL206199; UNII-50MT77537D; 50MT77537D; (S)-1,2,3,4-tetrahydro-1-naphthol; (+)-1,2,3,4-Tetrahydro-1-naphthol; S)-(+)-1,2,3,4-Tetrahydro-1-naphthol; MFCD00063006; 1,2,3,4-Tetrahydro-naphthalen-1-ol; (s)-alpha-tetralol; (S)-1-Tetralinol; (+)-alpha-Tetralol; (+)-1-Tetralol; (S)-1-Hydroxytetralin; (S)-(+)-1-Tetralol; SCHEMBL3583014; SGCUT00116; BDBM26271; CTK8B1853; KS-000016UD; to_000012; ZINC3860967; ANW-31845; AKOS015833090; TS-01947; S-(+)-1,2,3,4-tetrahydro-1-naphthol; (1S)-1,2,3,4-tetrahydro-1-naphthalenol; J330.337C; CS-0079961; V1329; (S)-1-hydroxy-1,2,3,4-tetrahydronaphthalene; 1-Naphthalenol, 1,2,3,4-tetrahydro-, (1S)-; 732T471; A829313; (S)-(+)-1,2,3,4-Tetrahydro-1-naphthol, 99%; 1-Naphthalenol, 1,2,3,4-tetrahydro-, (S)-(+)-; Q27260807; UNII-87652943HP component JAAJQSRLGAYGKZ-JTQLQIEISA-N
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| Activity |
IC50 = 489000 nM
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[2] | |||
| Compound Name |
(4R)-3,4-Dihydro-2H-1-benzopyran-4-ol
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Investigative | Compound Info | ||
| Synonyms |
(R)-4-chromanol; (4R)-3,4-dihydro-2H-chromen-4-ol; CHEMBL206124; (r)-chroman-4-ol; (+)-(R)-4-Chromanol; 2H-1-Benzopyran-4-ol, 3,4-dihydro-, (4R)-; SCHEMBL819188; CTK7F2891; ZINC3860965; BDBM50183605; AKOS006237644; MCULE-9892478702; NE60336; EN300-69615; Z959151866
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| Activity |
IC50 = 507000 nM
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[2] | |||
| Compound Name |
(S)-(+)-1-Indanol
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Investigative | Compound Info | ||
| Synonyms |
(S)-2,3-dihydro-1H-inden-1-ol; (1S)-2,3-dihydro-1H-inden-1-ol; (S)-(+)-1-Hydroxyindan; (s)-indan-1-ol; CHEMBL381761; MFCD00064165; (S)-1-indanol; (1s)-indanol; (1S)-indan-1-ol; 1H-Inden-1-ol, 2,3-dihydro-, (1S)-; SCHEMBL3418678; CTK4F5936; ZINC901099; (S)-(+)-1-Indanol, 99%; BDBM50183600; CS-W013372; AS-59973; 1H-Inden-1-ol,2,3-dihydro-, (1S)-; V1332; EN300-89303; 501I320; J-016024; UNII-LHG5BD7LOR component YIAPLDFPUUJILH-VIFPVBQESA-N
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| Activity |
IC50 = 513000 nM
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[2] | |||
| Compound Name |
(4S)-3,4-Dihydro-2H-1-benzopyran-4-ol
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Investigative | Compound Info | ||
| Synonyms |
2H-1-Benzopyran-4-ol, 3,4-dihydro-, (4S)-; (4S)-3,4-dihydro-2H-chromen-4-ol; CHEMBL202957; (s)-4-chromanol; (s)-chroman-4-ol; (4S)chroman-4-ol; (R,S)-Chroman-4-ol; (+/-)-(S)-4-Chromanol; SCHEMBL2309021; CTK0C0646; ZINC3860966; BDBM50183604; SBB086707; AKOS017463708; NE35203; EN300-69614; Z959151868
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| Activity |
IC50 = 518000 nM
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[2] | |||
| Compound Name |
(S)-1-(Anthracene-9-yl)ethanol
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL204219; ZINC1593350; BDBM50183603; (+/-)-(S)-1-Anthracen-9-ylethanol
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| Activity |
IC50 = 532000 nM
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[2] | |||
| Compound Name |
(S)-6-Methylindan-1-ol
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL202955; SCHEMBL17571271; CTK0J0914; DTXSID60469896; (+)-(S)-6-Methyl-1-indalol; BDBM50183622; ZINC13683744; 1H-Inden-1-ol, 2,3-dihydro-6-methyl-, (1S)-
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| Activity |
IC50 = 540000 nM
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[2] | |||
| Compound Name |
(+/-)-(R)-7-Nitro-1-tetralol
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL381338; BDBM50183595; ZINC13683708; (1R)-7-NITRO-1,2,3,4-TETRAHYDRONAPHTHALEN-1-OL
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| Activity |
IC50 = 599000 nM
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[2] | |||
| Compound Name |
(+)-(S)-7-Nitro-1-tetralol
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL378390; BDBM50183602
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| Activity |
IC50 = 651000 nM
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[2] | |||
| Click to Show/Hide the Information of All Non Binders | |||||
| References | Top | ||||
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| REF 1 | Diabetes mellitus reduces activity of human UDP-glucuronosyltransferase 2B7 in liver and kidney leading to decreased formation of mycophenolic acid acyl-glucuronide metabolite. Drug Metab Dispos. 2011 Mar;39(3):448-55. | ||||
| REF 2 | Stereochemical sensitivity of the human UDP-glucuronosyltransferases 2B7 and 2B17. J Med Chem. 2006 Mar 9;49(5):1818-27. | ||||
| REF 3 | Regiospecificity and stereospecificity of human UDP-glucuronosyltransferases in the glucuronidation of estriol, 16-epiestriol, 17-epiestriol, and 13-epiestradiol. Drug Metab Dispos. 2013 Mar;41(3):582-91. | ||||
| REF 4 | Human UDP-glucuronosyltransferase isoforms involved in haloperidol glucuronidation and quantitative estimation of their contribution. Drug Metab Dispos. 2012 Feb;40(2):240-8. | ||||
| REF 5 | UDP-glucuronosyltransferases and clinical drug-drug interactions. Pharmacol Ther. 2005 Apr;106(1):97-132. | ||||
| REF 6 | A novel molecule with notable activity against multi-drug resistant tuberculosis. Bioorg Med Chem Lett. 2015 Mar 15;25(6):1269-73. | ||||
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